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Volume 6 (12); 2015

Research Paper

Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma
Florian Ewald, Dominik Nörz, Astrid Grottke, Johanna Bach, Christiane Herzberger, Bianca T. Hofmann, Björn Nashan, Manfred Jücker
J. Cancer 2015; 6(12): 1195-1205. doi:10.7150/jca.12452
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Expression Profiling Identifies Bezafibrate as Potential Therapeutic Drug for Lung Adenocarcinoma
Xinyan Liu, Xiaoqin Yang, Xinmei Chen, Yantao Zhang, Xuebin Pan, Guiping Wang, Yun Ye
J. Cancer 2015; 6(12): 1214-1221. doi:10.7150/jca.12191
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Expression of CD9 and PIK3CD is Associated with Prognosis of Follicular Lymphoma
Tieying Dong, Zhaoliang Liu, Shu Zhao, Chengyi Hu, Yupeng Liu, WenJie Ma, Qingyuan Zhang
J. Cancer 2015; 6(12): 1222-1229. doi:10.7150/jca.11279
[Abstract] [Full text] [PDF] [PubMed] [PMC]

MicroRNA-222 Controls Human Pancreatic Cancer Cell Line Capan-2 Proliferation by P57 Targeting
Yingying Zhao, Yuqiong Wang, Yuefeng Yang, Jingqi Liu, Yang Song, Yan Cao, Xiaoyu Chen, Wenzhuo Yang, Fei Wang, Jun Gao, Zhaoshen Li, Changqing Yang
J. Cancer 2015; 6(12): 1230-1235. doi:10.7150/jca.12546
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Fraction of CD133+ CNE2 Cells Is Made of Giant Cancer Cells with Morphological Evidence of Asymmetric Mitosis
Qingping Jiang, Qianbing Zhang, Shuang Wang, Siming Xie, Weiyi Fang, Zhen Liu, Jinsong Liu, Kaitai Yao
J. Cancer 2015; 6(12): 1236-1244. doi:10.7150/jca.12626
[Abstract] [Full text] [PDF] [PubMed] [PMC]

High Expression of FGFR4 Enhances Tumor Growth and Metastasis in Nasopharyngeal Carcinoma
Si Shi, Xingyu Li, Bo You, Ying Shan, Xiaolei Cao, Yiwen You
J. Cancer 2015; 6(12): 1245-1254. doi:10.7150/jca.12825
[Abstract] [Full text] [PDF] [PubMed] [PMC]

CT120A Acts as an Oncogene in Head and Neck Squamous Cell Carcinoma
Elif Baltaci, Seda Ekizoglu, Elif Sari, Emin Karaman, Turgut Ulutin, Nur Buyru
J. Cancer 2015; 6(12): 1255-1259. doi:10.7150/jca.12969
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Hsa-miR-301a-3p Acts as an Oncogene in Laryngeal Squamous Cell Carcinoma via Target Regulation of Smad4
Yan Lu, Wei Gao, Chunming Zhang, Shuxin Wen, Hui Huangfu, Jian Kang, Binquan Wang
J. Cancer 2015; 6(12): 1260-1275. doi:10.7150/jca.12659
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Serum Unsaturated Free Fatty Acids: A Potential Biomarker Panel for Differentiating Benign Thyroid Diseases from Thyroid Cancer
Yaping Zhang, Ling Qiu, Chengyan He, Yanmin Wang, Yujie liu, Dan Zhang, Zhili Li
J. Cancer 2015; 6(12): 1276-1281. doi:10.7150/jca.12433
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Novel Treatment Method for Lymph Node Metastasis Using a Lymphatic Drug Delivery System with Nano/Microbubbles and Ultrasound
Shigeki Kato, Shiro Mori, Tetsuya Kodama
J. Cancer 2015; 6(12): 1282-1294. doi:10.7150/jca.13028
[Abstract] [Full text] [PDF] [PubMed] [PMC]

MiR-182 Is Associated with Growth, Migration and Invasion in Prostate Cancer via Suppression of FOXO1
Christopher J.D. Wallis, Aida Gordanpour, Jessica Stojcic Bendavid, Linda Sugar, Robert K. Nam, Arun Seth
J. Cancer 2015; 6(12): 1295-1305. doi:10.7150/jca.13176
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Comprehensive Two- and Three-Dimensional RNAi Screening Identifies PI3K Inhibition as a Complement to MEK Inhibitor AS703026 for Combination Treatment of Triple-Negative Breast Cancer
Jangsoon Lee, Rachael Galloway, Geoff Grandjean, Justin Jacob, Juliane Humphries, Chandra Bartholomeusz, Samantha Goodstal, Bora Lim, Geoffrey Bartholomeusz, Naoto T. Ueno, Arvind Rao
J. Cancer 2015; 6(12): 1306-1319. doi:10.7150/jca.13266
[Abstract] [Full text] [PDF] [PubMed] [PMC]

PLX4032 Mediated Melanoma Associated Antigen Potentiation in Patient Derived Primary Melanoma Cells
Andrea L. George, Robert Suriano, Shilpi Rajoria, Maria C. Osso, Neha Tuli, Elyse Hanly, Jan Geliebter, Angelo N. Arnold, Marc Wallack, Raj K. Tiwari
J. Cancer 2015; 6(12): 1320-1330. doi:10.7150/jca.11126
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Low Dose, Low Cost Estradiol Pellets Can Support MCF-7 Tumour Growth in Nude Mice without Bladder Symptoms
Genevieve Dall, Jessica Vieusseux, Ashleigh Unsworth, Robin Anderson, Kara Britt
J. Cancer 2015; 6(12): 1331-1336. doi:10.7150/jca.10890
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Knockdown of hTERT and Treatment with BIBR1532 Inhibit Cell Proliferation and Invasion in Endometrial Cancer Cells
Weimin Kong, Nenan Lv, Weiya Z. Wysham, Dario R. Roque, Tongqing Zhang, Simeng Jiao, Dan Song, Jiao Chen, Victoria L. Bae-Jump, Chunxiao Zhou
J. Cancer 2015; 6(12): 1337-1345. doi:10.7150/jca.13054
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Identification of Regulatory-RNAs for Alternative Splicing of Ron Proto-Oncogene
Heegyum Moon, Xuexiu Zheng, Tiing Jen Loh, Ha Na Jang, Yongchao Liu, Da-Woon Jung, Darren R Williams, Haihong Shen
J. Cancer 2015; 6(12): 1346-1351. doi:10.7150/jca.13361
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

May Circulating microRNAs be Gastric Cancer Diagnostic Biomarkers?
Xiaoling Wu, Xiaohui Tan, Sidney W. Fu
J. Cancer 2015; 6(12): 1206-1213. doi:10.7150/jca.12535
[Abstract] [Full text] [PDF] [PubMed] [PMC]