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Volume 8 (14); 2017

Research Paper

The Influence of Prednisone on the Efficacy of Cabazitaxel in Men with Metastatic Castration-Resistant Prostate Cancer
Carlo Buonerba, Guru Sonpavde, Francesca Vitrone, Davide Bosso, Livio Puglia, Michela Izzo, Simona Iaccarino, Luca Scafuri, Margherita Muratore, Francesca Foschini, Brigitta Mucci, Vincenzo Tortora, Martina Pagliuca, Dario Ribera, Vittorio Riccio, Rocco Morra, Mirta Mosca, Nicola Cesarano, Ileana Di Costanzo, Sabino De Placido, Giuseppe Di Lorenzo
J. Cancer 2017; 8(14): 2663-2668. doi:10.7150/jca.20040
[Abstract] [Full text] [PDF] [PubMed] [PMC]

B-cell translocation gene 1 is downregulated by promoter methylation in ovarian carcinoma
Ji-Ye Kim, Sung-Im Do, Go Eun Bae, Hyun-Soo Kim
J. Cancer 2017; 8(14): 2669-2675. doi:10.7150/jca.21037
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Association between extranodal natural killer/T-cell lymphoma and hepatitis B viral infection: a case-control study
Kefeng Wang, Hang Yang, Wenjun He, Yi Xia, Zhongjun Xia, Su Li, Huiqiang Huang, Zhiming Li, Panpan Liu, Wenqi Jiang
J. Cancer 2017; 8(14): 2676-2683. doi:10.7150/jca.19665
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Updated Nomogram Incorporating Percentage of Positive Cores to Predict Probability of Lymph Node Invasion in Prostate Cancer Patients Undergoing Sentinel Lymph Node Dissection
Alexander Winter, Thomas Kneib, Clara Wasylow, Lena Reinhardt, Rolf-Peter Henke, Svenja Engels, Holger Gerullis, Friedhelm Wawroschek
J. Cancer 2017; 8(14): 2692-2698. doi:10.7150/jca.20409
[Abstract] [Full text] [PDF] [PubMed] [PMC]

IDH1 R132H Mutation Is Accompanied with Malignant Progression of Paired Primary-Recurrent Astrocytic Tumours
Luyan Mu, Wanzhen Xu, Qingla Li, Haitao Ge, Hongbo Bao, Songsong Xia, Jingjing Ji, Jie Jiang, Yuwen Song, Qiang Gao
J. Cancer 2017; 8(14): 2704-2712. doi:10.7150/jca.20665
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Impact of Cetuximab Plus AKT- or mTOR- Inhibitor in a Patient-Derived Colon Cancer Cell Model with Wild-Type RAS and PIK3CA Mutation
Ju Sun Kim, Jung Eun Kim, Kyung Kim, Jeeyun Lee, Joon Oh Park, Ho Yeong Lim, Young Suk Park, Won Ki Kang, Seung Tae Kim
J. Cancer 2017; 8(14): 2713-2719. doi:10.7150/jca.19458
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Down-regulation of RPS9 Inhibits Osteosarcoma Cell Growth through Inactivation of MAPK Signaling Pathway
Dong-dong Cheng, Bin Zhu, Shi-jie Li, Ting Yuan, Qing-cheng Yang, Cun-yi Fan
J. Cancer 2017; 8(14): 2720-2728. doi:10.7150/jca.19130
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Discovering the miR-26a-5p Targetome in Prostate Cancer Cells
Milena Rizzo, Gabriele Berti, Francesco Russo, Sofia Fazio, Monica Evangelista, Romina D'Aurizio, Marco Pellegrini, Giuseppe Rainaldi
J. Cancer 2017; 8(14): 2729-2739. doi:10.7150/jca.18396
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Microarray Analysis of the Expression Profile of Long Non-Coding RNAs Indicates lncRNA RP11-263F15.1 as a Biomarker for Diagnosis and Prognostic Prediction of Pancreatic Ductal Adenocarcinoma
Xiaoyi Huang, Na Ta, Yunshuo Zhang, Yisha Gao, Ronglei Hu, Lulu Deng, Bingbing Zhang, Hui Jiang, Jianming Zheng
J. Cancer 2017; 8(14): 2740-2755. doi:10.7150/jca.18073
[Abstract] [Full text] [PDF] [PubMed] [PMC]

High Immunoreactivity of DUOX2 Is Associated With Poor Response to Preoperative Chemoradiation Therapy and Worse Prognosis in Rectal Cancers
Shih-Chun Lin, I-Wei Chang, Pei-Ling Hsieh, Ching-Yih Lin, Ding-Ping Sun, Ming-Jen Sheu, Ching-Chieh Yang, Li-Ching Lin, Hong-Lin He, Yu-Feng Tian
J. Cancer 2017; 8(14): 2756-2764. doi:10.7150/jca.19545
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Refining the American Joint Committee on Cancer Staging Scheme For Resectable Pancreatic Ductal Adenocarcinoma Using Recursive Partitioning Analysis
Yiquan Jiang, Yanhong Su, Yutong Chen, Zhiyong Li
J. Cancer 2017; 8(14): 2765-2773. doi:10.7150/jca.19515
[Abstract] [Full text] [PDF] [PubMed] [PMC]

CT-721, a Potent Bcr-Abl Inhibitor, Exhibits Excellent In Vitro and In Vivo Efficacy in the Treatment of Chronic Myeloid Leukemia
Yinghui Sun, Na Zhao, Huan Wang, Qiong Wu, Yunqi Han, Qichao Liu, Mangang Wu, Yuliang Liu, Fansheng Kong, He Wang, Ying Sun, Deguang Sun, Lutao Jing, Guojing Tang, Yuandong Hu, Dengming Xiao, Hong Luo, Yongxin Han, Yong Peng
J. Cancer 2017; 8(14): 2774-2784. doi:10.7150/jca.18731
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Loss of β-arrestin-2 and Activation of CXCR2 Correlate with Lymph Node Metastasis in Non-small Cell Lung Cancer
Lei Cong, Zhi-yong Qiu, Yang Zhao, Wei-bo Wang, Cai-xia Wang, Hong-chang Shen, Jun-qing Han
J. Cancer 2017; 8(14): 2785-2792. doi:10.7150/jca.19631
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Villi-specific Gene Expression Reveals Novel Prognostic Biomarkers in Multiple Human Cancers
Botao Zhang, Lin Feng, Honglin Guo, Hongxia Li, Yuanjing Wang, Kaitai Zhang, Xuexin Yu, Shujun Cheng
J. Cancer 2017; 8(14): 2793-2801. doi:10.7150/jca.19787
[Abstract] [Full text] [PDF] [PubMed] [PMC]

HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins
Lei Sun, Jia Ke, Zhen He, Zexian Chen, Qinghua Huang, Wenjia Ai, Guoqiang Wang, Yisheng Wei, Xiangcai Zou, Shi Zhang, Ping Lan, Chuyuan Hong
J. Cancer 2017; 8(14): 2802-2808. doi:10.7150/jca.19142
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Impact of Microsatellite Instability Status and Sidedness of the Primary Tumor on the Effect of Cetuximab-Containing Chemotherapy in Patients with Metastatic Colorectal Cancer
Seung Tae Kim, Su-Jin Lee, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park
J. Cancer 2017; 8(14): 2809-2815. doi:10.7150/jca.18286
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Twisted Gastrulation BMP Signaling Modulator 1 Regulates Papillary Thyroid Cancer Cell Motility and Proliferation
Shujun Xia, Ri Ji, Yongmin Xu, Xiaofeng Ni, Yijie Dong, Weiwei Zhan
J. Cancer 2017; 8(14): 2816-2827. doi:10.7150/jca.18482
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognostic Impact of ABO Blood Group on Type I Endometrial Cancer Patients- Results from Our Own and Other Studies
Vincenzo Dario Mandato, Federica Torricelli, Valentina Mastrofilippo, Gino Ciarlini, Debora Pirillo, Enrico Farnetti, Loretta Fornaciari, Bruno Casali, Maria Carolina Gelli, Martino Abrate, Lorenzo Aguzzoli, Giovanni Battista La Sala, Davide Nicoli
J. Cancer 2017; 8(14): 2828-2835. doi:10.7150/jca.19524
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Who benefited most from higher cumulative dose of cisplatin among patients with locally advanced nasopharyngeal carcinoma treated by intensity-modulated radiation therapy? A retrospective study of 527 cases
Xiaomin Ou, Tingting Xu, Xiayun He, Hongmei Ying, Chaosu Hu
J. Cancer 2017; 8(14): 2836-2845. doi:10.7150/jca.19725
[Abstract] [Full text] [PDF] [PubMed] [PMC]

ERCC1_202 Is A Prognostic Biomarker in Advanced Stage Non-Small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy
Xiyong Wang, Xiaoli Zhu, Hongming Zhang, Xiaobo Fan, Xiulei Xue, Yan Chen, Chenbo Ding, Jianwen Zhao, Guoqiu Wu
J. Cancer 2017; 8(14): 2846-2853. doi:10.7150/jca.19897
[Abstract] [Full text] [PDF] [PubMed] [PMC]

MicroRNA-216b-5p Functions as a Tumor-suppressive RNA by Targeting TPT1 in Pancreatic Cancer Cells
Yu You, Jiaxin Tan, Yi Gong, Haisu Dai, Haowei Chen, Xuejun Xu, Aigang Yang, Yujun Zhang, Ping Bie
J. Cancer 2017; 8(14): 2854-2865. doi:10.7150/jca.18931
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype
Cinthya Gurrion, Maritere Uriostegui, Mario Zurita
J. Cancer 2017; 8(14): 2866-2875. doi:10.7150/jca.19477
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Evaluation Analysis of miRNAs Overexpression in Liquid-Based Cytology Endometrial Samples
Christine Kottaridi, Aris Spathis, Niki Margari, Nikolaos Koureas, Emmanouil Terzakis, Charalampos Chrelias, Asimakis Pappas, Evripidis Bilirakis, Abraham Pouliakis, Ioannis J Panayiotides, Petros Karakitsos
J. Cancer 2017; 8(14): 2699-2703. doi:10.7150/jca.19947
[Abstract] [Full text] [PDF] [PubMed] [PMC]


DCIS Margins and Breast Conservation: MD Anderson Cancer Center Multidisciplinary Practice Guidelines and Outcomes
Henry M. Kuerer, Benjamin D. Smith, Mariana Chavez-MacGregor, Constance Albarracin, Carlos H. Barcenas, Lumarie Santiago, Mary E. Edgerton, Gaiane M. Rauch, Sharon H. Giordano, Aysegul Sahin, Savitri Krishnamurthy, Wendy Woodward, Debasish Tripathy, Wei T. Yang, Kelly K. Hunt
J. Cancer 2017; 8(14): 2653-2662. doi:10.7150/jca.20871
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Putative Role of TP53 Alterations and p53 Expression in Borderline Ovarian Tumors - Correlation with Clinicopathological Features and Prognosis: A Mini-Review
Andrzej Semczuk, Marek Gogacz, Anna Semczuk-Sikora, Maciej Jóźwik, Tomasz Rechberger
J. Cancer 2017; 8(14): 2684-2691. doi:10.7150/jca.19691
[Abstract] [Full text] [PDF] [PubMed] [PMC]