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Volume 17 (9); 2026

Research Papers

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Subtype-Dependent Transcriptional Coupling Between DNMT1 and E2F-Linked Proliferative Programs in Breast Cancer: A Dual-Cohort Transcriptomic Analysis Ping Xiao, Yiqun Xie, Ruijie Niu, Ming Shan, Zhiwu Dong, Yang Shi J. Cancer 2026; 17(9): 1547-1557. doi:10.7150/jca.134046 Full text PDF


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Perioperative coagulation profiling and postoperative lower-extremity venous thrombosis risk prediction in glioma patients Ping Pu, Miao Yang, Hong Zhou, Yan Xiang, Shuai Wang, Shengqing Lv, Wei Yang J. Cancer 2026; 17(9): 1558-1569. doi:10.7150/jca.136435 Full text PDF


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Analysis of single nucleotide polymorphism of SYNE1 gene in Oral squamous cell carcinoma Ming-Ju Hsieh, Hsin-Yu Ho, Yu-Sheng Lo, Bharath Kumar Velmurugan, Shanmugavadivu Muthusamy, Min-Yun Kao, Chia-Chieh Lin, Yi-Ching Chuang, Mu-Kuan Chen J. Cancer 2026; 17(9): 1570-1575. doi:10.7150/jca.139098 Full text PDF


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Prognostic Value of the Prognostic Nutritional Index in Patients with Metastatic Melanoma Mustafa Sahbazlar, Hikmet Akar, Atike Pinar Erdogan, Ferhat Ekinci J. Cancer 2026; 17(9): 1576-1582. doi:10.7150/jca.136818 Full text PDF


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Cofilin/RhoA and CREB synergistically promote invasion and migration of polyploid giant cancer cells in colorectal cancer Yidi Ning, Kai Liu, Jing Xu, Liechen Ji, Shiwu Zhang J. Cancer 2026; 17(9): 1583-1599. doi:10.7150/jca.138960 Full text PDF


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Chronically Established ρ0 Cancer Cells Exhibit Shared Stemness-Associated and Aggressive Phenotypes Across Multiple Cancer Cell Lines Yu-Seon Han, Myeong-Eun Jegal, Su Yeon Lee, Joung-Sun Park, Yung-Jin Kim J. Cancer 2026; 17(9): 1615-1625. doi:10.7150/jca.138124 Full text PDF


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Smoking-Associated Enrichment of CXCL13+ Tfh Cells and VCAM1+ Fibroblasts Is Linked to Tertiary Lymphoid Structure Formation in Lung Adenocarcinoma Yong Jun Choi, Chi Young Kim, Eun Young Kim, Sang Hoon Lee, Min Kyung Park, Yoon Soo Chang J. Cancer 2026; 17(9): 1626-1638. doi:10.7150/jca.138884 Full text PDF


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Integrated Pan-Cancer, Single-Cell, and Spatial Transcriptomic Analyses Identify ZDHHC12 as a Biomarker Associated with Macrophage Infiltration and the Immune Landscape in Glioma Chao Zhang, Da Teng, Yu Wang, Shiqiang Hou, Wenjun Zhang, Ning Lin J. Cancer 2026; 17(9): 1653-1670. doi:10.7150/jca.136931 Full text PDF

Reviews

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Overcoming Resistance to PARP Inhibitors in BRCA-Mutated Cancers: Mechanisms and Therapeutic Strategies Jiahui Guo, Yilei Wang, Jie Li, Zhitao Jiang J. Cancer 2026; 17(9): 1600-1614. doi:10.7150/jca.130206 Full text PDF


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Liquid Biopsy and Nonendoscopic Biomarkers for Precision Early Detection of Esophageal Cancer: Evidence, Risk Stratification and Translational Challenges Fangzheng Han, Huaimin Liu J. Cancer 2026; 17(9): 1639-1652. doi:10.7150/jca.140909 Full text PDF


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Regulatory roles of E3 ubiquitin ligase RNF128 in inflammatory diseases and tumors Qiuxiang Xiao, Qidong Liu, Jing Wei, Dalang Yu J. Cancer 2026; 17(9): 1671-1683. doi:10.7150/jca.138010 Full text PDF


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Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges Haixia Gao, Yuan Fang, Pingjing Zhang, Qijun Qian J. Cancer 2026; 17(9): 1684-1697. doi:10.7150/jca.134677 Full text PDF

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