J Cancer 2014; 5(6):433-445. doi:10.7150/jca.9360 This issue

Research Paper

A Multifactoral Analysis of 1452 Patients for Smoking Sensation. An Outpatient Lab Experience

Theodora Tsiouda1,2, Paul Zarogoulidis2✉, Dimitris Petridis3, Nikolaos Pezirkianidis4, Ioannis Kioumis2, Lonny Yarmus5, Haidong Huang6, Qiang Li6, Wolfgang Hohenforst-Schmidt7, Konstantinos Porpodis2, Dionysios Spyratos2, Kosmas Tsakiridis2, Georgia Pitsiou2, Theodoros Kontakiotis2, Paraskevi Argyropoulou2, George Kyriazis2, Konstantinos Zarogoulidis2

1. Internal Medicine Department, ``Theageneio`` Anticancer Hospital, Thessaloniki, Greece.
2. Pulmonary Department-Oncology Unit, ``G. Papanikolaou`` General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
3. Department of Food Technology, School of Food Technology and Nutrition, Alexander Technological Educational Institute, Thessaloniki, Greece.
4. Surgery Department, Private Cabinet, Serres, Greece.
5. Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, U.S.A.
6. Department of Respiratory Diseases Shanghai Hospital, II Military University Hospital, Shanghai, China.
7. II Medical Department, General Hospital of Coburg, University of Wuerzburg, Coburg, Germany.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
Tsiouda T, Zarogoulidis P, Petridis D, Pezirkianidis N, Kioumis I, Yarmus L, Huang H, Li Q, Hohenforst-Schmidt W, Porpodis K, Spyratos D, Tsakiridis K, Pitsiou G, Kontakiotis T, Argyropoulou P, Kyriazis G, Zarogoulidis K. A Multifactoral Analysis of 1452 Patients for Smoking Sensation. An Outpatient Lab Experience. J Cancer 2014; 5(6):433-445. doi:10.7150/jca.9360. Available from https://www.jcancer.org/v05p0433.htm

File import instruction


Smoking habit is held responsible for several respiratory and metabolic diseases. Data from 1452 patients were recorded from our outpatient laboratory. The following parameters were recorded within several follow ups of our patients; smoking habit, respiratory functions, smoking cessation questionnaires, and administered drugs. The treatment administered to smokers throughout the period of inspection seems to also have a significant effect on dependence. In fact, varelicline causes a 50% reduction in smoking dependence in regards to nicotine substitutes (odds ratio: 0.48 (0.31-0,74), p=0.001) so displaying a substantial preponderance on the choice to fight smoking dependence.

Keywords: smoking sensation, COPD, Asthma, CAD.