J Cancer 2013; 4(6):514-518. doi:10.7150/jca.6949 This issue
1. Department of Urology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan;
2. Department of Urology, Sakai Hospital Kinki University Faculty of Medicine, Sakai, Osaka, Japan;
3. Department of Urology, Mimihara General Hospital, Sakai, Osaka, Japan;
4. Department of Urology, Saiseikai Tondabayashi Hospital, Tondabayashi, Osaka, Japan;
5. Department of Urology, NTT West Osaka Hospital, Osaka, Osaka, Japan;
6. Department of Urology, Izumiotsu Municipal Hospital, Izumiotsu, Osaka, Japan.
Background: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery versus immediate surgery.
Methods: We reviewed the clinical records of 328 patients with SRM ≦ 4cm at diagnosis, who underwent delayed or immediate surgical intervention from January 2000 to December 2011. Radiographic evaluation using CT scan and MRI were performed at least every 6 months and the tumor size was determined at least twice in the delayed surgery group.
Results: A total of 292 RCC patients with pT1aN0M0 were identified; among them, 32 patients had been managed with delayed surgery intervention. No statistically significant difference was observed in overall survival rate (OSR) and cancer recurrence-free rate (CRFR). But cancer-specific survival rate (CSSR) was significantly lower in the delayed surgery group (p=0.0002).
Conclusions: The overall survival rate of delayed surgery was not inferior compared with that after immediate surgery. Delayed surgery intervention for SRMs is a treatment option in the current study.
Keywords: renal cell carcinoma, small renal mass, delayed surgery, immediate surgery, natural history.