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Volume 7 (11); 2016

Research Paper

The Expression Levels of XLF and Mutant P53 Are Inversely Correlated in Head and Neck Cancer Cells
Sizhe Feng, Ramin Rabii, Guobiao Liang, Chenxi Song, Wei Chen, Mian Guo, Xuezhong Wei, Diana Messadi, Shen Hu
J. Cancer 2016; 7(11): 1374-1382. doi:10.7150/jca.14669
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Notch Signaling Activation in Cervical Cancer Cells Induces Cell Growth Arrest with the Involvement of the Nuclear Receptor NR4A2
Lichun Sun, Mingqiu Liu, Guang-Chun Sun, Xu Yang, Qingqing Qian, Shuyu Feng, L. Vienna Mackey, David H. Coy
J. Cancer 2016; 7(11): 1388-1395. doi:10.7150/jca.15274
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Complement Component 1, s Subcomponent Overexpression is an Independent Poor Prognostic Indicator in Patients with Urothelial Carcinomas of the Upper Urinary Tract and Urinary Bladder
I-Wei Chang, Victor Chia-Hsiang Lin, Wen-Jen Wu, Peir-In Liang, Wei-Ming Li, Bi-Wen Yeh, Hong-Lin He, Alex Chien-Hwa Liao, Ti-Chun Chan, Chien-Feng Li
J. Cancer 2016; 7(11): 1396-1405. doi:10.7150/jca.15339
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Exploration and Validation of C-Reactive Protein/Albumin Ratio as a Novel Inflammation-Based Prognostic Marker in Nasopharyngeal Carcinoma
Yuan Zhang, Guan-Qun Zhou, Xu Liu, Lei Chen, Wen-Fei Li, Ling-Long Tang, Qing Liu, Ying Sun, Jun Ma
J. Cancer 2016; 7(11): 1406-1412. doi:10.7150/jca.15401
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Degree of Lipiodol Accumulation Can Be an Indicator of Successful Treatment for Unresectable Hepatocellular Carcinoma (HCC) Patients - in the Case of Transcatheter Arterial Chemoembolization (TACE) and External Beam Radiotherapy (EBRT)
Ping Yang, Zhao-Chong Zeng, Bin-Liang Wang, Jian-Ying Zhang, Jia Fan, Jian Zhou, Yong Hu
J. Cancer 2016; 7(11): 1413-1420. doi:10.7150/jca.15405
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Centrosomal Protein of 55 Regulates Glucose Metabolism, Proliferation and Apoptosis of Glioma Cells via the Akt/mTOR Signaling Pathway
Guangzhi Wang, Mingna Liu, Hongjun Wang, Shan Yu, Zhenfeng Jiang, Jiahang Sun, Ke Han, Jia Shen, Minwei Zhu, Zhiguo Lin, Chuanlu Jiang, Mian Guo
J. Cancer 2016; 7(11): 1431-1440. doi:10.7150/jca.15497
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Proteomic Upregulation of Fatty Acid Synthase and Fatty Acid Binding Protein 5 and Identification of Cancer- and Race-Specific Pathway Associations in Human Prostate Cancer Tissues
Jennifer S. Myers, Ariana K. von Lersner, Qing-Xiang Amy Sang
J. Cancer 2016; 7(11): 1452-1464. doi:10.7150/jca.15860
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognostic Value of Neoadjuvant Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma with Low Pre-treatment Epstein-Barr Virus DNA: a Propensity-matched Analysis
Hao Peng, Lei Chen, Wen-Fei Li, Rui Guo, Yuan Zhang, Fan Zhang, Li-Zhi Liu, Li Tian, Ai-Hua Lin, Ying Sun, Jun Ma
J. Cancer 2016; 7(11): 1465-1471. doi:10.7150/jca.15736
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Point Mutation in DNA Polymerase β (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer
Xiaohui Tan, Xiaoling Wu, Shuyang Ren, Hongyi Wang, Zhongwu Li, Weaam Alshenawy, Wenmei Li, Jiantao Cui, Guangbin Luo, Robert S. Siegel, Sidney W. Fu, Youyong Lu
J. Cancer 2016; 7(11): 1472-1480. doi:10.7150/jca.14844
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Narrowing Resection of Parametrial Tissues Is Feasible in Low-Risk Cases of Stage IA2-IB1 Cervical Cancer
Xue-Lian Li, Xiao-Xia Liu, Guan-Shu Cao, Dan-Dan Ju, Hua Jiang
J. Cancer 2016; 7(11): 1481-1486. doi:10.7150/jca.15466
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Magnetofection Based on Superparamagnetic Iron Oxide Nanoparticles Weakens Glioma Stem Cell Proliferation and Invasion by Mediating High Expression of MicroRNA-374a
Zhiguang Pan, Zhifeng Shi, Hua Wei, Fengyan Sun, Jianping Song, Yongyi Huang, Te Liu, Ying Mao
J. Cancer 2016; 7(11): 1487-1496. doi:10.7150/jca.15515
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Cytotoxic Chemotherapy as First-Line Therapy for Advanced Non-Small-Cell Lung Cancer in Taiwan: Daily Practice
Yi-Hsin Liang, Yu-Yun Shao, Bin-Chi Liao, Ho-Sheng Lee, James Chih-Hsin Yang, Ho-Min Chen, Chun-Ju Chiang, Ann-Lii Cheng, Mei-Shu Lai
J. Cancer 2016; 7(11): 1515-1523. doi:10.7150/jca.15180
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma
Michihiro Kudou, Atsushi Shiozaki, Toshiyuki Kosuga, Daisuke Ichikawa, Hirotaka Konishi, Ryo Morimura, Shuhei Komatsu, Hisashi Ikoma, Hitoshi Fujiwara, Kazuma Okamoto, Shigekuni Hosogi, Takashi Nakahari, Yoshinori Marunaka, Eigo Otsuji
J. Cancer 2016; 7(11): 1524-1533. doi:10.7150/jca.15181
[Abstract] [Full text] [PDF] [PubMed] [PMC]

SOX4 Promotes Progression in OLP-Associated Squamous Cell Carcinoma
Yi Liu, Li Cui, Junwei Huang, Eoon Hye Ji, Wei Chen, Diana Messadi, Shen Hu
J. Cancer 2016; 7(11): 1534-1540. doi:10.7150/jca.15689
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognostic Impact of Thrombospodin-2 (THBS2) Overexpression on Patients with Urothelial Carcinomas of Upper Urinary Tracts and Bladders
I-Wei Chang, Chien-Feng Li, Victor Chia-Hsiang Lin, Hong-Lin He, Per-In Liang, Wen-Jeng Wu, Ching-Chia Li, Chun-Nung Huang
J. Cancer 2016; 7(11): 1541-1549. doi:10.7150/jca.15696
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Rho GTPase RhoJ is Associated with Gastric Cancer Progression and Metastasis
Chan Kim, Hannah Yang, Intae Park, Hong Jae Chon, Joo Hoon Kim, Woo Sun Kwon, Won Suk Lee, Tae Soo Kim, Sun Young Rha
J. Cancer 2016; 7(11): 1550-1556. doi:10.7150/jca.15578
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway
Kui-Jun Chen, Qing Li, Cang-mei Wen, Zhao-Xia Duan, Jie yuan Zhang, Chuan Xu, Jian-Min Wang
J. Cancer 2016; 7(11): 1557-1564. doi:10.7150/jca.15566
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Anti-ALK Antibodies in Patients with ALK-Positive Malignancies Not Expressing NPM-ALK
Christine Damm-Welk, Faraz Siddiqi, Matthias Fischer, Barbara Hero, Vignesh Narayanan, David Ross Camidge, Michael Harris, Amos Burke, Thomas Lehrnbecher, Karen Pulford, Ilske Oschlies, Reiner Siebert, Suzanne Turner, Wilhelm Woessmann
J. Cancer 2016; 7(11): 1383-1387. doi:10.7150/jca.15238
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon Cancer
Debolina Ray, Dawit Kidane
J. Cancer 2016; 7(11): 1421-1430. doi:10.7150/jca.15480
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Genomic/Epigenomic Alterations in Ovarian Carcinoma: Translational Insight into Clinical Practice
Anliang Dong, Yan Lu, Bingjian Lu
J. Cancer 2016; 7(11): 1441-1451. doi:10.7150/jca.15556
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Cancer of the Pancreas: Molecular Pathways and Current Advancement in Treatment
Kishore Polireddy, Qi Chen
J. Cancer 2016; 7(11): 1497-1514. doi:10.7150/jca.14922
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Hepatocellular Carcinoma and Diffusion-Weighted MRI: Detection and Evaluation of Treatment Response
Jill S Gluskin, Fabrizio Chegai, Serena Monti, Ettore Squillaci, Lorenzo Mannelli
J. Cancer 2016; 7(11): 1565-1570. doi:10.7150/jca.14582
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Effects of Animal Venoms and Toxins on Hallmarks of Cancer
Janeyuth Chaisakul, Wayne C. Hodgson, Sanjaya Kuruppu, Naiyarat Prasongsook
J. Cancer 2016; 7(11): 1571-1578. doi:10.7150/jca.15309
[Abstract] [Full text] [PDF] [PubMed] [PMC]