J Cancer 2011; 2:339-340. doi:10.7150/jca.2.339

Short Report

Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft

Fabio Ciceri, Marco Bregni, Jacopo Peccatori

Hematology and BMT Unit, Department of Oncology, San Raffaele Scientific Institute, Milano, Italy

Abstract

We exploited the dual positive effects of rapamycin to prevent GvHD and control malignant cells upon infusion of unmanipulated grafts from family haploidentical donors to patients affected by advanced hematological malignancies. Preliminary results on 45 patients show the feasibility of this platform with an appreciable low rate of GvHD.

Keywords: Stem Cell Transplantation, Haploidentical, Donor Graft

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How to cite this article:
Ciceri F, Bregni M, Peccatori J. Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft. J Cancer 2011; 2:339-340. doi:10.7150/jca.2.339. Available from http://www.jcancer.org/v02p0339.htm