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Volume 8 (5); 2017

Research Paper

Monitoring of Blood Vessel Density Using Contrast-Enhanced High Frequency Ultrasound May Facilitate Early Diagnosis of Lymph Node Metastasis
Takuma Sato, Tomoaki Takemura, Tomoki Ouchi, Shiro Mori, Maya Sakamoto, Yoichi Arai, Tetsuya Kodama
J. Cancer 2017; 8(5): 704-715. doi:10.7150/jca.18027
[Abstract] [Full text] [PDF] [PubMed] [PMC]

An investigation of the role of gene copy number variations in sorafenib sensitivity in metastatic hepatocellular carcinoma patients
Ji Yun Lee, Mineui Hong, Jeeyun Lee, Sujin Lee, Kyoung-Mee Kim, Cheolkeun Park, Ho Yeong Lim
J. Cancer 2017; 8(5): 730-736. doi:10.7150/jca.17887
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Peripheral blood lymphocyte-to-monocyte ratio as a prognostic factor in advanced epithelial ovarian cancer: a multicenter retrospective study
Jia-yu Zhu, Cheng-cheng Liu, Liang Wang, Mei Zhong, Hai-lin Tang, Hua Wang
J. Cancer 2017; 8(5): 737-743. doi:10.7150/jca.17668
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Nomogram based on Inflammatory Factors C-Reactive Protein and Fibrinogen to Predict the Prognostic Value in Patients with Resected Non-Small Cell Lung Cancer
Qiuyao Zeng, Ning Xue, Danian Dai, Shan Xing, Xia He, Shibing Li, Yi Du, Chumei Huang, Linfang Li, Wanli Liu
J. Cancer 2017; 8(5): 744-753. doi:10.7150/jca.17423
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Evaluation of the safety and efficacy of radiofrequency ablation for treating benign thyroid nodules
Xiaoyin Tang, Dan Cui, Jiachang Chi, Zhi Wang, Tao Wang, Bo Zhai, Ping Li
J. Cancer 2017; 8(5): 754-760. doi:10.7150/jca.17655
[Abstract] [Full text] [PDF] [PubMed] [PMC]

In Vivo Imaging of Experimental Melanoma Tumors using the Novel Radiotracer 68Ga-NODAGA-Procainamide (PCA)
István Kertész, András Vida, Gábor Nagy, Miklós Emri, Antal Farkas, Adrienn Kis, János Angyal, Noémi Dénes, Judit P. Szabó, Tünde Kovács, Péter Bai, György Trencsényi
J. Cancer 2017; 8(5): 774-785. doi:10.7150/jca.17550
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Hedgehog signaling pathway regulates ovarian cancer invasion and migration via adhesion molecule CD24
Chunyan Zeng, Tingtao Chen, Yan Zhang, Qi Chen
J. Cancer 2017; 8(5): 786-792. doi:10.7150/jca.17712
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Overexpression of MYC and BCL2 Predicts Poor Prognosis in Patients with Extranodal NK/T-cell Lymphoma, Nasal Type
Jing-hua Wang, Xi-wen Bi, Peng-fei Li, Zhong-jun Xia, Hui-qiang Huang, Wen-qi Jiang, Yu-jing Zhang, Liang Wang
J. Cancer 2017; 8(5): 793-800. doi:10.7150/jca.17766
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Protein Regulator of Cytokinesis PRC1 Confers Chemoresistance and Predicts an Unfavorable Postoperative Survival of Hepatocellular Carcinoma Patients
Yu Wang, Feng Shi, Guo-Hui Xing, Ping Xie, Na Zhao, Yu-Feng Yin, Shu-Yan Sun, Jing He, Ying Wang, Shi-Ying Xuan
J. Cancer 2017; 8(5): 801-808. doi:10.7150/jca.17640
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Albumin-to-Alkaline Phosphatase Ratio: A Novel Prognostic Index of Overall Survival in Cisplatin-based Chemotherapy-treated Patients with Metastatic Nasopharyngeal Carcinoma
Man Nie, Peng Sun, Cui Chen, Xiwen Bi, Yu Wang, Hang Yang, Panpan Liu, Zhiming Li, Yi Xia, Wenqi Jiang
J. Cancer 2017; 8(5): 809-815. doi:10.7150/jca.17536
[Abstract] [Full text] [PDF] [PubMed] [PMC]

B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway
Yuchao Li, Guoning Guo, Jie Song, Zhiping Cai, Jin Yang, Zhiwen Chen, Yun Wang, Yaqin Huang, Qiangguo Gao
J. Cancer 2017; 8(5): 816-824. doi:10.7150/jca.17759
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Class I versus Class III radical hysterectomy in stage IB1 (tumor ≤ 2 cm) cervical cancer: a matched cohort study
Wei Wang, Chun-liang Shang, Qi-qiao Du, Di Wu, Yan-chun Liang, Tian-yu Liu, Jia-ming Huang, Shu-zhong Yao
J. Cancer 2017; 8(5): 825-831. doi:10.7150/jca.17663
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Vicious circle of acute radiation toxicities and weight loss predicts poor prognosis for nasopharyngeal carcinoma patients receiving intensity modulated radiotherapy
Guo Li, Xiong-ying Jiang, Bo Qiu, Lu-Jun Shen, Chen Chen, Yun-Fei Xia
J. Cancer 2017; 8(5): 832-838. doi:10.7150/jca.17458
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Gambogenic acid synergistically potentiates bortezomib-induced apoptosis in multiple myeloma
Runzhe Chen, Hongming Zhang, Ping Liu, Xue Wu, Baoan Chen
J. Cancer 2017; 8(5): 839-851. doi:10.7150/jca.17657
[Abstract] [Full text] [PDF] [PubMed] [PMC]

NR1H3 Expression is a Prognostic Factor of Overall Survival for Patients with Muscle-Invasive Bladder Cancer
Junlong Wu, Fangning Wan, Haoyue Sheng, Guohai Shi, Yijun Shen, Guowen Lin, Bo Dai, Yiping Zhu, Dingwei Ye
J. Cancer 2017; 8(5): 852-860. doi:10.7150/jca.17845
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Magnetic Resonance Imaging-Detected Tumor Residue after Intensity-Modulated Radiation Therapy and its Association with Post-Radiation Plasma Epstein-Barr Virus Deoxyribonucleic Acid in Nasopharyngeal Carcinoma
Jia-Wei Lv, Guan-Qun Zhou, Jia-Xiang Li, Ling-Long Tang, Yan-Ping Mao, Ai-Hua Lin, Jun Ma, Ying Sun
J. Cancer 2017; 8(5): 861-869. doi:10.7150/jca.17957
[Abstract] [Full text] [PDF] [PubMed] [PMC]

MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of LKB1/PTEN/CDKN1A
Chunmei Li, Jianxin Lyu, Qing H. Meng
J. Cancer 2017; 8(5): 870-879. doi:10.7150/jca.17958
[Abstract] [Full text] [PDF] [PubMed] [PMC]

CT120: A New Potential Target for c-Myc in Head and Neck Cancers
Elif Baltaci, Betül Seyhan, Onur Baykara, Nur Buyru
J. Cancer 2017; 8(5): 880-886. doi:10.7150/jca.18207
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Aided Diagnosis of Hepatocellular Carcinoma Using Serum Fucosylated Haptoglobin Ratios
Shuxin Shang, Wei Li, Xue Qin, Shu Zhang, Yinkun Liu
J. Cancer 2017; 8(5): 887-893. doi:10.7150/jca.17747
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Increased TET1 Expression in Inflammatory Microenvironment of Hyperinsulinemia Enhances the Response of Endometrial Cancer to Estrogen by Epigenetic Modulation of GPER
Qiao-Ying Lv, Bing-Ying Xie, Bing-Yi Yang, Cheng-Cheng Ning, Wei-Wei Shan, Chao Gu, Xue-Zhen Luo, Xiao-Jun Chen, Zhen-Bo Zhang, You-Ji Feng
J. Cancer 2017; 8(5): 894-902. doi:10.7150/jca.17064
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution
Ainur Sharip, Diyora Abdukhakimova, Xiao Wang, Alexey Kim, Yevgeniy Kim, Aigul Sharip, Askarbek Orakov, Lixia Miao, Qinglei Sun, Yue Chen, Zhenbang Chen, Yingqiu Xie
J. Cancer 2017; 8(5): 903-912. doi:10.7150/jca.17961
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression
Anna Tyutyunnykova, Gennady Telegeev, Anna Dubrovska
J. Cancer 2017; 8(5): 716-729. doi:10.7150/jca.17779
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Role of tumor microenvironment in tumorigenesis
Maonan Wang, Jingzhou Zhao, Lishen Zhang, Fang Wei, Yu Lian, Yingfeng Wu, Zhaojian Gong, Shanshan Zhang, Jianda Zhou, Ke Cao, Xiayu Li, Wei Xiong, Guiyuan Li, Zhaoyang Zeng, Can Guo
J. Cancer 2017; 8(5): 761-773. doi:10.7150/jca.17648
[Abstract] [Full text] [PDF] [PubMed] [PMC]