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Volume 12 (8); 2021

Research Papers

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Telomere shortening in head and neck cancer: association between DNA demethylation and survival
Satoshi Yamada, Kiyoshi Misawa, Masato Mima, Atsushi Imai, Daiki Mochizuki, Taiki Yamada, Daichi Shinmura, Junya Kita, Ryuji Ishikawa, Yuki Yamaguchi, Yuki Misawa, Hideya Kawasaki, Hiroyuki Mineta
J. Cancer 2021; 12(8): 2165-2172. doi:10.7150/jca.54760
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Genome-wide Expression Analysis Identifies the Association between SEC14L2 and Castration-resistant Prostate Cancer Survival
Shiyun Liu, Da Huang, Jingyi Huang, Jiaqi Yan, Tianhe Chen, Ning Zhang, Guangliang Jiang, Yi Gao, Danfeng Xu, Rong Na
J. Cancer 2021; 12(8): 2173-2180. doi:10.7150/jca.50299
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Proteomic profiling reveals a signature for optimizing prognostic prediction in Colon Cancer
Zezhi Shan, Dakui Luo, Qi Liu, Sanjun Cai, Renjie Wang, Yanlei Ma, Xinxiang Li
J. Cancer 2021; 12(8): 2199-2205. doi:10.7150/jca.50630
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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CDK1 serves as a novel therapeutic target for endometrioid endometrial cancer
Xue Ying, Xuan Che, Jianzhang Wang, Gen Zou, Qin Yu, Xinmei Zhang
J. Cancer 2021; 12(8): 2206-2215. doi:10.7150/jca.51139
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The genetic effect and molecular function of the SOCS5 in the prognosis of esophageal squamous cell carcinoma
Pei-Wen Yang, Ya-Han Chang, Li-Fan Wong, Ching-Ching Lin, Pei-Ming Huang, Min-Shu Hsieh, Jang-Ming Lee
J. Cancer 2021; 12(8): 2216-2229. doi:10.7150/jca.51806
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer
Tao Shen, Meiting Wang, Xiangting Wang
J. Cancer 2021; 12(8): 2230-2242. doi:10.7150/jca.52156
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MMP9 and IGFBP1 Regulate Tumor Immune and Drive Tumor Progression in Clear Cell Renal Cell Carcinoma
Tianbo Xu, Su Gao, Jingchong Liu, Yu Huang, Ke Chen, Xiaoping Zhang
J. Cancer 2021; 12(8): 2243-2257. doi:10.7150/jca.48664
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MicroRNA-32-5p inhibits epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting SMAD family 3
Jin-Xing Zhang, Wei Yang, Jun-Zheng Wu, Chun Zhou, Sheng Liu, Hai-Bin Shi, Wei-Zhong Zhou
J. Cancer 2021; 12(8): 2258-2267. doi:10.7150/jca.48387
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Long non-coding RNA RP11-379k17.4 derived microRNA-200c-3p modulates human endometrial cancer by targeting Noxa
Weijuan Xin, Xiaodong Gao, Peng Zhao, Taiyong Wang, Xue Ding, Qianyu Wu, Keqin Hua
J. Cancer 2021; 12(8): 2268-2274. doi:10.7150/jca.51023
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prognostic efficacy of the combination of the pretreatment systemic Immune-Inflammation Index and Epstein-Barr virus DNA status in locally advanced Nasopharyngeal Carcinoma Patients
Ying Xiong, Liang-Liang Shi, Li-Sheng Zhu, Qian Ding, Li Ba, Gang Peng
J. Cancer 2021; 12(8): 2275-2284. doi:10.7150/jca.52539
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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β-elemene enhances the antitumor activity of erlotinib by inducing apoptosis through AMPK and MAPK pathways in TKI-resistant H1975 lung cancer cells
Jue Wang, Cong Xu, Ying Chen, Le Shao, Ting Li, Xingxing Fan, Lili Yu, Ruonan Zhang, Bi Chen, Hongwei Chen, Xinbing Sui, Elaine Lai-Han Leung, Qibiao Wu
J. Cancer 2021; 12(8): 2285-2294. doi:10.7150/jca.53382
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP
Hongze Sun, Rangrang Wang, Yuan Liu, Haitao Mei, Xueni Liu, Zhihai Peng
J. Cancer 2021; 12(8): 2317-2325. doi:10.7150/jca.52158
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Secular trends in the incidence and survival of all leukemia types in the United States from 1975 to 2017
Xiaorong Yang, Hui Chen, Jinyu Man, Tongchao Zhang, Xiaolin Yin, Qiufeng He, Ming Lu
J. Cancer 2021; 12(8): 2326-2335. doi:10.7150/jca.52186
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-145 inhibition in gastric cancer
Hai-yan Piao, Shuai Guo, Haoyi Jin, Yue Wang, Jun Zhang
J. Cancer 2021; 12(8): 2336-2350. doi:10.7150/jca.49138
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Role of CT texture features for predicting outcome of pancreatic cancer patients with liver metastases
Junjie Hang, Kequn Xu, Ruohan Yin, Yueting Shao, Muhan Liu, Haifeng Shi, Xiaoyong Wang, Lixia Wu
J. Cancer 2021; 12(8): 2351-2358. doi:10.7150/jca.49569
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Classification of Clear Cell Renal Cell Carcinoma based on Tumor Suppressor Genomic Profiling
Weimin Zhong, Fengling Zhang, Chaoqun Huang, Yao Lin, Jiyi Huang
J. Cancer 2021; 12(8): 2359-2370. doi:10.7150/jca.50462
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification of a Prognostic Signature Model with Tumor Microenvironment for predicting Disease-free Survival after Radical Prostatectomy
Hao Zhao, Xuening Zhang, Zhan Shi, Bingxin Guo, Wenli Zhang, Kun He, Xueqi Hu, Songhe Shi
J. Cancer 2021; 12(8): 2371-2384. doi:10.7150/jca.51173
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Is cardia cancer a special type of gastric cancer? A differential analysis of early cardia cancer and non-cardia cancer
Liting Lv, Xiao Liang, Dan Wu, Feng Wang, Yan Zhang, Hui Cang, Xiongwei Deng, Mei Li
J. Cancer 2021; 12(8): 2385-2394. doi:10.7150/jca.51433
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prognostic Value of the Glasgow Prognostic Score on Overall Survival in patients with Advanced Non-Small Cell Lung Cancer
Mingmei Pan, Yun Zhao, Jianbo He, Huanqiong Wu, Yujia Pan, Qitao Yu, Shaozhang Zhou
J. Cancer 2021; 12(8): 2395-2402. doi:10.7150/jca.52215
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MRPL42 is activated by YY1 to promote lung adenocarcinoma progression
Wei Jiang, Chengpeng Zhang, Yunteng Kang, Xiaojun Yu, Pei Pang, Guangbin Li, Yu Feng
J. Cancer 2021; 12(8): 2403-2411. doi:10.7150/jca.52277
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression
Hangyu Zhang, Changgang Liu, Xinbo Wang, Yongfang Wang, Jie Zheng
J. Cancer 2021; 12(8): 2412-2421. doi:10.7150/jca.52426
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Msi1 inhibits cervical cancer cell apoptosis by downregulating BAK through AKT signaling
Xian Liu, Yanru Zhang, PengSheng Zheng, Nan Cui
J. Cancer 2021; 12(8): 2422-2429. doi:10.7150/jca.52950
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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CircNT5E promotes the proliferation and migration of bladder cancer via sponging miR-502-5p
Jinhui Yang, Xiaoyun Liu, Guangcheng Dai, Lanying Qu, Bo Tan, Bo Zhu, Fuming Qi, Xinyu Gai, Bo Cheng
J. Cancer 2021; 12(8): 2430-2439. doi:10.7150/jca.53385
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification of tumor mutation burden-related hub genes and the underlying mechanism in melanoma
Chuan Zhang, Dan Dang, Chenlu Liu, Yuqian Wang, Xianling Cong
J. Cancer 2021; 12(8): 2440-2449. doi:10.7150/jca.53697
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Impact of chemotherapy on lymphocytes and serological memory in recovered COVID-19 patients with acute leukemia
Wei Liu, Ziping Li, Wenjuan He, Dan Yu, Ping Wang, Li Cai, Peng Yang, Xuexing Chen, Xiaoping Zhang, Hao Zhou
J. Cancer 2021; 12(8): 2450-2455. doi:10.7150/jca.53863
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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YTHDF1 gene polymorphisms and neuroblastoma susceptibility in Chinese children: an eight-center case-control study
Jiabin Liu, Jiwen Cheng, Li Li, Yong Li, Haixia Zhou, Jiao Zhang, Suhong Li, Huimin Xia, Jing He, Zhonghua Yang
J. Cancer 2021; 12(8): 2465-2471. doi:10.7150/jca.54496
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Updated applications of Ultrasound in Uterine Cervical Cancer
Yi-Hsuan Hsiao, Shun-Fa Yang, Ya-Hui Chen, Tze-Ho Chen, Horng-Der Tsai, Ming-Chih Chou, Pang-Hsin Chou
J. Cancer 2021; 12(8): 2181-2189. doi:10.7150/jca.49479
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Management of early-stage breast cancer patients during the coronavirus disease 2019 (COVID-19) pandemic: The experience in China from a surgical standpoint
Wan Wang, Baoliang Guo, Chunguo Cui, Tong Sun, Shengnan Liu
J. Cancer 2021; 12(8): 2190-2198. doi:10.7150/jca.50501
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Updates of Pathogenesis, Diagnostic and Therapeutic Perspectives for Ovarian Clear Cell Carcinoma
Chenchen Zhu, Zhihao Xu, Tianjiao Zhang, Lili Qian, Weihua Xiao, Haiming Wei, Tengchuan Jin, Ying Zhou
J. Cancer 2021; 12(8): 2295-2316. doi:10.7150/jca.53395
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Insights into the role of ERp57 in cancer
Danyang Song, Hao Liu, Jian Wu, Xiaoliang Gao, Jianyu Hao, Daiming Fan
J. Cancer 2021; 12(8): 2456-2464. doi:10.7150/jca.48707
[Abstract] [Full text] [PDF] [PubMed] [PMC]