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Volume 12 (9); 2021

Research Papers

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Proteasome Complexes and Their Heterogeneity in Colorectal, Breast and Pancreatic Cancers
Diana Zagirova, Rebecca Autenried, Morgan E. Nelson, Khosrow Rezvani
J. Cancer 2021; 12(9): 2472-2487. doi:10.7150/jca.52414
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Impact of transformation on the survival of patients diagnosed with follicular lymphoma that progressed within 24 months
Sang Eun Yoon, Junhun Cho, Won Seog Kim, Seok Jin Kim
J. Cancer 2021; 12(9): 2488-2497. doi:10.7150/jca.54434
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Diagnostic roles of proliferative markers in pathological Grade of T1 Urothelial Bladder Cancer
Jianping Yang, Chunjun Li, Yong Tang, Fang Guo, Yu Chen, Wenqi Luo, Xiaoyu Chen, Yun Ma, Lixia Zeng
J. Cancer 2021; 12(9): 2498-2506. doi:10.7150/jca.52336
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Socioeconomic factors are associated with the prognosis of Thyroid Cancer
Yu Li, Da Huang, Baoxin Wang, Wei Mao, Xinwei Chen, Pin Dong
J. Cancer 2021; 12(9): 2507-2512. doi:10.7150/jca.52329
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Has the increase in the regional nodes evaluated improved survival rates for patients with locoregional colon cancer?
Zhongyi Zhou, Hong Zhu, Wenxue Liu, Fengbo Tan, Qian Pei, Lilan Zhao, Chenglong Li, Dan Wang, Yuan Zhou, Huan Peng, Haiping Pei, Yuqiang Li
J. Cancer 2021; 12(9): 2513-2525. doi:10.7150/jca.52352
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Systematic analysis of the function and prognostic value of RNA binding proteins in Colon Adenocarcinoma
Xuewei Qi, Zeyu Liu, Qiaoli Zhang, Ming Yang, Yuxiang Wan, Jinchang Huang, Lin Xu
J. Cancer 2021; 12(9): 2537-2549. doi:10.7150/jca.50407
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Overexpression of ERCC3 is associated with poor prognosis in patients with pancreatic cancer
Shujie Wang, Wenjing Liu, Yueli Ni, Lifeng Wang, Yuzhi Zhu, Qiong Shi, Zihan Yi, Wenjie Wang, Lili Liu, Lijuan Yang, Yingmin Kuang, Yuechun Zhu, Qiao Zhang, Zhe Yang
J. Cancer 2021; 12(9): 2550-2559. doi:10.7150/jca.54576
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Intratumoral Treatment with Chemotherapy and Immunotherapy for NSCLC with EBUS-TBNA 19G
Paul Zarogoulidis, Wolfgang Hohenforst-Schmidt, Haidong Huang, Jun Zhou, Qin Wang, Xiangqi Wang, Ying Xia, Yinfeng Ding, Chong Bai, Christoforos Kosmidis, Konstantinos Sapalidis, Chrysanthi Sardeli, Kosmas Tsakiridis, Bojan Zaric, Tomi Kovacevic, Vladimir Stojsic, Tatjana Sarcev, Daliborka Bursac, Biljana Kukic, Sofia Baka, Evagelia Athanasiou, Dimitrios Hatzibougias, Electra Michalopoulou-Manoloutsiou, Savvas Petanidis, Dimitris Drougas, Konstantinos Drevelegas, Dimitris Paliouras, Nikolaos Barbetakis, Anastasios Vagionas, Lutz Freitag, Aimilios Lallas, Ioannis Boukovinas, Dimitris Petridis, Aris Ioannidis, Dimitris Matthaios, Konstantinos Romanidis, Chrisanthi Karapantzou
J. Cancer 2021; 12(9): 2560-2569. doi:10.7150/jca.55322
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Circadian rhythm-associated clinical relevance and Tumor Microenvironment of Non-small Cell Lung Cancer
Ming Li, Zhencong Chen, Tian Jiang, Xiaodong Yang, Yajing Du, Jiaqi Liang, Lin Wang, Junjie Xi, Miao Lin, Mingxiang Feng
J. Cancer 2021; 12(9): 2582-2597. doi:10.7150/jca.52454
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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TTC36 inactivation induce malignant properties via Wnt-β-catenin pathway in gastric carcinoma
Lei Song, Xiaonong Guo, Fei Zhao, Wei Wang, Zhifang Zhao, Long Jin, Chengli Wu, Jibin Yao, Zhongren Ma
J. Cancer 2021; 12(9): 2598-2609. doi:10.7150/jca.47292
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Circular RNA hsa_circ_0000700 promotes cell proliferation and migration in Esophageal Squamous Cell Carcinoma by sponging miR-1229
Jun Fang, Wen Hao Ji, Fang Zheng Wang, Tie Ming Xie, Lei Wang, Zhen Fu Fu, Zhun Wang, Feng Qin Yan, Qi Liang Shen, Zhi Min Ye
J. Cancer 2021; 12(9): 2610-2623. doi:10.7150/jca.47112
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Region-specific Risk Factors for Pelvic Lymph Node Metastasis in Patients with Stage IB1 Cervical Cancer
Jing Zhao, Jing Cai, Hongbo Wang, Weihong Dong, Yuan Zhang, Shaohai Wang, Xiaoqi He, Si Sun, Yuhui Huang, Bangxing Huang, Kay C. Willborn, Ping Jiang, Zehua Wang
J. Cancer 2021; 12(9): 2624-2632. doi:10.7150/jca.53215
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Real-world data combined with studies on Regulatory B Cells for newly diagnosed Multiple Myeloma from a tertiary referral Hospital in South-Western China
Zhongqing Zou, Tingting Guo, Jian Cui, Wenjiao Tang, Yan Li, Fangfang Wang, Tian Dong, Yunfan Yang, Yan Feng, Matthew Ho, Li Zhang, Ling Pan, Ting Niu
J. Cancer 2021; 12(9): 2633-2642. doi:10.7150/jca.53209
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Bevacizumab Plays a double-edged role in Neoadjuvant Therapy for Non-metastatic Breast Cancer: A Systemic Review and Meta-Analysis
XinJie Chen, Yu Gao, GanLin Zhang, BingXue Li, TingTing Ma, YunFei Ma, XiaoMin Wang
J. Cancer 2021; 12(9): 2643-2653. doi:10.7150/jca.53303
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Overexpression of Galectin10 Predicts a Better Prognosis in Human Ovarian Cancer
Wenxiao Jiang, Mandika Chetry, Shuya Pan, Longyi Wang, Xueqiong Zhu
J. Cancer 2021; 12(9): 2654-2664. doi:10.7150/jca.54595
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Methylated SFRP2 and SDC2 in stool specimens for Colorectal Cancer early detection: A cost-effective strategy for Chinese population
Guodong Zhao, Xiaoyu Liu, Yi Liu, Yong Ma, Jun Yang, Hui Li, Shangmin Xiong, Sujuan Fei, Minxue Zheng, Xiangwei Zhao
J. Cancer 2021; 12(9): 2665-2672. doi:10.7150/jca.52478
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Promoter hypermethylation of early B cell factor 1 (EBF1) is associated with cholangiocarcinoma progression
Napat Armartmuntree, Apinya Jusakul, Chadamas Sakonsinsiri, Watcharin Loilome, Somchai Pinlaor, Piti Ungarreevittaya, Chern Han Yong, Anchalee Techasen, Kanokwan Imtawil, Ratthaphol Kraiklang, Nattawan Suwannakul, Waleeporn Kaewlert, Timpika Chaiprasert, Raynoo Thanan, Mariko Murata
J. Cancer 2021; 12(9): 2673-2686. doi:10.7150/jca.52378
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Utility of Preoperative Inflammatory Markers to Distinguish Epithelial Ovarian Cancer from Benign Ovarian Masses
Lian Li, Jing Tian, Liwen Zhang, Luyang Liu, Chao Sheng, Yubei Huang, Hong Zheng, Fengju Song, Kexin Chen
J. Cancer 2021; 12(9): 2687-2693. doi:10.7150/jca.51642
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Serum Angiopoietin 2 acts as a diagnostic and prognostic biomarker in hepatocellular carcinoma
Junjie Ao, Tetsuhiro Chiba, Hiroaki Kanzaki, Kengo Kanayama, Shuhei Shibata, Akane Kurosugi, Terunao Iwanaga, Motoyasu Kan, Takafumi Sakuma, Na Qiang, Yaojia Ma, Ryuta Kojima, Yuko Kusakabe, Masato Nakamura, Kazufumi Kobayashi, Soichiro Kiyono, Naoya Kanogawa, Tomoko Saito, Ryo Nakagawa, Takayuki Kondo, Sadahisa Ogasawara, Eiichiro Suzuki, Shingo Nakamoto, Ryosuke Muroyama, Akinobu Tawada, Jun Kato, Tatsuo Kanda, Hitoshi Maruyama, Naoya Kato
J. Cancer 2021; 12(9): 2694-2701. doi:10.7150/jca.56436
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma
Wuping Yang, Jingcheng Zhou, Kenan Zhang, Lei Li, Yawei Xu, Kaifang Ma, Haibiao Xie, Lin Cai, Yanqing Gong, Kan Gong
J. Cancer 2021; 12(9): 2702-2714. doi:10.7150/jca.55113
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Integrating pre- and post-treatment Plasma Epstein-Barr Virus DNA levels for better prognostic prediction of Nasopharyngeal Carcinoma
Wanxia Li, Chao Yang, Zehong Lv, Junzheng Li, Zonghua Li, Xiaofei Yuan, Shuting Wu, Yue Yuan, Linchong Cui, Juan Lu, Jing Chen, Feipeng Zhao
J. Cancer 2021; 12(9): 2715-2722. doi:10.7150/jca.56397
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
Zhenqiang Sun, Bo Shao, Zaoqu Liu, Qin Dang, Yaxin Guo, Chen Chen, Yuying Guo, Zhuang Chen, Jinbo Liu, Shengyun Hu, Weitang Yuan, Quanbo Zhou
J. Cancer 2021; 12(9): 2723-2734. doi:10.7150/jca.55626
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Panel of Tumor-associated Autoantibodies for the Detection of Early-stage Breast Cancer
Chao-Qun Hong, Xue-Fen Weng, Xu-Chun Huang, Ling-Yu Chu, Lai-Feng Wei, Yi-Wei Lin, Liu-Yi Chen, Can-Tong Liu, Yi-Wei Xu, Yu-Hui Peng
J. Cancer 2021; 12(9): 2747-2755. doi:10.7150/jca.57019
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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SAA1 knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling
Huikai Zhang, Yang Xu, Gang Deng, Fanen Yuan, Yinqiu Tan, Lun Gao, Qian Sun, Yangzhi Qi, Kun Yang, Rongxin Geng, Hongxiang Jiang, Baohui Liu, Qianxue Chen
J. Cancer 2021; 12(9): 2756-2767. doi:10.7150/jca.48419
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cytokine-induced killer cells carrying recombinant oncolytic adenovirus expressing p21Ras scFv inhibited liver cancer
Fang Dai, Peng-Bo Zhang, Qiang Feng, Xin-Yan Pan, Shu-Ling Song, Jing Cui, Ju-Lun Yang
J. Cancer 2021; 12(9): 2768-2776. doi:10.7150/jca.51434
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Expression of Transcription Factors is Different in Papillary Thyroid Cancer Cells during TNF - α induced EMT
Nannan Lv, Fei Liu, Lan Cheng, Feng Liu, Jinsong Kuang
J. Cancer 2021; 12(9): 2777-2786. doi:10.7150/jca.53349
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Lignans intake and enterolactone concentration and prognosis of breast cancer: a systematic review and meta-analysis
Zhen Liu, Yin-Jiao Fei, Xin-Hui Cao, Di Xu, Wen-Juan Tang, Kai Yang, Wen-Xiu Xu, Jin-Hai Tang
J. Cancer 2021; 12(9): 2787-2796. doi:10.7150/jca.55477
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Exosome in Hepatocellular Carcinoma: an update
Wei Chen, Yinqi Mao, Chenbin Liu, Han Wu, Shuying Chen
J. Cancer 2021; 12(9): 2526-2536. doi:10.7150/jca.54566
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics
Yixin Wang, Jing Xiu, Chune Ren, Zhenhai Yu
J. Cancer 2021; 12(9): 2570-2581. doi:10.7150/jca.53134
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A snapshot of the PD-1/PD-L1 pathway
Chinmoy Ghosh, Gary Luong, Yue Sun
J. Cancer 2021; 12(9): 2735-2746. doi:10.7150/jca.57334
[Abstract] [Full text] [PDF] [PubMed] [PMC]