A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer

Ohtani, Hiroshi; Tamamori, Yutaka; Arimoto, Yuichi; Nishiguchi, Yukio; Maeda, Kiyoshi; Hirakawa, Kosei

doi:10.7150/jca.2.425

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J Cancer 2011; 2:425-434. doi:10.7150/jca.2.425 This volume Cite

Research Paper

A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer

Hiroshi Ohtani^1✉, Yutaka Tamamori¹, Yuichi Arimoto¹, Yukio Nishiguchi², Kiyoshi Maeda³, Kosei Hirakawa³

1. Department of Surgery, Osaka City Sumiyoshi Hospital
2. Department of Surgery, Osaka City General Hospital
3. Department of Surgical Oncology, Osaka City University Graduate School of Medicine

Citation:

Ohtani H, Tamamori Y, Arimoto Y, Nishiguchi Y, Maeda K, Hirakawa K. A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer. J Cancer 2011; 2:425-434. doi:10.7150/jca.2.425. https://www.jcancer.org/v02p0425.htm

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Abstract

Purpose: We conducted a meta-analysis to evaluate and compare the short- and long-term results of laparoscopic colorectal surgery (LCRS) and conventional open surgery (OCRS) for colorectal cancer (CRC).

Methods: We searched relevant papers published between January 1990 and May 2011. We analyzed the outcomes of each type of surgery over the short- and long-term periods.

Results: In the short-term period, we found no significant differences in overall perioperative complications and anastomotic leakage between LCRS and OCRS groups. We found no significant differences in overall, distant, local and wound-site recurrence, overall mortality, 3 and 5 year disease-free survival rate, and cancer-related mortality between the 2 groups.

Conclusions: LCRS has the benefits of reducing intraoperative blood loss, earlier resumption of oral intake, and shorter duration of hospital stay in the short-term. The long-term outcomes of LCRS seem to be similar to those of OCRS.

Keywords: meta-analysis, laparoscopy-assisted colorectal surgery, colorectal cancer

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APA

Ohtani, H., Tamamori, Y., Arimoto, Y., Nishiguchi, Y., Maeda, K., Hirakawa, K. (2011). A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer. Journal of Cancer, 2, 425-434. https://doi.org/10.7150/jca.2.425.

ACS

Ohtani, H.; Tamamori, Y.; Arimoto, Y.; Nishiguchi, Y.; Maeda, K.; Hirakawa, K. A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer. J. Cancer 2011, 2, 425-434. DOI: 10.7150/jca.2.425.

NLM

CSE

Ohtani H, Tamamori Y, Arimoto Y, Nishiguchi Y, Maeda K, Hirakawa K. 2011. A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer. J Cancer. 2:425-434.

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