Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are <i>BRCA</i>-Negative

Elsayegh, Nisreen; Profato, Jessica; Barrera, Angelica M. Gutierrez; Lin, Heather; Kuerer, Henry M.; Ardic, Can; Litton, Jennifer K.; Tripathy, Debasish; Arun, Banu K.

doi:10.7150/jca.11710

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J Cancer 2015; 6(7):610-615. doi:10.7150/jca.11710 This issue Cite

Research Paper

Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative

Nisreen Elsayegh¹, Jessica Profato¹, Angelica M. Gutierrez Barrera², Heather Lin³, Henry M. Kuerer⁴, Can Ardic², Jennifer K. Litton², Debasish Tripathy², Banu K. Arun^{1,2 ✉}

1. Clinical Cancer Genetics, the University of Texas MD Anderson Cancer Center, Houston, TX
2. Department of Breast Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX
3. Department of Biostatistics, the University of Texas MD Anderson Cancer Center, Houston, TX
4. Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX

Citation:

Elsayegh N, Profato J, Barrera AMG, Lin H, Kuerer HM, Ardic C, Litton JK, Tripathy D, Arun BK. Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative. J Cancer 2015; 6(7):610-615. doi:10.7150/jca.11710. https://www.jcancer.org/v06p0610.htm

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Abstract

The authors retrospectively examined the contralateral prophylactic mastectomy (CPM) rate among 100 women with ductal carcinoma in situ who are BRCA negative. Of 100 women with ductal carcinoma in situ, 31 elected contralateral prophylactic mastectomy (CPM). Factors associated with increased likelihood of undergoing contralateral prophylactic mastectomy (CPM) among this cohort were: family history of ovarian cancer, marital status, reconstruction, mastectomy of the affected breast, and tamoxifen use.

Keywords: contralateral prophylactic mastectomy, BRCA negative

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APA

Elsayegh, N., Profato, J., Barrera, A.M.G., Lin, H., Kuerer, H.M., Ardic, C., Litton, J.K., Tripathy, D., Arun, B.K. (2015). Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative. Journal of Cancer, 6(7), 610-615. https://doi.org/10.7150/jca.11710.

ACS

Elsayegh, N.; Profato, J.; Barrera, A.M.G.; Lin, H.; Kuerer, H.M.; Ardic, C.; Litton, J.K.; Tripathy, D.; Arun, B.K. Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative. J. Cancer 2015, 6 (7), 610-615. DOI: 10.7150/jca.11710.

NLM

CSE

Elsayegh N, Profato J, Barrera AMG, Lin H, Kuerer HM, Ardic C, Litton JK, Tripathy D, Arun BK. 2015. Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative. J Cancer. 6(7):610-615.

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