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Research Paper Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis Full text PDF
Research Paper PKM2 is the Metabolic Checkpoint for Stemness Features in Head and Neck Cancer Full text PDF
Review Field cancerization in urothelial carcinoma: molecular alterations and clinical implications Full text PDF
Research Paper Mitochondrial Parameters influence Chemosensitivity in Gastric Cancer Cells Full text PDF
Review Environmental co-exposure to microplastics and phenol may influence redox signaling and tumor microenvironment dynamics Full text PDF
Research Paper Potential influence of long non-coding RNA NEAT1 genetic variants and expression levels on the progression of prostate cancer Full text PDF
Issue 8; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
PKM2 is the Metabolic Checkpoint for Stemness Features in Head and Neck Cancer
Owing to their self-renewal, differentiation capabilities, and increased chemoresistance, cancer stem cells (CSCs) are associated with poor prognosis and an elevated chance of relapse and metastasis. CSCs survive under therapy-imposed pressure and aggravate tumor malignancy through metabolic reprogramming, leading to treatment failure. The RNA level of pyruvate kinase isoenzyme M2 (PKM2) is increased in head and neck cancer (HNC) tissues and is linked ...
Environmental exposure patterns have shifted from single-compound exposure to complex co-exposure scenarios. Among widespread pollutants, microplastics (MPs) and phenol may interact biologically despite their distinct physicochemical properties. Phenol is associated with oxidative stress-related toxicity, whereas MPs may serve as potential carriers and redox-active modifiers. This review proposes that MP-induced oxidative stress and phenol-mediated ...