J Cancer 2019; 10(3):765-771. doi:10.7150/jca.30494

Research Paper

Can high school students help to improve breast radiologists in detecting missed breast cancer lesions on full-field digital mammography?

T.J.A. van Nijnatten 1,2,3*✉, M.L. Smidt2,3*, B. Goorts1,2,3, S. Samiei1,2,3, I. Houben1, E.M. Kok4, J.E. Wildberger1, S.G.F. Robben1, M.B.I. Lobbes1,3

1. Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, the Netherlands.
2. Department of Surgery, Maastricht University Medical Center+, Maastricht, the Netherlands.
3. GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands.
4. School of Health Professions Education, Department of Education Research and Development, Maastricht University Medical Center+, Maastricht, the Netherlands.
*Both authors contributed equally to this work

Abstract

Aim: To investigate whether full-field digital mammography (FFDM) and contrast-enhanced mammography (CEM), evaluated by non-experienced high school students, improves detection of missed breast cancer lesions on FFDM, in the same cohort of patients.

Methods: Non-experienced first- and second year high school students examined fourteen cases of patients diagnosed with breast cancer. These cases consisted of missed breast cancer lesions on FFDM by a breast radiologist. Sensitivity of assessment of the students on FFDM and CEM was analysed and compared with the initial results of the breast radiologists.

Results: A total of 134 high school students participated in this study. Mean age was 12.8 years (range 10-14). Based on FFDM, mean overall sensitivity of the students was 29.2% (18.9 - 39.6%). When recombined CEM images were used, mean overall sensitivity of students improved to 82.6% (74.0 - 91.2%) (p=0.001). Mean overall sensitivity of FFDM exams evaluated by radiologists was 75.7% (64.2 - 87.3%), which was lower when compared to student's evaluations on recombined CEM exams, yet not statistically significant (p=0.098).

Conclusions: Contrast-enhanced mammography evaluated by non-experienced high school students might improve detection rate of breast cancer when compared to evaluations of only full-field digital mammography by radiologists.

Keywords: mammography, contrast-enhanced mammography, breast cancer, sensitivity, students

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
van Nijnatten TJA, Smidt ML, Goorts B, Samiei S, Houben I, Kok EM, Wildberger JE, Robben SGF, Lobbes MBI. Can high school students help to improve breast radiologists in detecting missed breast cancer lesions on full-field digital mammography?. J Cancer 2019; 10(3):765-771. doi:10.7150/jca.30494. Available from http://www.jcancer.org/v10p0765.htm