Impact Factor ISSN: 1837-9664
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Research Paper
Longitudinal CT-based deep learning radiomics for predicting prognosis in esophageal squamous cell carcinoma treated with definitive chemoradiotherapy: a two-center study
Xinyang Hu, Wubulaishan Maitudi, Xi Chen, Lina Zhao, Qingsong Pang
J. Cancer 2026; 17(4): 808-818. doi:10.7150/jca.126804
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Research Paper
Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer
Bing Ang, Yi Bai, Xiyue Deng, Qiong Wu, Yuqian Wang, Shanshan Xu, Weixin Zhang, Yang Li, Dapeng Chen, Ruixi Li, Siyang Li, Zhigang Zhao, Yamin Zhang
J. Cancer 2026; 17(4): 797-807. doi:10.7150/jca.127225
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Research Paper
WISP-3 promotes angiogenesis in non-small cell lung cancer through p38/JNK-c-Jun-mediated PDGF-A upregulation
En-Ming Chang, Syuan-Ling Lin, Ching-Yuan Cheng, Chih-Hsin Tang, Yu-Chen Chen, Chiang-Wen Lee, Chih-Yang Lin
J. Cancer 2026; 17(4): 787-796. doi:10.7150/jca.127681
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Research Paper
High PMS2 Expression-Based Nomogram for Risk Stratification in Resected Hepatocellular Carcinoma: Application to Recurrence and Neoadjuvant Therapy Selection
Wenchen Gong, Ruyu Han, Liyu Sun, Yingrui Gao, Zhiqiang Han, Yimeng Wang, Yuren Xia, Yukun Wei, Tianqiang Song, Lu Chen, Xiangdong Tian
J. Cancer 2026; 17(4): 771-786. doi:10.7150/jca.131997
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Review
Roles of Cellular Neighborhoods in Lung Cancer
Rui Bai, Wenjie Sun
J. Cancer 2026; 17(4): 759-770. doi:10.7150/jca.132848
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Research Paper
An integrated bulk and single-cell transcriptomic analysis reveals stemness-driven immune regulation and therapeutic vulnerability in colorectal cancer
I-Hung Chen, Kai-Fu Chang, Chien-Cheng Chao, Chung-Hsien Lin, Chih-Hsuan Chang, Ching-Chung Ko, Hui-Ru Lin, Chi-Jen Wu, Chien-Han Yuan, Sachin Kumar, Dahlak Daniel Solomon, Do Thi Minh Xuan, Neethu Palekkode, Ayman Fathima, Yung-Kuo Lee, Chung-Bao Hsieh, Yuen-Jung Wu
J. Cancer 2026; 17(4): 740-758. doi:10.7150/jca.132694
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Issue 3; 2026
Indexed in PubMed and SCI expanded; full texts in PubMed Central and Europe PMC. ...
Purpose: To develop and validate a longitudinal deep-learning based survival prediction model for esophageal squamous cell carcinoma (ESCC) patients who received definitive concurrent chemoradiotherapy (CCRT). Methods: A total of 257 ESCC patients from two centers were recruited. Among them, 205 patients were in the training cohort and 52 in the external testing cohort. The CrossFormer algorithm was utilized to extract features from pre- and post- ...
Roles of Cellular Neighborhoods in Lung Cancer
The occurrence and development of lung cancer (LC) involve complex interactions between various cell types in the tumor microenvironment (TME). Understanding the spatial distribution and interaction mechanisms of these cells may be the key to overcoming LC. The advancements of single-cell and spatial transcriptome techniques have promoted our understanding of cellular neighborhoods (CNs) and their functions in the pathogenesis of LC. In this review, ...