Review Anticancer Effects of Cepharanthine: an Updated Minireview Full text PDF
Research Paper A squamous epithelial gene interaction perturbation network index for risk stratification in esophageal squamous cell carcinoma Full text PDF
Review The Role of Lipid Metabolism in the Progression of Breast Cancer Full text PDF
Research Paper Association between Oxidative Balance Score and Colorectal Cancer: Insights from NHANES 1999-2018 Full text PDF
Research Paper Circulating Tumor Cells Detected Using EpAb3-5 as Prognostic Indicators in Head and Neck Squamous Cell Carcinoma Full text PDF
Review Myeloid-Derived Suppressor Cells and Radiotherapy: Regulation and Clinical Implications Full text PDF
Issue 3; 2026
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Anticancer Effects of Cepharanthine: an Updated Minireview
Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid, has a long history of clinical use in Japan for various diseases. Over the past few decades, it is potent anticancer activities have garnered significant attention. In this review shows CEP exhibits anti-cancer activity via diverse mechanisms: it induces programmed cell death via intrinsic mitochondrial pathways, extrinsic death receptor signaling, and endoplasmic reticulum stress. It also arrests ...
Background: EpAb3-5, an anti-EpCAM (epithelial cell adhesion molecule) neutralizing antibody, enhances circulating tumor cell (CTC) detection, but its clinical and prognostic relevance in head and neck squamous cell carcinoma (HNSCC) remains unclear. Methods: We retrospectively analyzed 66 HNSCC patients. CTCs were enumerated using EpAb3-5 and a commercial EpCAM-based platform (MACS), and tumor EpCAM expression detected using EpAb3-5 was assessed ...