J Cancer 2014; 5(1):69-78. doi:10.7150/jca.7048 This issue


Future Directions for Monitoring Treatment Responses in Breast Cancer

Matthew P. Shupe1✉, Lindsey J. Graham1, Erika J. Schneble2, Frederick L. Flynt1, Michael N. Clemenshaw3, Aaron D. Kirkpatrick4, Alexander Stojadinovic5, George E. Peoples6, Nathan M. Shumway1

1. Department of Hematology/Oncology
2. Department of Surgery
3. Department of Nuclear Medicine
4. Department of Diagnostic Radiology
5. Department of Surgical Oncology, San Antonio Military Medical Center (SAMMC), Brooke Army Medical Center, 3551 Roger Brooke Dr., Ft. Sam Houston, TX 78234, USA
6. Department of Surgical Oncology, Walter Reid National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20889, USA

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Shupe MP, Graham LJ, Schneble EJ, Flynt FL, Clemenshaw MN, Kirkpatrick AD, Stojadinovic A, Peoples GE, Shumway NM. Future Directions for Monitoring Treatment Responses in Breast Cancer. J Cancer 2014; 5(1):69-78. doi:10.7150/jca.7048. Available from https://www.jcancer.org/v05p0069.htm

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In the prior review, we outlined the current standard of care for monitoring treatment responses in breast cancer and discussed the many challenges associated with these strategies. We described the challenges faced in common clinical settings such as the adjuvant setting, neoadjuvant setting, and the metastatic setting. In this review, we will expand upon future directions meant to overcome several of these current challenges. We will also explore several new and promising methods under investigation to enhance how we monitor treatment responses in breast cancer. Furthermore, we will highlight several new technologies and techniques for monitoring breast cancer treatment in the adjuvant, neoadjuvant and metastatic setting.

Keywords: breast cancer, treatment monitoring, future directions, adjuvant, neoadjuvant, metastatic