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Volume 7 (14); 2016

Research Paper

Selection, Analysis and Improvement of Anti-Angiogenesis Compounds Identified by an Anti-HIF-1α Screening and Validation System
Chikezie Madu, Liyuan Li, Yi Lu
J. Cancer 2016; 7(14): 1926-1938. doi:10.7150/jca.15603
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Impact of Systemic Therapy and Recurrence Pattern on Survival Outcome after Radiofrequency Ablation for Colorectal Liver Metastases
Axel Stang, Marcello Donati, Hauke Weilert, Karl Jürgen Oldhafer
J. Cancer 2016; 7(14): 1939-1949. doi:10.7150/jca.15656
[Abstract] [Full text] [PDF] [PubMed] [PMC]

In vivo Antitumor Effect of an HPV-specific Promoter driving IL-12 Expression in an HPV 16-positive Murine Model of Cervical Cancer
Victor Hugo Bermúdez-Morales, Geny Fierros-Zarate, Celina García-Meléndrez, Juan Manuel Alcocer-Gonzalez, Ausencio Morales-Ortega, Oscar Peralta-Zaragoza, Kirvis Torres-Poveda, Ana Isabel Burguete-García, Eva Hernández-Márquez, Vicente Madrid-Marina
J. Cancer 2016; 7(14): 1950-1959. doi:10.7150/jca.15536
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma
Giuseppe De Palma, Fabio Sallustio, Claudia Curci, Vanessa Galleggiante, Monica Rutigliano, Grazia Serino, Pasquale Ditonno, Michele Battaglia, Francesco P. Schena
J. Cancer 2016; 7(14): 1960-1967. doi:10.7150/jca.16123
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Early Integration of Palliative Care in Oncology Practice: Results of the Italian Association of Medical Oncology (AIOM) Survey
Vittorina Zagonel, Riccardo Torta, Vittorio Franciosi, Antonella Brunello, Guido Biasco, Daniela Cattaneo, Luigi Cavanna, Domenico Corsi, Gabriella Farina, Luisa Fioretto, Teresa Gamucci, Gaetano Lanzetta, Roberto Magarotto, Marco Maltoni, Cataldo Mastromauro, Barbara Melotti, Fausto Meriggi, Ida Pavese, Erico Piva, Cosimo Sacco, Giuseppe Tonini, Leonardo Trentin, Paola Ermacora, Antonella Varetto, Federica Merlin, Stefania Gori, Carmine Pinto, Stefano Cascinu, AIOM Simultaneous & Continuous Care (SCC) Task Force-ESMO-DCs
J. Cancer 2016; 7(14): 1968-1978. doi:10.7150/jca.14634
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The C-reactive Protein/Albumin Ratio Is an independent Prognostic Factor for Overall Survival in Patients with Nasopharyngeal Carcinoma Receiving Intensity-Modulated Radiotherapy
Chang-Juan Tao, Yuan-Yuan Chen, Feng Jiang, Xing-Lai Feng, Qi-Feng Jin, Ting Jin, Yong-Feng Piao, Xiao-Zhong Chen
J. Cancer 2016; 7(14): 2005-2011. doi:10.7150/jca.16210
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Investigating a Correlation between Chemoradiotherapy Schedule Parameters and Overall Survival in a real-life LD SCLC Patient Cohort
Farkhad Manapov, Chukwuka Eze, Maximilian Niyazi, Olarn Roengvoraphoj, Minglun Li, Nina-Sophie Hegemann, Guido Hildebrandt, Rainer Fietkau, Claus Belka
J. Cancer 2016; 7(14): 2012-2017. doi:10.7150/jca.16741
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Pregnancy Specific β-1 Glycoprotein 1 is Expressed in Pancreatic Ductal Adenocarcinoma and its Subcellular Localization Correlates with Overall Survival
Jasmin H. Shahinian, Hannah Fuellgraf, Stefan Tholen, Justin Mastroianni, Julia Daniela Knopf, Markus Kuehs, Bettina Mayer, Manuel Schlimpert, Birte Kulemann, Simon Kuesters, Jens Hoeppner, Ulrich F. Wellner, Martin Werner, Ulrich T. Hopt, Robert Zeiser, Peter Bronsert, Oliver Schilling
J. Cancer 2016; 7(14): 2018-2027. doi:10.7150/jca.15864
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Vitamin D3 Intake Dose and Common Cancer: A Population-Based Case Control Study in a Chinese Population
Henry WC Leung, Chih-Hsin Muo, Chung-Feng Liu, Agnes LF Chan
J. Cancer 2016; 7(14): 2028-2034. doi:10.7150/jca.16505
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways
Sami Benzina, Jason Harquail, Roxann Guerrette, Pierre O'Brien, Stéphanie Jean, Nicolas Crapoulet, Gilles A. Robichaud
J. Cancer 2016; 7(14): 2035-2044. doi:10.7150/jca.15200
[Abstract] [Full text] [PDF] [PubMed] [PMC]

AIB1 Genomic Amplification Predicts Poor Clinical Outcomes in Female Glioma Patients
Lihong Chen, Changwei Wang, Xinyuan Zhang, Ke Gao, Rui Liu, Bingyin Shi, Peng Hou
J. Cancer 2016; 7(14): 2052-2060. doi:10.7150/jca.16069
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Impact of Diabetes on the Risk of Prostate Cancer Development according to Body Mass Index: A 10-year Nationwide Cohort Study
Jin Bong Choi, Hyong Woo Moon, Young Hyun Park, Woong Jin Bae, Hyuk Jin Cho, Sung-Hoo Hong, Ji Youl Lee, Sae Woong Kim, Kyung-Do Han, U-Syn Ha
J. Cancer 2016; 7(14): 2061-2066. doi:10.7150/jca.16110
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Hedgehog Signaling Non-Canonical Activated by Pro-Inflammatory Cytokines in Pancreatic Ductal Adenocarcinoma
Yuqiong Wang, Gang Jin, Quanjiang Li, Zhiping Wang, Weimin Hu, Ping Li, Shude Li, Hongyu Wu, Xiangyu Kong, Jun Gao, Zhaoshen Li
J. Cancer 2016; 7(14): 2067-2076. doi:10.7150/jca.15786
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognostic impact of hormone receptor- and HER2-defined subtypes in inflammatory breast cancer treated with high-dose chemotherapy: a retrospective study
Laurys Boudin, Anthony Gonçalves, Patrick Sfumato, Renaud Sabatier, François Bertucci, Carole Tarpin, Magali Provansal, Gilles Houvenaeghel, Eric Lambaudie, Agnes Tallet, Michel Resbeut, Emmanuelle Charafe-Jauffret, Boris Calmels, Claude Lemarie, Jean-Marie Boher, Jean-Marc Extra, Patrice Viens, Christian Chabannon
J. Cancer 2016; 7(14): 2077-2084. doi:10.7150/jca.15797
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The role of copper transporter ATP7A in platinum-resistance of esophageal squamous cell cancer (ESCC)
Zhuang-hua Li, Rongjie Zheng, Jing-tang Chen, Jun Jia, Miaozhen Qiu
J. Cancer 2016; 7(14): 2085-2092. doi:10.7150/jca.16117
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Anti-cancer and Sensibilisation Effect of Triptolide on Human Epithelial Ovarian Cancer
Hui Hu, Liping Luo, Fei Liu, Danghua Zou, Sihong Zhu, Buzhen Tan, Tingtao Chen
J. Cancer 2016; 7(14): 2093-2099. doi:10.7150/jca.16178
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Rac1 overexpression is correlated with epithelial mesenchymal transition and predicts poor prognosis in non-small cell lung cancer
Yujuan Zhou, Qianjin Liao, Yaqian Han, Jie Chen, Zhigang Liu, Hang Ling, Jing Zhang, Wenjuan Yang, Linda Oyang, Longzheng Xia, Li Wang, Heran Wang, Lei Xue, Hui Wang, Bingqiang Hu
J. Cancer 2016; 7(14): 2100-2109. doi:10.7150/jca.16198
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Incidence and predictors of Bone Metastases (BM) and Skeletal-Related Events (SREs) in Small Cell Lung Cancer (SCLC): A Swiss patient cohort
Katrin Conen, Raphael Hagmann, Viviane Hess, Alfred Zippelius, Sacha I. Rothschild
J. Cancer 2016; 7(14): 2110-2116. doi:10.7150/jca.16211
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Lymphangiogenesis in Classical Hodgkin Lymphoma - Preliminary Study with Clinicopathological Correlations
Daniel Benharroch, Isebrand Prinsloo, Jacob Gopas, Irena Lazarev
J. Cancer 2016; 7(14): 2117-2123. doi:10.7150/jca.16389
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Co-expression of Achaete-Scute Homologue-1 and Calcitonin Gene-Related Peptide during NNK-Induced Pulmonary Neuroendocrine Hyperplasia and Carcinogenesis in Hamsters
Xu Naizhen, R. Ilona Linnoila, Shioko Kimura
J. Cancer 2016; 7(14): 2124-2131. doi:10.7150/jca.16399
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Chemomodulatory Potential of Bartogenic Acid Against DMBA/Croton Oil Induced Two-Step Skin Carcinogenesis in Mice
Chandragouda R. Patil, Bhavin M. Sonara, Umesh B. Mahajan, Kalpesh R. Patil, Dipak D. Patil, Ramchandra B. Jadhav, Sameer N. Goyal, Shreesh Ojha
J. Cancer 2016; 7(14): 2139-2147. doi:10.7150/jca.16446
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Novel Prognostic Score, Based on Preoperative Nutritional Status, Predicts Outcomes of Patients after Curative Resection for Gastric Cancer
Xuechao Liu, Haibo Qiu, Jianjun Liu, Shangxiang Chen, Dazhi Xu, Wei Li, Youqing Zhan, Yuanfang Li, Yingbo Chen, Zhiwei Zhou, Xiaowei Sun
J. Cancer 2016; 7(14): 2148-2156. doi:10.7150/jca.16455
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Impact of Clinical Stage on Radiation Doses to Organs at Risk Following Intensity-modulated Radiotherapy in Nasopharyngeal Carcinoma: A Prospective Analysis
Lin Xu, Ji-Jin Yao, Guan-Qun Zhou, Wang-Jian Zhang, Guo-Long Liu, Li-Zhi Liu, Jun Ma, Ying Sun
J. Cancer 2016; 7(14): 2157-2164. doi:10.7150/jca.16476
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Involvement of BAFF and APRIL in Resistance to Apoptosis of Acute Myeloid Leukemia
Lukasz Bolkun, Kamil Grubczak, Gabriela Schneider, Paula Zembko, Urszula Radzikowska, Paulina Singh, Janusz Kloczko, Mariusz Z. Ratajczak, Marcin Moniuszko, Andrzej Eljaszewicz
J. Cancer 2016; 7(14): 1979-1983. doi:10.7150/jca.15966
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Transcriptional cofactor Mask2 is required for YAP-induced cell growth and migration in bladder cancer cell
Liang Dong, Fan Lin, Wanjun Wu, Weiren Huang, Zhiming Cai
J. Cancer 2016; 7(14): 2132-2138. doi:10.7150/jca.16438
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Role of Urinary Biomarkers in the Diagnosis of Adenoma and Colorectal Cancer: A Systematic Review and Meta-Analysis
Emma Altobelli, Paolo Matteo Angeletti, Giovanni Latella
J. Cancer 2016; 7(14): 1984-2004. doi:10.7150/jca.16244
[Abstract] [Full text] [PDF] [PubMed] [PMC]

An Overview of Genetic Changes and Risk of Pancreatic Ductal Adenocarcinoma
Agnieszka K. Sarnecka, Malgorzata Zagozda, Marek Durlik
J. Cancer 2016; 7(14): 2045-2051. doi:10.7150/jca.15323
[Abstract] [Full text] [PDF] [PubMed] [PMC]