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Research Paper Selective sensitivity of betel nut-related oral squamous cell carcinoma to evodiamine through cell cycle arrest, growth inhibition and apoptosis induction Full text PDF
Research Paper Comprehensive Characterization and Prognostic Modeling of Efferocytosis-Related Genes in Cutaneous Melanoma Full text PDF
Research Paper GPCRs interaction with LGR5: Implications to cancer stemness Full text PDF
Research Paper Arteannuin B Induces Ferroptosis in Colorectal Cancer Cells via GDF15/HMGCS1/GPX4 Axis Full text PDF PubMed PMC
Review tsRNA's Biological Function and its Potential Application in Disease Diagnosis and Prognosis Full text PDF PubMed PMC
Research Paper Long-Term Empagliflozin Treatment (50 Days) Attenuates Protease Activity, Migration, and Stemness-Associated Phenotypes in BFTC-909 Renal Pelvis Transitional Cell Carcinoma Cells Full text PDF PubMed PMC
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Head and neck cancer, particularly oral squamous cell carcinoma (OSCC), remains a major global health burden, with especially high incidence and mortality in Taiwan due to the widespread habit of betel quid chewing. Betel nut mediated OSCC (BN-OSCC) is characterized by aggressive clinical behavior, including increased risks of recurrence, metastasis, and poor survival outcomes, and exhibits limited responsiveness to conventional chemoradiotherapy. ...
Arteannuin B Induces Ferroptosis in Colorectal Cancer Cells via GDF15/HMGCS1/GPX4 Axis
Purpose: Drug resistance in colorectal cancer (CRC) necessitates novel therapeutic strategies. This study investigated whether arteannuin B, a sesquiterpene lactone from Artemisia annua, induces ferroptosis in CRC cells and elucidated the underlying molecular mechanism. Methods: Anti-CRC effects were assessed via MTT assays and xenograft models. Proteomics identified differentially expressed proteins. Arteannuin B-induced ferroptosis was confirmed ...