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Volume 8 (12); 2017

Research Paper

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients
Christophe Deben, Ken Op de Beeck, Jolien Van den Bossche, Julie Jacobs, Filip Lardon, An Wouters, Marc Peeters, Guy Van Camp, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels
J. Cancer 2017; 8(12): 2154-2162. doi:10.7150/jca.19254
[Abstract] [Full text] [PDF]

CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer
Wei Wu, Fan Wu, Zaozao Wang, Jiabo Di, Jie Yang, Pin Gao, Beihai Jiang, Xiangqian Su
J. Cancer 2017; 8(12): 2163-2172. doi:10.7150/jca.19940
[Abstract] [Full text] [PDF]

Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration
Ju Liu, Josephine Hoh
J. Cancer 2017; 8(12): 2184-2190. doi:10.7150/jca.19452
[Abstract] [Full text] [PDF]

Simultaneous Quantification of Serum Multi-Phospholipids as Potential Biomarkers for Differentiating Different Pathophysiological states of lung, stomach, intestine, and pancreas
Yumei Guo, Junling Ren, Xiaoou Li, Xiaofeng Liu, Ning Liu, Yanmin Wang, Zhili Li
J. Cancer 2017; 8(12): 2191-2204. doi:10.7150/jca.19128
[Abstract] [Full text] [PDF]

The Neutrophil-Lymphocyte Ratio Predicts Recurrence of Cervical Intraepithelial Neoplasia
Sungwook Chun, Kyusik Shin, Ki Hyung Kim, Heung Yeol Kim, Wankyu Eo, Ji Young Lee, Jeong Namkung, Sang Hoon Kwon, Suk Bong Koh, Hong-Bae Kim
J. Cancer 2017; 8(12): 2205-2211. doi:10.7150/jca.19173
[Abstract] [Full text] [PDF]

Reelin promotes adhesion of multiple myeloma cells to bone marrow stromal cells via integrin β1 signaling
Liang Lin, Xinwei Zhang, Li Cao, Quanming An, Jie Hao, Yan Zhang, Rong Jin, Yingjun Chang, Xiaojun Huang, Jin Lu, Qing Ge
J. Cancer 2017; 8(12): 2212-2222. doi:10.7150/jca.18808
[Abstract] [Full text] [PDF]

Circulating tumor cells and microemboli can differentiate malignant and benign pulmonary lesions
Mario Mascalchi, Cristina Maddau, Lapo Sali, Elena Bertelli, Francesca Salvianti, Stefania Zuccherelli, Marzia Matucci, Alessandra Borgheresi, Claudio Raspanti, Monica Lanzetta, Massimo Falchini, Ernesto Mazza, Alessandra Vella, Michaela Luconi, Pamela Pinzani, Mario Pazzagli
J. Cancer 2017; 8(12): 2223-2230. doi:10.7150/jca.18418
[Abstract] [Full text] [PDF]

Selective Gastric Cancer Patients with Peritoneal Seeding Benefit from Gastrectomy after Palliative Chemotherapy: A Propensity Score Matching Analysis
Shu-Qiang Yuan, Run-Cong Nie, Shi Chen, Xiao-Jiang Chen, Yong-Ming Chen, Li-Pu Xu, Li-Fang Yang, Zhi-Wei Zhou, Jun-Sheng Peng, Ying-Bo Chen
J. Cancer 2017; 8(12): 2231-2237. doi:10.7150/jca.18932
[Abstract] [Full text] [PDF]

Develop and validation a nomogram to predict the recurrent probability in patients with major salivary gland cancer
Chang-Hsien Lu, Chien-Ting Liu, Pei-Hung Chang, Chia-Yen Hung, Shau-Hsuan Li, Ta-Sen Yeh, Yung-Shin Hung, Wen-Chi Chou
J. Cancer 2017; 8(12): 2247-2255. doi:10.7150/jca.19461
[Abstract] [Full text] [PDF]

Development of a new analog of SGK1 inhibitor and its evaluation as a therapeutic molecule of colorectal cancer
Xuchun Liang, Chunling Lan, Jinzhe Zhou, Wencheng Fu, Xuesha Long, Yu An, Guanming Jiao, Kejin Wang, Yongqin Li, Jiahong Xu, Qi Huang, Bin Xu, Junjie Xiao
J. Cancer 2017; 8(12): 2256-2262. doi:10.7150/jca.19566
[Abstract] [Full text] [PDF]

MAP2K1 Mutation in Colorectal Cancer Patients: Therapeutic Challenge Using Patient-Derived Tumor Cell Lines
J. E. Kim, K.K. Kim, S. Y. Kim, J. Lee, S. H. Park, J. O. Park, Y. S. Park, H. Y. Lim, W. K. Kang, S. T. Kim
J. Cancer 2017; 8(12): 2263-2268. doi:10.7150/jca.19582
[Abstract] [Full text] [PDF]

Importance of maintaining body weight for prevention of distant metastasis of nasopharyngeal carcinoma: An alternative workflow for cancer-risk assessment
Wenna Zhang, Yupei Chen, Lei Chen, Xu Liu, Ying Sun, Yanming Li, Jun Ma
J. Cancer 2017; 8(12): 2269-2276. doi:10.7150/jca.19611
[Abstract] [Full text] [PDF]

Tat-interactive Protein-60KDA (TIP60) Regulates the Tumorigenesis of Lung Cancer In Vitro
Yang Yang, Jian Sun, Ting Chen, Zengyue Tao, Xianwei Zhang, Feng Tian, Xiao Zhou, Daru Lu
J. Cancer 2017; 8(12): 2277-2281. doi:10.7150/jca.19677
[Abstract] [Full text] [PDF]

Silencing of HJURP induces dysregulation of cell cycle and ROS metabolism in bladder cancer cells via PPARγ-SIRT1 feedback loop
Rui Cao, Gang Wang, Kaiyu Qian, Liang Chen, Guofeng Qian, Conghua Xie, Han C. Dan, Wei Jiang, Min Wu, Chin-Lee Wu, Yu Xiao, Xinghuan Wang
J. Cancer 2017; 8(12): 2282-2295. doi:10.7150/jca.19967
[Abstract] [Full text] [PDF]

Alcohol Consumption and Lung Cancer According to Ile349Val Polymorphism in ADH3 Gene: Beyond the Tobacco Smoking Effect
Ana Fernández-Somoano, Sara M Álvarez-Avellón, Ana Souto-García, Jesús Vioque, Eva M Navarrete-Muñoz, Adonina Tardón
J. Cancer 2017; 8(12): 2296-2302. doi:10.7150/jca.18853
[Abstract] [Full text] [PDF]

Identification of Transcription Factor YY1 as a Regulator of a Prostate Cancer-Specific Pathway Using Proteomic Analysis
Arum Park, Jiyeong Lee, Sora Mun, Doo Jin Kim, Byung Heun Cha, Kyong Tae Moon, Tag Keun Yoo, Hee-Gyoo Kang
J. Cancer 2017; 8(12): 2303-2311. doi:10.7150/jca.19036
[Abstract] [Full text] [PDF]

Pattern of distant extrahepatic metastases in primary liver cancer: a SEER based study
Wenrui Wu, Xingkang He, Dewi Andayani, Liya Yang, Jianzhong Ye, Yating Li, Yanfei Chen, Lanjuan Li
J. Cancer 2017; 8(12): 2312-2318. doi:10.7150/jca.19056
[Abstract] [Full text] [PDF]

Impact of Detection Method and Accompanying Ductal Carcinoma in Situ on Prognosis of T1a,bN0 Breast Cancer
Shih-Che Shen, Shir-Hwa Ueng, Chan-Keng Yang, Chi-Chang Yu, Yung-Feng Lo, Hsien-Kun Chang, Yung-Chang Lin, Shin-Cheh Chen
J. Cancer 2017; 8(12): 2328-2335. doi:10.7150/jca.19293
[Abstract] [Full text] [PDF]

Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance
Leiming Pi, Gangcai Zhu, Li She, Ming Wei, Guancheng Liu, Changhan Chen, Di Hu, Fusen Peng, Haolei Tan, Yong Liu, Donghai Huang, Yongquan Tian, Xin Zhang
J. Cancer 2017; 8(12): 2336-2345. doi:10.7150/jca.19411
[Abstract] [Full text] [PDF]

Development and Validation of a Serum Biomarker Panel for the Detection of Esophageal Squamous Cell Carcinoma through RNA Transcriptome Sequencing
Shan Xing, Xin Zheng, Li-Qiang Wei, Shi-Jian Song, Dan Liu, Ning Xue, Xiao-Min Liu, Mian-Tao Wu, Qian Zhong, Chu-Mei Huang, Mu-Sheng Zeng, Wan-Li Liu
J. Cancer 2017; 8(12): 2346-2355. doi:10.7150/jca.19465
[Abstract] [Full text] [PDF]

MicroRNA-204-5p inhibits invasion and metastasis of laryngeal squamous cell carcinoma by suppressing forkhead box C1
Wei Gao, Yongyan Wu, Xiaoling He, Chunming Zhang, Meixia Zhu, Bo Chen, Qingqing Liu, Xukuan Qu, Weiyan Li, Shuxin Wen, Binquan Wang
J. Cancer 2017; 8(12): 2356-2368. doi:10.7150/jca.19470
[Abstract] [Full text] [PDF]

Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma
Hailong Ma, Shufang Jin, Wenyi Yang, Zhuowei Tian, Shuli Liu, Yang Wang, Ge Zhou, Mei Zhao, Shalva Gvetadze, Zhiyuan Zhang, Jingzhou Hu
J. Cancer 2017; 8(12): 2384-2393. doi:10.7150/jca.19486
[Abstract] [Full text] [PDF]

Predictive Value of Primary Tumor Site for Loco-regional Recurrence in Early Breast Cancer Patients with One to Three Positive Axillary Lymphadenophy
Shaoqing Niu, Ge Wen, Yufeng Ren, Yiyang Li, Lingling Feng, Chengtao Wang, Xiaobo Huang, Bixiu Wen, Yujing Zhang
J. Cancer 2017; 8(12): 2394-2400. doi:10.7150/jca.19722
[Abstract] [Full text] [PDF]

Association of HLA-DRB1, HLA-DQB1 Polymorphisms with HPV 16 E6 Variants among Young Cervical Cancer Patients in China
Yan Hu, Jin-Ze Wu, Hua Zhu, Sheng-Hui Zhang, Yan-Ying Zhu, Yi-Yao Wu, Ci-Xia Shuai
J. Cancer 2017; 8(12): 2401-2409. doi:10.7150/jca.19809
[Abstract] [Full text] [PDF]

DNA-dependent protein kinase catalytic subunit functions in metastasis and influences survival in advanced-stage laryngeal squamous cell carcinoma
Sha-sha He, Yong Chen, Xiao-ming Shen, Hong-zhi Wang, Peng Sun, Jun Dong, Gui-fang Guo, Ju-gao Chen, Liang-ping Xia, Pei-li Hu, Hui-juan Qiu, Shou-sheng Liu, Yi-xin Zhou, Wei Wang, Wei-han Hu, Xiu-yu Cai
J. Cancer 2017; 8(12): 2410-2416. doi:10.7150/jca.20069
[Abstract] [Full text] [PDF]

Review

Osteopontin -- a promising biomarker for cancer therapy
Ran Wei, Janet Pik Ching Wong, Hang Fai Kwok
J. Cancer 2017; 8(12): 2173-2183. doi:10.7150/jca.20480
[Abstract] [Full text] [PDF]

Central Role of CEMIP in Tumorigenesis and Its Potential as Therapeutic Target
Li Li, Lin-Hai Yan, Shwetha Manoj, Ying Li, Lu Lu
J. Cancer 2017; 8(12): 2238-2246. doi:10.7150/jca.19295
[Abstract] [Full text] [PDF]

Epithelial-mesenchymal transition: potential regulator of ABC transporters in tumor progression
Zong-Sheng Jiang, Yan-Zi Sun, Shao-Ming Wang, Jun-Shan Ruan
J. Cancer 2017; 8(12): 2319-2327. doi:10.7150/jca.19079
[Abstract] [Full text] [PDF]

VSV based virotherapy in ovarian cancer: the past, the present and …future?
Beata Urszula Orzechowska, Marcin Jędryka, Katarzyna Zwolińska, Rafał Matkowski
J. Cancer 2017; 8(12): 2369-2383. doi:10.7150/jca.19473
[Abstract] [Full text] [PDF]