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Research Paper Targeting MUC16 to Reverse Anoikis Resistance: A Promising Strategy for Metastatic Lung Adenocarcinoma Therapy Kulsoom, Wajahat Ali, Zhe Ma, Wen Cai, Zhenlong Wang, Fu Wang J. Cancer 2026; 17(4): 819-834. doi:10.7150/jca.131494 Full text PDF


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Research Paper Longitudinal CT-based deep learning radiomics for predicting prognosis in esophageal squamous cell carcinoma treated with definitive chemoradiotherapy: a two-center study Xinyang Hu, Wubulaishan Maitudi, Xi Chen, Lina Zhao, Qingsong Pang J. Cancer 2026; 17(4): 808-818. doi:10.7150/jca.126804 Full text PDF


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Research Paper Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer Bing Ang, Yi Bai, Xiyue Deng, Qiong Wu, Yuqian Wang, Shanshan Xu, Weixin Zhang, Yang Li, Dapeng Chen, Ruixi Li, Siyang Li, Zhigang Zhao, Yamin Zhang J. Cancer 2026; 17(4): 797-807. doi:10.7150/jca.127225 Full text PDF


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Research Paper WISP-3 promotes angiogenesis in non-small cell lung cancer through p38/JNK-c-Jun-mediated PDGF-A upregulation En-Ming Chang, Syuan-Ling Lin, Ching-Yuan Cheng, Chih-Hsin Tang, Yu-Chen Chen, Chiang-Wen Lee, Chih-Yang Lin J. Cancer 2026; 17(4): 787-796. doi:10.7150/jca.127681 Full text PDF


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Research Paper High PMS2 Expression-Based Nomogram for Risk Stratification in Resected Hepatocellular Carcinoma: Application to Recurrence and Neoadjuvant Therapy Selection Wenchen Gong, Ruyu Han, Liyu Sun, Yingrui Gao, Zhiqiang Han, Yimeng Wang, Yuren Xia, Yukun Wei, Tianqiang Song, Lu Chen, Xiangdong Tian J. Cancer 2026; 17(4): 771-786. doi:10.7150/jca.131997 Full text PDF


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Review Roles of Cellular Neighborhoods in Lung Cancer Rui Bai, Wenjie Sun J. Cancer 2026; 17(4): 759-770. doi:10.7150/jca.132848 Full text PDF

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Issue 3; 2026

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Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...


Longitudinal CT-based deep learning radiomics for predicting prognosis in esophageal squamous cell carcinoma treated with definitive chemoradiotherapy: a two-center study

Purpose: To develop and validate a longitudinal deep-learning based survival prediction model for esophageal squamous cell carcinoma (ESCC) patients who received definitive concurrent chemoradiotherapy (CCRT). Methods: A total of 257 ESCC patients from two centers were recruited. Among them, 205 patients were in the training cohort and 52 in the external testing cohort. The CrossFormer algorithm was utilized to extract features from pre- and post- ...


Targeting MUC16 to Reverse Anoikis Resistance: A Promising Strategy for Metastatic Lung Adenocarcinoma Therapy

Background: Although the mucin glycoprotein MUC16 is well established as an oncogenic biomarker in ovarian cancer, its mechanistic contribution to lung adenocarcinoma (LUAD) remains poorly defined. This study integrates multi-omics profiling and functional validation to uncover MUC16 as a novel determinant of detachment-induced survival in LUAD. Methods: Transcriptomic and clinical data from TCGA-LUAD and GEO cohorts were analyzed to identify differentially ...

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