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Research Paper Single-Cell-Derived Malignant Epithelial Programs Define Prognostic Risk and Therapeutic Vulnerability in Ovarian Cancer Full text PDF
Research Paper Association of DNA damage response gene polymorphisms with treatment response and prognosis in acute myeloid leukemia Full text PDF
Research Paper Microfluidic Immunomagnetic Capture of Circulating Tumor Cells via On-Bead Antibody Conjugation Full text PDF
Research Paper Association of NAP1L1 polymorphism with clinicopathological progression in oral squamous cell carcinoma Full text PDF
Review Emerging Oncolytic Viruses: Beyond Adenoviruses and Herpes Simplex Virus Full text PDF PubMed PMC
Research Paper GALNT14-rs9679162 Genotypes Predict Post-immunotherapy Side Effect and Survival in Patients with Hepatitis B Virus-related Hepatocellular Carcinoma Full text PDF PubMed PMC
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
The potential functional Single Nucleotide Polymorphism (SNPs) of DNA Damage Response (DDR)-related genes may influence AML aggressiveness and clinical outcomes through regulating genomic stability. However, systematic evaluation of functionally relevant SNPs across the entire DDR cascade in AML remains limited. In our study, significant associations were identified across multiple DDR modules. In the damage sensing module, MRE11 rs2155209 TC/CC genotypes ...
Background: Ovarian cancer (OV) is characterized by pronounced intratumoral heterogeneity and unfavorable clinical outcomes, yet clinically applicable biomarkers for risk stratification remain limited. Although bulk transcriptomic models have been widely proposed, they often overlook the cellular origins of prognostic signals. Advances in single-cell RNA sequencing (scRNA-seq) provide an opportunity to resolve malignant epithelial diversity and identify ...