Phycocyanin: A Potential Drug for Cancer Treatment

Jiang, Liangqian; Wang, Yujuan; Yin, Qifeng; Liu, Guoxiang; Liu, Huihui; Huang, Yajing; Li, Bing

doi:10.7150/jca.21058

International Journal of Biological Sciences

International Journal of Medical Sciences

Theranostics

Journal of Genomics

Nanotheranostics

open access Global reach, higher impact

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J Cancer 2017; 8(17):3416-3429. doi:10.7150/jca.21058 This issue Cite

Review

Phycocyanin: A Potential Drug for Cancer Treatment

Liangqian Jiang^1*, Yujuan Wang^1#, Qifeng Yin^1#, Guoxiang Liu^1#, Huihui Liu^1#, Yajing Huang^2#, Bing Li^1✉

1. Department of Genetics and Cell Biology, Basic medical college, 308 Ningxia Road, Qingdao University, Qingdao, China, 266071;
2. Basic medical college, 308 Ningxia Road, Qingdao University, Qingdao, China, 266071.
* The first author: Liangqian Jiang Email: jiang8014@163.com
# Contributed equally

Citation:

Jiang L, Wang Y, Yin Q, Liu G, Liu H, Huang Y, Li B. Phycocyanin: A Potential Drug for Cancer Treatment. J Cancer 2017; 8(17):3416-3429. doi:10.7150/jca.21058. https://www.jcancer.org/v08p3416.htm

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Abstract

Phycocyanin isolated from marine organisms has the characteristics of high efficiency and low toxicity, and it can be used as a functional food. It has been reported that phycocyanin has anti-oxidative function, anti-inflammatory activity, anti-cancer function, immune enhancement function, liver and kidney protection pharmacological effects. Thus, phycocyanin has an important development and utilization as a potential drug, and phycocyanin has become a new hot spot in the field of drug research. So far, there are more and more studies have shown that phycocyanin has the anti-cancer effect, which can block the proliferation of cancer cells and kill cancer cells. Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, thereby phycocyanin can serve as a promising anti-cancer agent. This review discusses the therapeutic use of phycocyanin and focuses on the latest advances of phycocyanin as a promising anti-cancer drug.

Keywords: Phycocyanin, Apoptosis, Autophagy, Cancer, Cell cycle arrest.

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APA

Jiang, L., Wang, Y., Yin, Q., Liu, G., Liu, H., Huang, Y., Li, B. (2017). Phycocyanin: A Potential Drug for Cancer Treatment. Journal of Cancer, 8(17), 3416-3429. https://doi.org/10.7150/jca.21058.

ACS

Jiang, L.; Wang, Y.; Yin, Q.; Liu, G.; Liu, H.; Huang, Y.; Li, B. Phycocyanin: A Potential Drug for Cancer Treatment. J. Cancer 2017, 8 (17), 3416-3429. DOI: 10.7150/jca.21058.

NLM

Jiang L, Wang Y, Yin Q, Liu G, Liu H, Huang Y, Li B. Phycocyanin: A Potential Drug for Cancer Treatment. J Cancer 2017; 8(17):3416-3429. doi:10.7150/jca.21058. https://www.jcancer.org/v08p3416.htm

CSE

Jiang L, Wang Y, Yin Q, Liu G, Liu H, Huang Y, Li B. 2017. Phycocyanin: A Potential Drug for Cancer Treatment. J Cancer. 8(17):3416-3429.

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