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Volume 8 (18); 2017

Research Paper

MCMs expression in lung cancer: implication of prognostic significance
Yi-Zhen Liu, Bo-Shi Wang, Yan-Yi Jiang, Jian Cao, Jia-Jie Hao, Yu Zhang, Xin Xu, Yan Cai, Ming-Rong Wang
J. Cancer 2017; 8(18): 3641-3647. doi:10.7150/jca.20777
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer
Kalliopi Domvri, Konstantinos Zarogoulidis, Nikolaos Ziogas, Paul Zarogoulidis, Savvas Petanidis, Konstantinos Porpodis, Efrosini Kioseoglou, Wolfgang Hohenforst-Schmidt
J. Cancer 2017; 8(18): 3648-3656. doi:10.7150/jca.21783
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Phase II Randomized Controlled Trial: Definitive Concurrent Chemoradiotherapy with Docetaxel Plus Cisplatin versus 5-Fluorouracil plus Cisplatin in Patients with Oesophageal Squamous Cell Carcinoma
Yujia Zhu, Wenwen Zhang, Qiaoqiao Li, Qiwen Li, Bo Qiu, Hui Liu, Mengzhong Liu, Yonghong Hu
J. Cancer 2017; 8(18): 3657-3666. doi:10.7150/jca.20053
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Cpt1c regulated by AMPK promotes papillary thyroid carcinomas cells survival under metabolic stress conditions
Rui Wang, Yajun Cheng, Dongwei Su, Boshen Gong, Xiaobo He, Xinyu Zhou, Zhijun Pang, Lingtao Cheng, Yuelei Chen, Zhenzhen Yao
J. Cancer 2017; 8(18): 3675-3681. doi:10.7150/jca.21148
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Continuation of Tyrosine Kinase Inhibitor is Associated with Survival Benefit in NSCLC Patients with Exon 19 Deletion after Solitary Progression
Feifei Na, Jie Zhang, Lei Deng, Xiaojuan Zhou, Lin Zhou, Bingwen Zou, Min Yu, Yanying Li, Jianxin Xue, Yongmei Liu
J. Cancer 2017; 8(18): 3682-3688. doi:10.7150/jca.20017
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Curcumin Enhances the Anticancer Effect Of 5-fluorouracil against Gastric Cancer through Down-Regulation of COX-2 and NF- κB Signaling Pathways
Hongru Yang, Shaoqiu Huang, Yumeng Wei, Shousong Cao, Chao Pi, Ting Feng, Jing Liang, Ling Zhao, Guosheng Ren
J. Cancer 2017; 8(18): 3697-3706. doi:10.7150/jca.20196
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Tahir Mehmood, Amara Maryam, Xiangge Tian, Muhammad Khan, Tonghui Ma
J. Cancer 2017; 8(18): 3707-3717. doi:10.7150/jca.20239
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Survival and Toxicities of IMRT Based on the RTOG Protocols in Patients with Nasopharyngeal Carcinoma from the Endemic Regions of China
Shao-Bo Liang, Yan Wang, Xue-Feng Hu, Sha-Sha He, Xing-Li Yang, Li-Zhi Liu, Chun-Yan Cui, Yong Chen, Li-Wu Fu
J. Cancer 2017; 8(18): 3718-3724. doi:10.7150/jca.20351
[Abstract] [Full text] [PDF] [PubMed] [PMC]

R.E.N.A.L. Nephrometry Score: A Preoperative Risk Factor Predicting the Fuhrman Grade of Clear-Cell Renal Carcinoma
Shao-Hao Chen, Yu-Peng Wu, Xiao-Dong Li, Tian Lin, Qing-Yong Guo, Ye-Hui Chen, Jin-Bei Huang, Yong Wei, Xue-Yi Xue, Qing-Shui Zheng, Ning Xu
J. Cancer 2017; 8(18): 3725-3732. doi:10.7150/jca.21189
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer
Le Chen, Ying Yao, Lijuan Sun, Jie Tang
J. Cancer 2017; 8(18): 3733-3741. doi:10.7150/jca.20814
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Insufficient Radiofrequency Ablation Treated Hepatocellular Carcinoma Cells Promote Metastasis by Up-Regulation ITGB3
Ning Zhang, Dening Ma, Lu Wang, Xiaodong Zhu, Qi Pan, Yiming Zhao, Weiping Zhu, Jiamin Zhou, Longrong Wang, Zongtao Chai, Jianyang Ao, Huichuan Sun, Zhaoyou Tang
J. Cancer 2017; 8(18): 3742-3754. doi:10.7150/jca.20816
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A nomogram based on phosphorylated AKT1 for predicting locoregional recurrence in patients with oesophageal squamous cell carcinoma
Weiwei Yu, Li Chu, Kuaile Zhao, Haiquan Chen, Jiaqing Xiang, Yawei Zhang, Hecheng Li, Weixin Zhao, Menghong Sun, Qiao Wei, Xiaolong Fu, Congying Xie, Zhengfei Zhu
J. Cancer 2017; 8(18): 3755-3763. doi:10.7150/jca.20828
[Abstract] [Full text] [PDF] [PubMed] [PMC]

ITGBL1 Predicts a Poor Prognosis and Correlates EMT Phenotype in Gastric Cancer
Rongkun Li, Chun Zhuang, Shuheng Jiang, Nan Du, Wenyi Zhao, Lin Tu, Hui Cao, Zhigang Zhang, Xiaofei Chen
J. Cancer 2017; 8(18): 3764-3773. doi:10.7150/jca.20900
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Combined Inhibitions of Glycolysis and AKT/autophagy Can Overcome Resistance to EGFR-targeted Therapy of Lung Cancer
Mingtong Ye, Sufan Wang, Ting Wan, Rui Jiang, Yun Qiu, Lei Pei, Nengzhi Pang, Yuanling Huang, Yufeng Huang, Zhenfeng Zhang, Lili Yang
J. Cancer 2017; 8(18): 3774-3784. doi:10.7150/jca.21035
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Polymorphisms of CCNB1 Associated With the Clinical Outcomes of Platinum-Based Chemotherapy in Chinese NSCLC Patients
Di Liu, Wen Xu, Xi Ding, Yang Yang, Bo Su, Ke Fei
J. Cancer 2017; 8(18): 3785-3794. doi:10.7150/jca.21151
[Abstract] [Full text] [PDF] [PubMed] [PMC]

New Clinical Features and Dosimetric Predictor Identification for Symptomatic Radiation Pneumonitis after Tangential Irradiation in Breast Cancer Patients
Ge Wen, Yu-Ting Tan, Xiao-Wen Lan, Zhi-Chun He, Jiang-Hua Huang, Jun-Tian Shi, Xiao Lin, Xiao-Bo Huang
J. Cancer 2017; 8(18): 3795-3802. doi:10.7150/jca.21158
[Abstract] [Full text] [PDF] [PubMed] [PMC]

LncRNA MALAT1 Inhibits Apoptosis and Promotes Invasion by Antagonizing miR-125b in Bladder Cancer Cells
Haibiao Xie, Xinhui Liao, Zhicong Chen, Yuan Fang, Anbang He, Yucheng Zhong, Qunjun Gao, Huizhong Xiao, Jianfa Li, Weiren Huang, Yuchen Liu
J. Cancer 2017; 8(18): 3803-3811. doi:10.7150/jca.21228
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma
Xu-Qiong Huang, Zi-Qi Zhou, Xiao-Fei Zhang, Chang-Long Chen, Yan Tang, Qian Zhu, Jian-Hua Zhang, Jian-Chuan Xia
J. Cancer 2017; 8(18): 3812-3827. doi:10.7150/jca.20775
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Ki67 Proliferation Index as a Histopathological Predictive and Prognostic Parameter of Oral Mucosal Melanoma in Patients without Distant Metastases
Xuhui Ma, Yunteng Wu, Tian Zhang, Hao Song, Houyu Jv, Wei Guo, Guoxin Ren
J. Cancer 2017; 8(18): 3828-3837. doi:10.7150/jca.20935
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Predictive and Prognostic Role of Stromal Tumor-infiltrating Lymphocytes in HER2-positive Breast Cancer with Trastuzumab-based Treatment: a Meta-analysis and Systematic Review
Tao Xu, Bang-Shun He, Xiang-Xiang Liu, Xiu-Xiu Hu, Kang Lin, Yu-Qin Pan, Hui-Ling Sun, Hong-Xin Peng, Xiao-Xiang Chen, Shu-Kui Wang
J. Cancer 2017; 8(18): 3838-3848. doi:10.7150/jca.21051
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Comparable Survival between Additional Radiotherapy and Local Surgery in Occult Breast Cancer after Axillary Lymph Node Dissection: A Population-based Analysis
San-Gang Wu, Wen-Wen Zhang, Jia-Yuan Sun, Feng-Yan Li, Huan-Xin Lin, Yong-Xiong Chen, Zhen-Yu He
J. Cancer 2017; 8(18): 3849-3855. doi:10.7150/jca.21217
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Preoperative Albumin-Bilirubin Score for Postoperative Solitary Hepatocellular Carcinoma within the Milan Criteria and Child-Pugh A Cirrhosis
Zhao-Ru Dong, Jie Zou, Dong Sun, Guo-Ming Shi, Ai-Wu Ke, Jia-Bin Cai, Hui-Chuan Sun, Shuang-Jian Qiu, Tao Li, Jian Zhou, Xu-Ting Zhi, Jia Fan
J. Cancer 2017; 8(18): 3862-3867. doi:10.7150/jca.21313
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Clinical Significance of CD163+ and CD68+ Tumor-associated Macrophages in High-risk HPV-related Cervical Cancer
Xiao-Jing Chen, Ling-Fei Han, Xiang-Guang Wu, Wen-Fei Wei, Lan-Fang Wu, Hong-Yan Yi, Rui-Ming Yan, Xiang-yang Bai, Mei Zhong, Yan-hong Yu, Li Liang, Wei Wang
J. Cancer 2017; 8(18): 3868-3875. doi:10.7150/jca.21444
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Aqueous Huaier Extract Suppresses Gastric Cancer Metastasis and Epithelial to Mesenchymal Transition by Targeting Twist
Zhiyuan Xu, Guowei Zheng, Yiping Wang, Chunli Zhang, Jianfa Yu, Fei Teng, Hang Lv, Xiangdong Cheng
J. Cancer 2017; 8(18): 3876-3886. doi:10.7150/jca.20380
[Abstract] [Full text] [PDF] [PubMed] [PMC]

PFKFB3 promotes proliferation, migration and angiogenesis in nasopharyngeal carcinoma
Miao Gu, Li Li, Zhenxin Zhang, Jing Chen, Wei Zhang, Jie Zhang, Liang Han, Mingming Tang, Bo You, Qicheng Zhang, Yiwen You
J. Cancer 2017; 8(18): 3887-3896. doi:10.7150/jca.19112
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Overexpression of α-sma-positive fibroblasts (CAFs) in Nasopharyngeal Carcinoma Predicts Poor Prognosis
Jiewei Chen, Pengfei Yang, Yongbo Xiao, Yijun Zhang, Jun Liu, Dan Xie, Muyan Cai, Xinke Zhang
J. Cancer 2017; 8(18): 3897-3902. doi:10.7150/jca.20324
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Effects of Triple Effective RNA (teRNA) on the Inhibition of Hepatocellular Carcinoma Cells
Yuwen Xue, Tiejun Li, Shuyan Liu, York Yuanyuan Zhu, Guilan Wang, Luyu Fu, Li Chen
J. Cancer 2017; 8(18): 3903-3915. doi:10.7150/jca.20958
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Pancreatic Cancer in Lynch Syndrome Patients
Luis Bujanda, Marta Herreros-Villanueva
J. Cancer 2017; 8(18): 3667-3674. doi:10.7150/jca.20750
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Strategies for Bispecific Single Chain Antibody in Cancer Immunotherapy
Shu-juan Zhou, Jia Wei, Shu Su, Fang-jun Chen, Yu-dong Qiu, Bao-rui Liu
J. Cancer 2017; 8(18): 3689-3696. doi:10.7150/jca.19501
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Roles of microRNAs in the resistance to platinum based chemotherapy in the non-small cell lung cancer
Hongjing Zang, Jianlun Peng, Weiyuan Wang, Songqing Fan
J. Cancer 2017; 8(18): 3856-3861. doi:10.7150/jca.21267
[Abstract] [Full text] [PDF] [PubMed] [PMC]