Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum

Wang, Mingming; Zhang, Yufu; Liu, Min; Jia, Yuna; He, Jing; Xu, Xiangrong; Shi, Haiyan; Zhang, Yunqing; Zhang, Jing; Liu, Yusi

doi:10.7150/jca.105504

Top

International Journal of Biological Sciences

International Journal of Medical Sciences

Theranostics

Journal of Genomics

Nanotheranostics

open access Global reach, higher impact

PDF

J Cancer 2024; 15(20):6808-6810. doi:10.7150/jca.105504 This issue Cite

Erratum

Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum

Mingming Wang^1#, Yufu Zhang^2#, Min Liu^3#, Yuna Jia¹, Jing He⁴, Xiangrong Xu¹, Haiyan Shi¹, Yunqing Zhang⁴, Jing Zhang¹, Yusi Liu¹

1. Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an 716000, Shaanxi Province, China
2. Department of Hepatobiliary Surgery, Affiliated Hospital of Yan'an University, Yan'an 716000, Shaanxi Province, China
3. Department of Pathology, Affiliated Hospital of Yan'an University, Yan'an 716000, Shaanxi Province, China
4. Laboratory of Obstetrics and Gynecology, Affiliated Hospital of Yan'an University, Yan'an, 716000 Shaanxi Province, China
^#These authors equally contributed to the paper.

Citation:

Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y. Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum. J Cancer 2024; 15(20):6808-6810. doi:10.7150/jca.105504. https://www.jcancer.org/v15p6808.htm

Other styles

Corrected-article in J Cancer, Volume 14, 611

In the original version of our article, there was an error in Figure 5A, 6A, 7E. Specifically, the Immunocytochemical Staining (ICC) for U251 STAT3, P-STAT3 C9, VEGFA C9 and U87-MG MCL-1 was used wrong in Figure 5A and Figure 6A, so we replaced with the correct band, and the western blot band for RG-2 actin was used wrong in Figure 7E, so we replaced with the correct band. The correct image is provided below. This correction will not affect the results and conclusions. We are deeply sorry and sincerely apologize for the error and for any inconvenience that may cause to the readers and the editors of this journal.

Figure 5

Changes in STAT3 signaling pathway in U251, U87-MG, LN-428, and RG-2 cells after 48 h treatment without (CON) or with (C9) HUC-MSCs supernatants. (A) ICC examination (× 20 and × 40), and (B) Western Blot analyses of IL-6, JAK2, STAT3, p-STAT3, and PIAS3. β-actin was used as a qualitative and quantitative control. CON, 0 mg/ml HUC-MSCs supernatants; C9, 9 mg/ml HUC-MSCs supernatants. *P < 0.05, **P < 0.01 and ***P < 0.001 vs CON group; the error bars, the mean ± standard deviation.

Figure 6

Examinations of MCL-1, Survivin, VEGFA, c-Myc, LC3 ӀӀ/Ӏ and Beclin-1 expression in U251, U87-MG, LN-428, and RG-2 cells without (CON) and with (C9) HUC-MSCs supernatants treatments for 48 h. (A) ICC examination (× 20 and × 40) and (B) Western blot analyses of MCL-1, Survivin, VEGFA, and c-Myc. β-actin was used as a qualitative and quantitative control. (C) IF experiments were performed by laser confocal microscopy (× 20) to examine the expression of the autophagy-related proteins LC3 ӀӀӀ/Ӏ and Beclin-1. and (D) Western Blot analyses of LC3 ӀӀ/Ӏ and Beclin-1. β-actin was used as a qualitative and quantitative control. CON, 0 mg/ml HUC-MSCs supernatansts; C9, 9 mg/ml HUC-MSCs supernatants. *P < 0.05, **P < 0.01 and ***P < 0.001 vs CON group; the error bars, the mean ± standard deviation.

Figure 7

Alterations in STAT3 signaling pathway after 48h of STAT3 inhibitor C188-9 applied to U251, U87-MG, LN-428 and RG-2 cells. (A) CCK-8 assays showing the effect of C188-9 in U251, U87-MG, LN-428 and RG-2 cells. (B) CCK-8 assays showing the effect of HUC-MSCs supernatant or/and C188-9 in U251, U87-MG, LN-428 and RG-2 cells. (C) Transwell Migration assay. (D) Four GBM cell lines were statistically analysed for migration. (E) Western blot analyses of STAT3/p-STAT3 and downstream related proteins Survivin, MCL-1 and c-Myc expression. β-actin was used as a qualitative and quantitative control. CON, Blank control group; C9, 9 mg/ml HUC-MSCs supernatant; C188-9: N-(1ʹ,2-Dihydroxy-1,2ʹ-binaphthalen-4ʹ-yl)-4-methoxybenzenesulfonamide, STAT3 inhibitor; *P < 0.05, **P < 0.01 and ***P < 0.001 vs CON group; the error bars, the mean ± standard deviation.

Author contact

Corresponding authors: Yusi Liu, Department of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an 716000, Shaanxi Province, China; E-mail addresses: zhangyq2881123com (Y. Zhang), yadxzjedu.cn (J. Zhang), lys910615com (Y. Liu), Tel: +86-0911-2332662

Published 2024-11-2

Citation styles

APA

Wang, M., Zhang, Y., Liu, M., Jia, Y., He, J., Xu, X., Shi, H., Zhang, Y., Zhang, J., Liu, Y. (2024). Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum. Journal of Cancer, 15(20), 6808-6810. https://doi.org/10.7150/jca.105504.

ACS

Wang, M.; Zhang, Y.; Liu, M.; Jia, Y.; He, J.; Xu, X.; Shi, H.; Zhang, Y.; Zhang, J.; Liu, Y. Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum. J. Cancer 2024, 15 (20), 6808-6810. DOI: 10.7150/jca.105504.

NLM

CSE

Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y. 2024. Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells: Erratum. J Cancer. 15(20):6808-6810.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.