J Cancer 2018; 9(16):2946-2952. doi:10.7150/jca.25539 This issue Cite

Research Paper

The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm)

Wenwu Ling1*, Manni Wang2*, Xuelei Ma2, Tingting Qiu1, Jiawu Li1, Qiang Lu1✉, Yan Luo1✉

1. Department of Ultrasound, West China Hospital of Sichuan University, Chengdu 610041, China
2. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China
*: these authors contributed equally to this work.

Citation:
Ling W, Wang M, Ma X, Qiu T, Li J, Lu Q, Luo Y. The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). J Cancer 2018; 9(16):2946-2952. doi:10.7150/jca.25539. https://www.jcancer.org/v09p2946.htm
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Abstract

To evaluate the diagnostic accuracy of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) for patients at risk for hepatocellular carcinoma with hepatic nodules (≤2cm). We retrospectively evaluated 56 CEUS exam records of hepatic nodules (≤2cm) performed between January 2015 and July 2016 at West China hospital. Each nodule was classified into a LI-RADS-CEUS category by two radiologists according to imaging features. The ultimate CEUS categories were then compared with pathological reports and their correlation was then calculated. Inter-observer agreement for LI-RADS between reader A and B was κ, 0.690, illustrating good consistency. The diagnostic accuracy of LR-5 on hepatocellular carcinoma (HCC) was 86.49% but 11.11% for LR-M. LI-RADS-CEUS is a potential standardized categorization system for high-risk HCC patients but might also increase the false-negative diagnosis of nodules of less than 2cm.

Keywords: Contrast-enhanced ultrasound, Liver imaging reporting and data system, and Small hepatic nodules


Citation styles

APA
Ling, W., Wang, M., Ma, X., Qiu, T., Li, J., Lu, Q., Luo, Y. (2018). The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). Journal of Cancer, 9(16), 2946-2952. https://doi.org/10.7150/jca.25539.

ACS
Ling, W.; Wang, M.; Ma, X.; Qiu, T.; Li, J.; Lu, Q.; Luo, Y. The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). J. Cancer 2018, 9 (16), 2946-2952. DOI: 10.7150/jca.25539.

NLM
Ling W, Wang M, Ma X, Qiu T, Li J, Lu Q, Luo Y. The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). J Cancer 2018; 9(16):2946-2952. doi:10.7150/jca.25539. https://www.jcancer.org/v09p2946.htm

CSE
Ling W, Wang M, Ma X, Qiu T, Li J, Lu Q, Luo Y. 2018. The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). J Cancer. 9(16):2946-2952.

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