Online advance articles

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Nomogram Models for Predicting Risk and Prognosis of Newly Diagnosed Ovarian Cancer Patients with Liver Metastases-- A Large Population-Based Real-World Study
Gui-Min Hou,Chuang Jiang,Jin-peng Du,Chang Liu,Xiang-zheng Chen,Ke-fei Yuan,Hong Wu,and Yong Zeng
J. Cancer 2021; doi:10.7150/jca.64255; in press
[Author manuscript]

Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1
Juan Wang, Xiaolan Cai, Liqiang Zhang, Dapeng Lei
J. Cancer 2021; doi:10.7150/jca.62112; accepted
[Author manuscript]

High-performance collective biomarker from liquid biopsy for diagnosis of pancreatic cancer based on mass spectrometry and machine learning
Tomohiko Iwano, Kentaro Yoshimura, Genki Watanabe, Ryo Saito, Sho Kiritani, Hiromichi Kawaida, Takeshi Moriguchi, Tasuku Murata, Koretsugu Ogata, Daisuke Ichikawa, Junichi Arita, Kiyoshi Hasegawa, Sen Takeda
J. Cancer 2021; doi:10.7150/jca.63244; accepted
[Author manuscript]

Unique cohorts of salivary gland cancer cells as an in-vitro model of circulating tumor cells
Callie Mincy, Donald Reed, Kathryn Carter, Luke Revelt, Anita Joy
J. Cancer 2021; doi:10.7150/jca.62570; accepted
[Author manuscript]

A Prospective Cohort Study of Biomarkers in Squamous Cell Carcinoma of the Anal Canal (SCCAC) and Their Influence on Treatment Outcomes
Camila Motta Venchiarutti Moniz, Rachel Pimenta Riechelmann, Suilane Coelho Ribeiro Oliveira, Giovanni Mendonça Bariani, Thomas Giollo Rivelli, Cintia Ortega, Allan Andresson Lima Pereira, Sibele Inácio Meireles, Rejane Franco, Andre Chen, Renata Colombo Bonadio, Caio Nahas, Jorge Sabbaga, Renata Almeida Coudry, Maria Ignez Braghiroli, Paulo Marcelo Hoff
J. Cancer 2021; doi:10.7150/jca.57678; in press
[Author manuscript]

B7-H3 inhibits apoptosis of gastric cancer cell by interacting with Fibronectin
Meiyun Sun, Jinjing Xie, Dongze Zhang, Chunyang Chen, Simin Lin, Yan Chen, Guangbo Zhang
J. Cancer 2021; doi:10.7150/jca.59263; accepted
[Author manuscript]

Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer
Shuchang Ren, Xiaohui Tan, Melinda Z. Fu, Shuyang Ren, Xiaoling Wu, Tao Chen, Patricia S. Latham, Paul Lin, Yan-gao Man and Sidney W. Fu
J. Cancer 2021; doi:10.7150/jca.63836; in press
[Author manuscript]

High Expression of ERK-related RASGRF2 Predicts Poor prognosis in Patients with Stomach Adenocarcinoma and Correlates with defective immune infiltration
Yaqi Du, Zhengguang Wang, Weina Wan
J. Cancer 2021; doi:10.7150/jca.63029; in press
[Author manuscript]

MiR-182-5p Promotes the Metastasis and Epithelial-mesenchymal Transition in Non-small Cell Lung Cancer by Targeting EPAS1
Wenxiao Yang, Yinan Yin, Ling Bi, Yichao Wang, Jialin Yao, Ling Xu and Lijing Jiao
J. Cancer 2021; doi:10.7150/jca.60419; in press
[Author manuscript]

CPNE3 regulates the cell proliferation and apoptosis in human GBM via the activation of PI3K/AKT signaling pathway
Dainan Zhang, Xiaoyin Wang, Xi Wang, Zemin Wang, Shunchang Ma, Chuanbao Zhang, Shaomin Li and Wang Jia
J. Cancer 2021; doi:10.7150/jca.60049; accepted
[Author manuscript]

CircRNA_400029 promotes the aggressive behaviors of cervical cancer by regulation of miR-1285-3p/TLN1 axis
Yue Ma, Jing Liu, Zhuo Yang, Peng Chen, Dan-bo Wang
J. Cancer 2021; doi:10.7150/jca.61437; accepted
[Author manuscript]

Effectiveness and safety of Chinese herbal injections combined with fluoropyrimidine and oxaliplatin-based chemotherapy for advanced colorectal cancer: a systematic review and meta-analysis of 63 randomized controlled trials
Shuo Wang, Xueqian Wang, Tong Zhou, Shuaihang Hu, Peiyu Tian,Zheng Li,Yuxiao Li,Jun Dong,Yuerong Gui, Dandan Wang, Ying Zhang, Wei Hou
J. Cancer 2021; doi:10.7150/jca.60895; in press
[Author manuscript]

Mutational Characterization of Colorectal Cancer from Korean Patients with Targeted Sequencing
Jongmin Lee, Sangtae Choi, Donghae Jung, YunJae Jung, Jung Ho Kim, Sungwon Jung, Won-Suk Lee
J. Cancer 2021; doi:10.7150/jca.61324; accepted
[Author manuscript]

OTUD7A Suppresses Lung Cancer Progression via Regulating Cell Proliferation and Apoptosis
Han Chen, Jie Gao, Dandong Dai, Jiaqi Ji, Tongde Du, Yongsheng Yu, Qian Zhou, and Yongqi Shan
J. Cancer 2021; doi:10.7150/jca.62482; in press
[Author manuscript]

β-arrestin2 regulating β2-adrenergic receptor signaling in hepatic stellate cells contributes to hepatocellular carcinoma progression
Xiu-Qin Li, Wen-Ting Peng, Shan Shan, Jing-Jing Wu, Nan Li, Jia-Jia Du, Jia-Chang Sun, Ting-Ting Chen, Wei Wei, Wu-Yi Sun
J. Cancer 2021; doi:10.7150/jca.59291; accepted
[Author manuscript]

Clinicalpathologic and Prognostic Significance of CGI-58 in Endometrial Cancer
Zhengzheng Shi, Xishao Luo, Hongqin Zhao, Baoyou Huang, Yuanqiu Wang, Xu Chen, Jiangtao Yu
J. Cancer 2021; doi:10.7150/jca.61905; accepted
[Author manuscript]

The association between pretreatment anemia and overall survival in advanced non-small cell lung cancer: A retrospective cohort study using propensity score matching
Yucong Huang, Cuiyun Su, Huiqin Jiang, Feiwen Liu, Qitao Yu, Shaozhang Zhou
J. Cancer 2021; doi:10.7150/jca.55159; accepted
[Author manuscript]

Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway
Zhiyong Li, Yunning Huang, Yuanyi Xu, Xiaofei Wang, Honghong Wang, Shuai Zhao, Han Liu, Guangfu Yu, Xiangming Che
J. Cancer 2021; doi:10.7150/jca.61031; accepted
[Author manuscript]

Anticancer Effects of Helminthostachys zeylanica Ethyl acetate Extracts on Human Gastric Cancer Cells Through Downregulation of the TNF-alpha-Activated COX-2–cPLA2–PGE2 Pathway
Ming-Ming Tsai, Horng-Chyuan Lin, Ming-Chin Yu, Wan-Jung Lin, Mei-Yi Chu, Ching-Ching Tsai and Ching-Yi Cheng
J. Cancer 2021; doi:10.7150/jca.64638; in press
[Author manuscript]

ZNF750 exerted its antitumor action in oral squamous cell carcinoma by regulating E2F2
Hong-Li Yang, Cong Xu, Yi-Kun Yang, Wen-Qiang Tang, Min Hong, Li Pan, Hai-Ying Chen
J. Cancer 2021; doi:10.7150/jca.63919; in press
[Author manuscript]

Elevated expression of Tweety homologue 3 predicts poor clinical outcomes in ovarian cancer
Junhan Zhou, Yichi Xu, Xin Chen, Fengyun Chen, Jianan Zhang, Xueqiong Zhu
J. Cancer 2021; doi:10.7150/jca.63539; in press
[Author manuscript]

RBM47 downregulation promotes renal cancer cell malignancy and predicts poor patient survival
Cheng Wang, Xiangui Meng, Zhiyong Xiong, Yuzhong Ye, Changfei Yuan, Jian Shi, Zhixian Chen, Di Liu, Wen Xiao, Xiaoping Zhang
J. Cancer 2021; doi:10.7150/jca.56425; accepted
[Author manuscript]

PTPRO is a therapeutic target and correlated with immune infiltrates in pancreatic cancer
Xuben Hou, Jintong Du and Hao Fang
J. Cancer 2021; doi:10.7150/jca.64661; accepted
[Author manuscript]

LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer
Zhengchao Shen, Yingying Pan, Peng Chen, Bin Jiang, Xiaosan Fang and Yaqi Jiang
J. Cancer 2021; doi:10.7150/jca.62211; accepted
[Author manuscript]

N6-methyladenosine regulates ATM expression and downstream signaling
Xiaoyue Zhang, Peishan Liu, Xiang Zheng, Jia Wang, Qiu Peng, Zhengshuo Li, Lingyu Wei, Can Liu, Yangge Wu, Yuqing Wen, Qun Yan, Jian Ma
J. Cancer 2021; doi:10.7150/jca.64061; in press
[Author manuscript]

Decipher the Helicobacter pylori Protein Targeting in the Nucleus of Host Cell and their Implications in Gallbladder Cancer: An Insilico Approach
Yunjian Wang Shahanavaj Khan, Ahamad Imran, Anis Ahmad Chaudhary
J. Cancer 2021; doi:10.7150/jca.63517; in press
[Author manuscript]

Epithelial-to-Mesenchymal Transition in Pancreatic Cancer is associated with Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging
Philipp Mayer, Anne Kraft, Wilfried Roth, Thilo Hackert, Frank Bergmann, Hans-Ulrich Kauczor, Verena Steinle, Ekaterina Khristenko, Miriam Klauss, Matthias M. Gaida
J. Cancer 2021; doi:10.7150/jca.63633; accepted
[Author manuscript]

PD-L1 Expression in Chinese Patients with Advanced Non-Small Cell Lung Cancer (NSCLC): A Multi-Center Retrospective Observational Study
Xin Yang, Lili Jiang, Yan Jin, Peng Li, Yingyong Hou, Jingping Yun, Chunyan Wu, Wenyong Sun, Xiangshan Fan, Dong Kuang, Weiya Wang, Jinsong Ni, Anhua Mao, Wenmin Tang, Zhenhua Liu, Jiali Wang, Suijun Xiao, Yuan Li, Dongmei Lin
J. Cancer 2021; doi:10.7150/jca.63003; accepted
[Author manuscript]

The role of long non-coding RNA linc01296 in oral squamous cell carcinoma: a study based on bioinformatics analysis and in vitro validation
Kaicheng Yang, Lei Li, Yanping Chen, Shasha Man, Lei Yang, Yinglai Yang, Naiheng Hei, Jianguang Zhao
J. Cancer 2021; doi:10.7150/jca.60417; accepted
[Author manuscript]

Immunohistochemical Detection of Human Papillomavirus 16 E7 Oncoprotein in Cervical Lesions
Jiang Zhu, Lingjing Chen, Qiaoli Zheng, Rui Han, Xianzhen Chen, Qiang Zhou, Hao Cheng
J. Cancer 2021; doi:10.7150/jca.60554; in press
[Author manuscript]

Comprehensive bioinformatics analyses of APOBECs family and identification of APOBEC3D as the unfavorable prognostic biomarker in clear cell renal cell carcinoma
Zhenpeng Zhu, Xing Ji, Weijie Zhu, Tianyu Cai, Chunru Xu, Cong Huang, Shiming He, Yanqing Gong, Xuesong Li, Jian Lin, Liqun Zhou
J. Cancer 2021; doi:10.7150/jca.61972; in press
[Author manuscript]

Predicting early refractoriness of transarterial chemoembolization in patients with hepatocellular carcinoma using a random forest algorithm: a pilot study
Zhi-Min Zou, Tian-Zhi An, Jun-Xiang Li, Zi-Shu Zhang, Yu-Dong Xiao, Jun Liu
J. Cancer 2021; doi:10.7150/jca.63370; in press
[Author manuscript]

uPAR: An Essential Factor for Tumor Development
Tao Lv, Ying Zhao, Xinni Jiang, Hemei Yuan, Haibo Wang, Xuelin Cui, Jiashun Xu, Jingye Zhao, Lizhou Tang, Jianlin Wang
J. Cancer 2021; doi:10.7150/jca.62281; in press
[Author manuscript]

Diagnostic Performance of Diffusion MRI for Differentiating Benign and Malignant Nonfatty Musculoskeletal Soft Tissue Tumors: A Systematic Review and Meta-analysis
Qian Wang, Xinguang Xiao, Yanchang Liang, Hao Wen, Xiaopeng Wen, Meilan Gu, Cuiping Ren, Kunbin Li, Liangwen Yu, Liming Lu
J. Cancer 2021; doi:10.7150/jca.62131; accepted
[Author manuscript]

Downregulation of LOX promotes castration-resistant prostate cancer progression via IGFBP3
Xuanrong Chen, Yi Shao, Wanqing Wei, Haishan Shen, Yang Li, Yutong Chen, Qianwang Ma, Hanlin Li, Zhao Yang, Yuanjie Niu, Zhiqun Shang
J. Cancer 2021; doi:10.7150/jca.61131; accepted
[Author manuscript]

Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway
Jing Zhang, Pengfei Li, Ting Li, Zhiqin Zhou, Huiling Wu, Lei Zhang
J. Cancer 2021; doi:10.7150/jca.62873; accepted
[Author manuscript]

LncRNA XIST promotes the proliferation of colorectal cancer cells by upregulating the expression of the miR-92b-3p target gene NLK
Xinyan Chen, Yifan Zhou, Yufeng Wan, Tingting Chen, Huaqing Zhu, Xiaowen Cheng
J. Cancer 2021; doi:10.7150/jca.62526; in press
[Author manuscript]

Clinical Nomograms For Predicting The Overall Survival And Cancer-specific Survival Of Patients With Ovarian Carcinosarcoma Patients After Primary Surgery
Fang Ren, Shengtan Wang, Feifei Li, Jian Gao, Haoya Xu, Xianli Li, Liancheng Zhu
J. Cancer 2021; doi:10.7150/jca.63224; in press
[Author manuscript]

Colony stimulating factor-1 and its receptor in gastrointestinal malignant tumors
Hong-wu Li, Shi-lei Tang
J. Cancer 2021; doi:10.7150/jca.60379; in press
[Author manuscript]

MiR-211-5p inhibits the biological behaviors of colorectal cancer via SPARC-related growth factor pathways
Xiaoyu Wu, Yu Chen, Ya Zhu, Facai Cui
J. Cancer 2021; doi:10.7150/jca.60269; accepted
[Author manuscript]

INPP4B exerts a dual role in gastric cancer progression and prognosis
Youliang Wu, Xiaodong Wang, Yida Lu, Huizhen Wang, Mingliang Wang, Yexiang You, Xiaoli Su, Dengqun Sun, Yanjun Sun, Yongxiang Li
J. Cancer 2021; doi:10.7150/jca.58397; in press
[Author manuscript]

Long non-coding RNA MAGI2-AS3 inactivates STAT3 pathway to inhibit prostate cancer cell proliferation via acting as a microRNA-424-5p sponge
Yi Hou, Yan Zhang, Huaiwei Zhang, Zhou Sun, Xiangdi Meng, Zhixin Wang
J. Cancer 2021; doi:10.7150/jca.60749; accepted
[Author manuscript]

GOLM1 Drives Colorectal Cancer Metastasis by Regulating Myeloid-derived Suppressor Cells
Yunzhi Dang, Jiao Yu, Shuhong Zhao, Long Jin, Ximing Cao, Qing Wang
J. Cancer 2021; doi:10.7150/jca.61567; in press
[Author manuscript]

EZH2-mediated epigenetic suppression of lncRNA PCAT18 predicts a poor prognosis and regulates the expression of p16 by interacting with miR-570a-3p in gastric cancer
Liangjun Zhu, Chongguo Zhang, Jiao Xue, Xuezhi He, Dandan Yin, Qingqing Zhu, Yongqian Shu, Wei De
J. Cancer 2021; doi:10.7150/jca.63415; in press
[Author manuscript]

Association between Platelet Count with 1-year Survival in Patients with Cancer Cachexia
Yu-Ying Liu, Yi-Zhong Ge, Qin-Qin Li, Guo-Tian Ruan, Qi Zhang, Xi Zhang, Meng Tang, Meng-Meng Song, Xiao-Wei Zhang, Xiang-Rui Li, Kang-Ping Zhang, Ming Yang, Chun-Lei Hu, Tong Liu, Hai-Lun Xie, Yong-Bing Chen, Kai-Ying Yu, Ming-Hua Cong, Wei Li, Zheng-Ping Wang, Han-Ping Shi
J. Cancer 2021; doi:10.7150/jca.62788; accepted
[Author manuscript]

RNF114 silencing inhibits the proliferation and metastasis of gastric cancer
Zongfeng Feng, Leyan Li, Qingwen Zeng, Yang Zhang, Yi Tu, Wenzheng Chen, Xufeng Shu, Ahao Wu, Jianbo Xiong, Yi Cao, Zhengrong Li
J. Cancer 2021; doi:10.7150/jca.62033; accepted
[Author manuscript]

Plasma microRNA panel predicts early tumor recurrence in patients with hepatocellular carcinoma after liver transplantation
Ao Huang, De-Zhen Guo, Yu-Peng Wang, Guo-Huan Yang, Qi-Man Sun, Xin Zhang, Yi-Feng He, Kang Song, Xiao-Wu Huang, Xin-Rong Yang, Jia Fan, Jian Zhou, Jie Hu
J. Cancer 2021; doi:10.7150/jca.59612; in press
[Author manuscript]

Cold exposure and Capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling
Jing-chun Qin, Wei-tao YuHui-xuan, Yu-qi Liang, Feifei-Nong
J. Cancer 2021; doi:10.7150/jca.61098; accepted
[Author manuscript]

Systemic sequential therapy of CisGem, Tislelizumab and Lenvatinib for preoperative advanced intrahepatic cholangiocarcinoma transformation therapy
Yuan Ding, Xin Han, Zhongquan Sun,Jinlong Tang, Yingsheng Wu, Weilin Wang
J. Cancer 2021; doi:10.7150/jca.61030; accepted
[Author manuscript]

The functional role of Pescadillo ribosomal biogenesis factor 1 in cancer
Yong-Zhi Li, Cheng Zhang, Jun-Peng Pei, Wan-Chuan Zhang, Chun-Dong Zhang, Dong-Qiu Dai
J. Cancer 2021; doi:10.7150/jca.58982; accepted
[Author manuscript]

Histone methyltransferase KMT2D regulated H3K4 methylation and was involved in the pathogenesis of ovarian cancer
Ming Li, Mengdie Shi, Ying Xu, Jianping Qiu, Qing Lv
J. Cancer 2021; doi:10.7150/jca.56753; accepted
[Author manuscript]

Serum exosomal miR-34a as a potential biomarker for the diagnosis and prognostic of hepatocellular carcinoma
Shuying Chen, Yinqi Mao, Wei Chen, Chenbin Liu, Han Wu, Jingjun Zhang, Shenghao Wang, Chengpan Wang, Yong Lin, Yuan Lv
J. Cancer 2021; doi:10.7150/jca.57205; accepted
[Author manuscript]

The therapeutic effects of acupuncture and electroacupuncture on cancer-related symptoms and side-effects
Qiu-Qin Han, Yi Fu, Jia-Mei Le, Yu-Jie Ma, Xin-Dong Wei, Hou-Lin Ji, Haochen Jiang, Yueqiu Gao, Hailong Wu
J. Cancer 2021; doi:10.7150/jca.55803; in press
[Author manuscript]

SLC25A21 suppresses cell growth in bladder cancer via the reactive oxygen species-mediated mitochondrion-dependent apoptosis pathway
Yong Wang, Jiawen Gao, Shasha Hu, Weiting Zeng, Hui Chen, Liankun Sun, Shuang Wang
J. Cancer 2021; doi:10.7150/jca.50906; accepted
[Author manuscript]

EVALUATION OF ANTI-CANCER FUNCTION OF TRANSGENIC HEMATOPOIETIC NATURAL KILLER CELLS
Alireza Pirahmadiana, Shaharudin Abdul Razak, Shamsul Azlin B Ahmad Shamsuddin
J. Cancer 2021; doi:10.7150/jca.48343; accepted
[Author manuscript]

Multimodality MRI-based Prediction Model for Histologic Grade of Hepatocellular Carcinoma
Baolin Wu, Fei Jia, Xuekun Li, Kaiyu Wang, Dongming Han, Zhiyun Jia
J. Cancer 2021; doi:10.7150/jca.49029; accepted
[Author manuscript]

The association between sites of distant metastases and overall survival in cervical cancer
Ce Wang, Zhenyi Xu, Jiali Song, Yuhong Lu, Meng Wang, Yan Hou
J. Cancer 2021; doi:10.7150/jca.41046; accepted
[Author manuscript]


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