Impact Factor ISSN: 1837-9664
Research Paper Bevacizumab or Aflibercept in Combination with Second-Line FOLFIRI after Progression on FOLFOX Plus Bevacizumab in Metastatic Colorectal Cancer: A Comparative Study Full text PDF
Review Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer Full text PDF
Research Paper Associations of HMGA2 single-nucleotide polymorphisms with clinicopathological features of tongue squamous cell carcinoma in Taiwanese men with distinct lifestyle-related risk factors Full text PDF
Research Paper Separability of histopathology foundation model embeddings of stimulated Raman histology images for lung carcinoma subtyping Full text PDF
Review Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges Full text PDF
Review Regulatory roles of E3 ubiquitin ligase RNF128 in inflammatory diseases and tumors Full text PDF
Issue 9; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Background: Oral squamous cell carcinoma (OSCC) is a predominant malignancy of the oral cavity, with tongue squamous cell carcinoma (TSCC) accounting for a substantial proportion of cases worldwide. High-mobility group A protein 2 (HMGA2) is a nonhistone chromatin-binding factor implicated in aggressive malignant phenotypes of various human cancers. However, the effects of HMGA2 variants on OSCC susceptibility and tumor clinicopathological aggressiveness ...
Chimeric Antigen Receptor T cells (CAR-T) therapy represents a groundbreaking technology in the field of tumor immunotherapy. This innovative approach involves the genetic engineering of T cells to specifically identify and eradicate tumor cells, and it has been shown to yield remarkable efficacy in treating hematological malignancies. This article provides a comprehensive overview of the core advancements in CAR-T technology, emphasizing the evolution ...