J Cancer 2011; 2:324-328. doi:10.7150/jca.2.324 This volume Cite

Short Report

Targeting EGFR in Triple Negative Breast Cancer

Naoto T. Ueno1,2, Dongwei Zhang1,2 ✉

1. Breast Cancer Translational Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;
2. Department of Breast Medical Oncology, Morgan Welch Inflammatory Breast Cancer Research Program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Citation:
Ueno NT, Zhang D. Targeting EGFR in Triple Negative Breast Cancer. J Cancer 2011; 2:324-328. doi:10.7150/jca.2.324. https://www.jcancer.org/v02p0324.htm
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Abstract

Our preliminary data show that erlotinib inhibits Triple-negative breast cancer (TNBC) in a xenograft model. However, inhibition of metastasis by erlotinib is accompanied by nonspecific effects because erlotinib can inhibit other kinases; thus, more direct targets that regulate TNBC metastasis need to be identified to improve its therapeutic efficacy.

Keywords: triple negative breast cancer, tyrosine kinase inhibitor, EGFR, erlotinib, metastasis


Citation styles

APA
Ueno, N.T., Zhang, D. (2011). Targeting EGFR in Triple Negative Breast Cancer. Journal of Cancer, 2, 324-328. https://doi.org/10.7150/jca.2.324.

ACS
Ueno, N.T.; Zhang, D. Targeting EGFR in Triple Negative Breast Cancer. J. Cancer 2011, 2, 324-328. DOI: 10.7150/jca.2.324.

NLM
Ueno NT, Zhang D. Targeting EGFR in Triple Negative Breast Cancer. J Cancer 2011; 2:324-328. doi:10.7150/jca.2.324. https://www.jcancer.org/v02p0324.htm

CSE
Ueno NT, Zhang D. 2011. Targeting EGFR in Triple Negative Breast Cancer. J Cancer. 2:324-328.

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