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Volume 8 (16); 2017

Research Paper

Hypothalamic beta-endorphin neurons suppress preneoplastic and neoplastic lesions development in 1,2-dimethylhydrazine induced rat colon cancer model
Sengottuvelan Murugan, Yatee Dave, Ankush Rakhit, Dipak. K. Sarkar
J. Cancer 2017; 8(16): 3105-3113. doi:10.7150/jca.18860
[Abstract] [Full text] [PDF]

A phase II trial of preoperative concurrent chemotherapy and dose escalated intensity modulated radiotherapy (IMRT) for locally advanced rectal cancer
Jeremy Tey, Cheng Nang Leong, Wai Kit Cheong, Tay Guan Sze, Wei Peng Yong, Ivan Weng Keong Tham, Khai Mun Lee
J. Cancer 2017; 8(16): 3114-3121. doi:10.7150/jca.21237
[Abstract] [Full text] [PDF]

Fascin expression is inversely correlated with breast cancer metastasis suppressor 1 and predicts a worse survival outcome in node-negative breast cancer patients
Hye Jin Lee, Hee Jung An, Tae Hoen Kim, Gwangil Kim, Haeyoun Kang, Jin Hyung Heo, Ah-Young Kwon, Sewha Kim
J. Cancer 2017; 8(16): 3122-3129. doi:10.7150/jca.22046
[Abstract] [Full text] [PDF]

FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway
Yanyan Chen, Xianping Rao, Kangmao Huang, Xiaoxia Jiang, Haohao Wang, Lisong Teng
J. Cancer 2017; 8(16): 3142-3153. doi:10.7150/jca.19273
[Abstract] [Full text] [PDF]

High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation
Chao-qin Shen, Ting-Ting Yan, Wei Liu, Xiao-qiang Zhu, Xiang-long Tian, Xue-liang Fu, Rong Hua, Jun-feng Zhang, Yan-miao Huo, De-jun Liu, Jian-yu Yang, Yong-Wei Sun, Jing-Yuan Fang, Hao-Yan Chen, Jie Hong
J. Cancer 2017; 8(16): 3154-3165. doi:10.7150/jca.20086
[Abstract] [Full text] [PDF]

Programmed Death Ligand 1 (PD-L1) Expression in Primary Angiosarcoma
Gerardo Botti, Giosuè Scognamiglio, Laura Marra, Antonio Pizzolorusso, Maurizio Di Bonito, Rossella De Cecio, Monica Cantile, Annarosaria De Chiara
J. Cancer 2017; 8(16): 3166-3172. doi:10.7150/jca.19060
[Abstract] [Full text] [PDF]

Arecoline Increases Glycolysis and Modulates pH Regulator Expression in HA22T/VGH Hepatoma Cells, Leading to Increase of Intracellular Ca2+, Reactive Oxygen Species, and Anoikis
Hsiao-Ling Cheng, Wen-Tsan Chang, Yu-Chen Hu, Bau-Shan Hsieh, Tzu-Ching Huang, Inn-Wen Chong, Li-Wen Huang, Kee-Lung Chang
J. Cancer 2017; 8(16): 3173-3182. doi:10.7150/jca.20523
[Abstract] [Full text] [PDF]

Synergy of purine-scaffold TLR7 agonist with doxorubicin on systemic inhibition of lymphoma in mouse model
Dong Gao, Wang Li, Wanmin Wang, Yongguang Cai, Yuhuan Wang, Xiaoling Luo, Chih-Chang Wei
J. Cancer 2017; 8(16): 3183-3189. doi:10.7150/jca.20015
[Abstract] [Full text] [PDF]

Correlation of cancer stem cell markers and immune cell markers in resected non-small cell lung cancer
Zhaoqin Huang, Haining Yu, Jianbo Zhang, Haiyan Jing, Wanqi Zhu, Xiaolin Li, Lingling Kong, Ligang Xing, Jinming Yu, Xiangjiao Meng
J. Cancer 2017; 8(16): 3190-3197. doi:10.7150/jca.20172
[Abstract] [Full text] [PDF]

Association between 8q24 Gene Polymorphisms and the Risk of Prostate Cancer: A Systematic Review and Meta-Analysis
Ran Li, Zhiqiang Qin, Jingyuan Tang, Peng Han, Qianwei Xing, Feng Wang, Shuhui Si, Xiaolu Wu, Min Tang, Wei Wang, Wei Zhang
J. Cancer 2017; 8(16): 3198-3211. doi:10.7150/jca.20456
[Abstract] [Full text] [PDF]

Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions
Yongzhi Yang, Peng Junjie, Cai Sanjun, Yanlei Ma
J. Cancer 2017; 8(16): 3212-3225. doi:10.7150/jca.19794
[Abstract] [Full text] [PDF]

Association between Sumoylation-Related Gene rs77447679 Polymorphism and Risk of Gastric Cancer (GC) in a Chinese Population
Ying Luo, Sihong You, Jirong Wang, Shuling Fan, Jie Shi, Ai Peng, Tingting Yu
J. Cancer 2017; 8(16): 3226-3231. doi:10.7150/jca.20587
[Abstract] [Full text] [PDF]

Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells
Peng Jin, De-zhi Wang, Chen-xi Lyu, Ya-ting Wang, Yu-qi He, Jian-qiu Sheng, Xuhang Li
J. Cancer 2017; 8(16): 3232-3241. doi:10.7150/jca.20833
[Abstract] [Full text] [PDF]

Radiotherapy Alone or Concurrent Chemoradiation for Esophageal Squamous Cell Carcinoma in Elderly Patients
Lina Zhao, Yongchun Zhou, Haitao Pan, Yutian Yin, Guangjin Chai, Yunfeng Mu, Feng Xiao, Steven H. Lin, Mei Shi
J. Cancer 2017; 8(16): 3242-3250. doi:10.7150/jca.20835
[Abstract] [Full text] [PDF]

PD-L1 is a Prognostic Biomarker in Resected NSCLC Patients with Moderate/high Smoking History and Elevated Serum SCCA Level
Lianjing Cao, Xinyue Wang, Shouying Li, Qiongjie Zhi, Yuqian Wang, Liuchun Wang, Kai Li, Richeng Jiang
J. Cancer 2017; 8(16): 3251-3260. doi:10.7150/jca.21118
[Abstract] [Full text] [PDF]

Improvement in prediction of prostate cancer prognosis with somatic mutational signatures
Shengping Zhang, Yafei Xu, Xinjie Hui, Fei Yang, Yueming Hu, Jianlin Shao, Hui Liang, Yejun Wang
J. Cancer 2017; 8(16): 3261-3267. doi:10.7150/jca.21261
[Abstract] [Full text] [PDF]

Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
Jianfeng Cui, Qiyu Bo, Ning Zhang, Shouzhen Chen, Meng Yu, Shiyu Wang, Jie Han, Pengxiang Chen, Dongqing Zhang, Yaofeng Zhu, Benkang Shi
J. Cancer 2017; 8(16): 3268-3273. doi:10.7150/jca.21555
[Abstract] [Full text] [PDF]

A Bottleneck in Understanding Metastatic Cancer Stem Cell of Peritoneal Seeding from Gastric Cancer: A Null Result in Brief
Xin-Zu Chen, Xiao-Hai Song, Xiao-Long Chen, Chang-Chun Li, Xian-Ming Mo, Jian-Kun Hu
J. Cancer 2017; 8(16): 3274-3277. doi:10.7150/jca.21669
[Abstract] [Full text] [PDF]

Gambogenic Acid Exerts Antitumor Activity in Hypoxic Multiple Myeloma Cells by Regulation of miR-21
Ping Liu, Xue Wu, Lu Dai, Zheng Ge, Chong Gao, Hongming Zhang, Fei Wang, Xiaoping Zhang, Baoan Chen
J. Cancer 2017; 8(16): 3278-3286. doi:10.7150/jca.19290
[Abstract] [Full text] [PDF]

Cytokine-Induced Killer Cells Modulates Resistance to Cisplatin in the A549/DDP Cell Line
Lili Yang, Chunjuan Du, Lei Wu, Jinpu Yu, Xiumei An, Wenwen Yu, Shui Cao, Hui Li, Xiubao Ren
J. Cancer 2017; 8(16): 3287-3295. doi:10.7150/jca.19426
[Abstract] [Full text] [PDF]

Association between Mismatch-repair Genetic variation and the Risk of Multiple Primary Cancers: A Meta-Analysis
Pengfei Kong, Ruiyan Wu, Yadong Lan, Wenzhuo He, Chenlu Yang, Chenxi Yin, Qiong Yang, Chang Jiang, Dazhi Xu, Liangping Xia
J. Cancer 2017; 8(16): 3296-3308. doi:10.7150/jca.19810
[Abstract] [Full text] [PDF]

Heparanase Contributes To Trans-Endothelial Migration of Hepatocellular Carcinoma Cells
Xiaopeng Chen, Wen Jiang, Chaofu Yue, Wenjun Zhang, Chaogang Tong, Dafei Dai, Bin Cheng, Chen Huang, Linming Lu
J. Cancer 2017; 8(16): 3309-3317. doi:10.7150/jca.20159
[Abstract] [Full text] [PDF]

Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53
Keli Chen, Fengjiao Zhang, Jie Ding, Yonghao Liang, Zetao Zhan, Yizhi Zhan, Long-hua Chen, Yi Ding
J. Cancer 2017; 8(16): 3318-3330. doi:10.7150/jca.20482
[Abstract] [Full text] [PDF]

Correlation of ALDH1 and Notch3 Expression: Clinical implication in Ovarian Carcinomas
Mi Joung Kim, A-Ram Kim, Ju-Yeon Jeong, Kwang-il Kim, Tae-Heon Kim, Chan Lee, Kwanghoe Chung, Young-Hyeh Ko, Hee-Jung An
J. Cancer 2017; 8(16): 3331-3342. doi:10.7150/jca.18955
[Abstract] [Full text] [PDF]

The Prognostic Value of Peripheral Benzodiazepine Receptor in Patients with Esophageal Squamous Cell Carcinoma
You-Fang Chen, Jing-Dun Xie, Yu-Chuan Jiang, Dong-Tai Chen, Jia-Hao Pan, Yong-Hua Chen, Yun-Fei Yuan, Zhe-Sheng Wen, Wei-An Zeng
J. Cancer 2017; 8(16): 3343-3355. doi:10.7150/jca.20739
[Abstract] [Full text] [PDF]

Distant Metastasis and Survival Outcomes after Computed Tomography-Guided Needle Biopsy in Resected Stage I-III Non-Small Cell Lung Cancer
Yuhui Xi, Jingli Fan, Dehai Che, Keke Zhai, Tingting Ren, Xiao Feng, Lihua Shang, Jing Hu, Yan Yu, Qingwei Meng
J. Cancer 2017; 8(16): 3356-3361. doi:10.7150/jca.20784
[Abstract] [Full text] [PDF]

Alkaline Phosphatase-To-Albumin Ratio as a Prognostic Indicator in Pancreatic Ductal Adenocarcinoma after Curative Resection
Ning Pu, Shanshan Gao, Yadong Xu, Guochao Zhao, Yang Lv, Abulimiti Nuerxiati, Jian-ang Li, Dansong Wang, Xuefeng Xu, Tiantao Kuang, Xiaolin Wang, Wenhui Lou, Lingxiao Liu, Wenchuan Wu
J. Cancer 2017; 8(16): 3362-3370. doi:10.7150/jca.20917
[Abstract] [Full text] [PDF]

Phosphorylated Protein Kinase C (Zeta/Lambda) Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Characteristics and Prognosis
Min-kyung Yeo, Ji Yeon Kim, In-ock Seong, Jin-Man Kim, Kyung-Hee Kim
J. Cancer 2017; 8(16): 3371-3377. doi:10.7150/jca.20983
[Abstract] [Full text] [PDF]

Review

Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping
Xiaofeng Dai, Hongye Cheng, Zhonghu Bai, Jia Li
J. Cancer 2017; 8(16): 3131-3141. doi:10.7150/jca.18457
[Abstract] [Full text] [PDF]

Erratum

Retraction: The Epstein-Barr Virus-encoded miR-BART22 targets MAP3K5 to promote host cell proliferative and invasive abilities in nasopharyngeal carcinoma
Ruichao Chen, Minfeng Zhang, Qiulian Li, Hanzhen Xiong, Shaoyan Liu, Weiyi Fang, Qianbing Zhang, Zhen Liu, Xuehu Xu, Qingping Jiang
J. Cancer 2017; 8(16): 3130. doi:10.7150/jca.22507
[Abstract] [Full text] [PDF]