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Research Paper Selective sensitivity of betel nut-related oral squamous cell carcinoma to evodiamine through cell cycle arrest, growth inhibition and apoptosis induction Yin-Che Lu, Kai-Liang Tang, Chih-Hsien Liao, Yi-Zhen Li, Chin-Ho Kuo, Pin-Tzu Chen, Shu-Hsin Chen, Ying-Ray Lee J. Cancer 2026; 17(8): 1435-1444. doi:10.7150/jca.136981 Full text PDF


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Research Paper Comprehensive Characterization and Prognostic Modeling of Efferocytosis-Related Genes in Cutaneous Melanoma Yuliang Sun, Zhihu Ma, Yanlin Li, Anhao Shi, Gang Wang J. Cancer 2026; 17(8): 1419-1434. doi:10.7150/jca.130446 Full text PDF


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Research Paper GPCRs interaction with LGR5: Implications to cancer stemness Jeetendra K Nag, Ganesh Subedi, Tatyana Rudina, Rachel Bar-Shavit J. Cancer 2026; 17(8): 1408-1418. doi:10.7150/jca.134767 Full text PDF


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Research Paper Arteannuin B Induces Ferroptosis in Colorectal Cancer Cells via GDF15/HMGCS1/GPX4 Axis Xiaozheng Ou, Jinghong Xu, Yuting Jin, Yanqing Wang, Rongmin Yu, Jianhua Zhu, Weijuan Huang, Liyan Song J. Cancer 2026; 17(7): 1393-1407. doi:10.7150/jca.128611 Full text PDF PubMed PMC


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Review tsRNA's Biological Function and its Potential Application in Disease Diagnosis and Prognosis Congcong Tang, Qi Tang, Siyuan Tang, Faqing Tang J. Cancer 2026; 17(7): 1384-1392. doi:10.7150/jca.135857 Full text PDF PubMed PMC


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Research Paper Long-Term Empagliflozin Treatment (50 Days) Attenuates Protease Activity, Migration, and Stemness-Associated Phenotypes in BFTC-909 Renal Pelvis Transitional Cell Carcinoma Cells Yi-Hsun Lee, Pei-Ni Chen, Yi-Hsien Hsieh, Yi-Cheng Chu, Li-Jeng Chen, Chin-Yin Lin, Shun-Fa Yang, Horng-Rong Chang J. Cancer 2026; 17(7): 1373-1383. doi:10.7150/jca.132959 Full text PDF PubMed PMC

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Long-Term Empagliflozin Treatment (50 Days) Attenuates Protease Activity, Migration, and Stemness-Associated Phenotypes in BFTC-909 Renal Pelvis Transitional Cell Carcinoma Cells

Empagliflozin is a sodium-glucose cotransporter 2 inhibitor widely prescribed for the treatment of type 2 diabetes mellitus. It promotes urinary glucose excretion by inhibiting renal glucose reabsorption. Although empagliflozin has been widely used in clinical practice, its effects and underlying mechanisms related to metastasis, cytokine secretion, and stemness-associated phenotypes in renal pelvis transitional cell carcinoma (TCC) remain poorly ...


tsRNA's Biological Function and its Potential Application in Disease Diagnosis and Prognosis

Under physiological conditions, tsRNAs regulate mRNA transcription, reverse transcription, and protein translation to mediate cell apoptosis, cell cycle, and epigenetic regulation. Pathogenic tsRNAs are disease-specific or disease-related tsRNAs that are highly express in various diseases and may serve as diagnostic or potential diagnostic biomarkers. Specifically expressed tsRNAs in tumors were screened and obtained from the tumors. Although the ...

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