J Cancer
2023; 14(17):3203-3213.
doi:10.7150/jca.86967 This issueCite
Review
Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma
Bai Ding1*, Yinghui Song2*, Sulai Liu1,2, Chuang Peng1✉, Yujing Zhang2,3✉
1. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, China 2. Central Laboratory of Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410015, China. 3. Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China. *Contributed equally.
✉ Corresponding authors: Professor Chuang Peng, Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University); 61 Jiefang Road, Changsha, Hunan 410005, P.R. China. Professor Yujing Zhang, Central Laboratory of Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410015, China.Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China. E-mail: pengchuangcncom; E-mail: zhangyujingedu.cn.More
Citation:
Ding B, Song Y, Liu S, Peng C, Zhang Y. Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma. J Cancer 2023; 14(17):3203-3213. doi:10.7150/jca.86967. https://www.jcancer.org/v14p3203.htm
Cholangiocarcinoma (CCA) is the most recurrent malignant tumor found in the biliary system. It originates from the bile duct epithelial cells characterized by easy metastasis, high intermittent rate, and poor prognosis. Acetaldehyde dehydrogenase 1 (ALDH1), a marker of cancer stem cells, the levels of which are particularly elevated in various of malignant tumors. Additionally, the increased ALDH1 levels are closely related to the degree and prognosis of malignant tumors. This study reviewed the mechanisms underlying the changes in ALDH1 levels in CCA.
Keywords: Cholangiocarcinoma, ALDH1, prognosis
Citation styles
APA
Ding, B., Song, Y., Liu, S., Peng, C., Zhang, Y. (2023). Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma. Journal of Cancer, 14(17), 3203-3213. https://doi.org/10.7150/jca.86967.
ACS
Ding, B.; Song, Y.; Liu, S.; Peng, C.; Zhang, Y. Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma. J. Cancer 2023, 14 (17), 3203-3213. DOI: 10.7150/jca.86967.
NLM
Ding B, Song Y, Liu S, Peng C, Zhang Y. Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma. J Cancer 2023; 14(17):3203-3213. doi:10.7150/jca.86967. https://www.jcancer.org/v14p3203.htm
CSE
Ding B, Song Y, Liu S, Peng C, Zhang Y. 2023. Mechanisms underlying the changes in acetaldehyde dehydrogenase 1 in cholangiocarcinoma. J Cancer. 14(17):3203-3213.
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