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Volume 15 (13); 2024

Research Papers

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Methylation of the Selected TP53 Introns in Advanced-Stage Ovarian Carcinomas
Wiktor Szewczuk, Oksana Szewczuk, Krzysztof Czajkowski, Robert Gromadka, Yan-Gao Man, Maciej Wałędziak, Andrzej Semczuk
J. Cancer 2024; 15(13): 4040-4046. doi:10.7150/jca.94945
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Glutathione and Xanthine Metabolic Changes in Tamoxifen Resistant Breast Cancer Cell Lines are Mediated by Down-Regulation of GSS and XDH and Correlated to Poor Prognosis
Mohammad Alwahsh, Yazan Hamadneh, Rosemarie Marchan, Lina A. Dahabiyeh, Ala A Alhusban, Aya Hasan, Jawad Alrawabdeh, Roland Hergenröder, Lama Hamadneh
J. Cancer 2024; 15(13): 4047-4058. doi:10.7150/jca.96659
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Unlocking the Potential of Ultra-High Dose Fractionated Radiation for Effective Treatment of Glioblastoma in Mice
Xiao-Yan Lan, Lukasz Kalkowski, Cheng-Yan Chu, Anna Jablonska, Shen Li, Mihoko Kai, Yue Gao, Miroslaw Janowski, Piotr Walczak
J. Cancer 2024; 15(13): 4060-4071. doi:10.7150/jca.95148
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GNL3L exhibits pro-tumor activities via NF-κB pathway as a poor prognostic factor in acute myeloid leukemia
Ji Li, Zhimin Wu, Yipeng Pan, Yi Chen, Junfeng Chu, Yun Cong, Qingliang Fang
J. Cancer 2024; 15(13): 4072-4080. doi:10.7150/jca.95339
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Acting mechanism and clinical significance of hsa_circ_0005927 in the invasion and metastasis of gastric cancer
Yongfu Shao, Xuan Yu, Meng Hu, Jianing Yan, Min Miao, Guoliang Ye, Junming Guo
J. Cancer 2024; 15(13): 4081-4094. doi:10.7150/jca.96749
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Pro-oncogene FBI-1 inhibits the ferroptosis of prostate carcinoma PC-3 cells via the microRNA-324-3p/GPX4 axis
Mingsheng Liu, Chenxiang Xu, Hua Yang, Qiyu Jiang, Guanyu Chen, Wei Wang, Tao Shao, Tibin Deng, Fei Yuan, Pingbo Xie, Hongqing Zhou
J. Cancer 2024; 15(13): 4097-4112. doi:10.7150/jca.96306
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TARDBP is a candidate diagnostic biomarker promoting tumor progression via impacting tumor immunity and tumor microenvironment
Min-Yi Luo, Zhe Han, Jiaqi Wang, Cheng Zhong, Jiancong Chen
J. Cancer 2024; 15(13): 4113-4127. doi:10.7150/jca.96800
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REEP4 as Potential Biomarker Associated with Predictive Prognosis and Immune Response in Kidney Clear Cell Carcinoma
Zixuan Chen, Xing Jia, Min Liu
J. Cancer 2024; 15(13): 4143-4155. doi:10.7150/jca.96135
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ECT2 promotes the occurrence and is a prognostic biomarker of head and neck squamous cell carcinoma
Shixiong Peng, Jinhang Wang, Naiheng Hei, Zifeng Cui
J. Cancer 2024; 15(13): 4156-4174. doi:10.7150/jca.95515
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Metabolic Heterogeneity of Tumor Cells and its Impact on Colon Cancer Metastasis: Insights from Single-Cell and Bulk Transcriptome Analyses
Yiwen Jia, Guangming Feng, Siyuan Chen, Wenhao Li, Zeguo Jia, Jian Wang, Hongxia Li, Shaocheng Hong, Fu Dai
J. Cancer 2024; 15(13): 4175-4196. doi:10.7150/jca.94630
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Impact of the number of lymph node dissections and a novel risk stratification on the prognosis in elderly locally advanced esophageal adenocarcinoma
Yahua Wu, Weiwei Gu, Bin Du, Chengliu Lv, Na Yao, Yingjiao Zhu, Jingxiang Ouyang, Jinhuo Lai
J. Cancer 2024; 15(13): 4197-4204. doi:10.7150/jca.96574
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Differences in Genomic Alterations and Accumulations of Heavy Metals Between Advanced Non-small Cell Lung Cancer Patients with and without Bone Metastasis
Zhong-Qiang Yao, Hui-Hui Jiang, Fei-Fei Wang, Zhi-Gang Fan, Yi-Ge Zhang, Shang-Dong Mou, Xia Cao, Cheng-Tian Li, Li-Sha Jiang, Li Song, Shu-Shen Ji, Qing-Juan Chen
J. Cancer 2024; 15(13): 4205-4218. doi:10.7150/jca.95191
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Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study
Jingyi Tang, Shengke Zhang, Lai Jiang, Jie Liu, Jiayu Xu, Chenglu Jiang, Zipei Chen, Xuancheng Zhou, Claire Fuller, Jinbang Huang, Haiqing Chen, Guanhu Yang, Changsong Bai, Defeng Yin, Bo Li, Hao Chi
J. Cancer 2024; 15(13): 4219-4231. doi:10.7150/jca.96744
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Derived from fangchinoline, LYY-35 exhibits an inhibiting effect on human NSCLC cancer A549 cells
Bo Wang, Shan Long, Junjie Lan, Kaixiong Luo, Wangming Zhang, Xiaosong Li, Weidong Pan, Jielin Liu
J. Cancer 2024; 15(13): 4232-4243. doi:10.7150/jca.96582
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Elevated RACGAP1 Expression Enhances Malignant Potential in Lung Adenocarcinoma and Serves as a Prognostic Factor
Wei Lai, Yunshu Su, Yangbo Li, Yifan Zuo, Kunzhuo He, Tianyu Zhang, Dunyu Peng, Wei Wang
J. Cancer 2024; 15(13): 4244-4258. doi:10.7150/jca.96334
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Tanreqing injection inhibits stemness and enhances sensitivity of non-small cell lung cancer models to gefitinib through ROS/STAT3 signaling pathway
Zhenzhen Xiao, Lina Ding, Yaya Yu, Changju Ma, Chenjing Lei, Yihong Liu, Xuesong Chang, Yadong Chen, Yihan He, Yanjuan Zhu, Haibo Zhang
J. Cancer 2024; 15(13): 4259-4274. doi:10.7150/jca.94438
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Enhanced Multimodal Brain Tumor Classification in MR Images using 2D ResNet as backbone with Explicit Tumor Size Information
Yunhao Zeng, Nianbo Liu, Xinduoji Yang, Chenke Huang, Ming Liu
J. Cancer 2024; 15(13): 4275-4286. doi:10.7150/jca.95987
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Prognostic signature and immune efficacy of m1A-, m5C-, m6A-, m7G-, and DNA methylation-related regulators in hepatocellular carcinoma
Donghong Liu, Xinyu Zhou, Jun Zhao
J. Cancer 2024; 15(13): 4287-4300. doi:10.7150/jca.95730
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SIVA-1 interaction with PCBP1 serves as a predictive biomarker for cisplatin sensitivity in gastric cancer and its inhibitory effect on tumor growth in vivo
Fan-Biao Kong, Zheng-Yi Shi, Yu-Liang Huang, Huan-Huan Chen, Qiao-Ming Deng, Kun Wu, Zhou Zhu, Lei Li, Sheng Xu, Xiao-Gang Zhong, Jian-Rong Yang, Xiao-Tong Wang
J. Cancer 2024; 15(13): 4301-4312. doi:10.7150/jca.92963
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Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells
Peiyao Gao, Amin Chen, Hengjin Tian, Feifan Wang, Na Wang, Kunpeng Ge, Chaoqun Lian, Fengchao Wang, Qiang Zhang
J. Cancer 2024; 15(13): 4313-4327. doi:10.7150/jca.92745
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Atractylenolide II combined with Interferon-γ synergistically ameliorates colorectal cancer progression in vivo and in vitro by blocking the NF-kB p65/PD-L1 pathway
Yangsheng Wu, Shijie Dai, YuJia Zhang, Zheming Li, Bo Zhu, Qingsheng Liu, Like Wo, Zhiling Yu, Xiaofeng Yuan, Xiaobing Dou
J. Cancer 2024; 15(13): 4328-4344. doi:10.7150/jca.96647
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Establishment and Application of Novel Hypoxia-driven Dual-reporter Model to Investigate Hypoxic Impact on Radiation Sensitivity in Human Nasopharyngeal Carcinoma Xenografts
Jun Dong, Chengtao Wang, Tian Zhang, Xiaobi Yu, Haihua Peng, Zhenhua Xiao, Zhenyu Wang, Bixiu Wen
J. Cancer 2024; 15(13): 4345-4359. doi:10.7150/jca.96378
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MYBL2 is a Novel Independent Prognostic Biomarker and Correlated with TMB in pancreatic cancer
Yanping Li, Shanshan Wang, Miao Guo, Rui Yang, Xiaonan Wei, Haibin Li, Siyuan Yan
J. Cancer 2024; 15(13): 4360-4373. doi:10.7150/jca.96320
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Tripartite motif-containing 28 (TRIM28) expression and cordycepin inhibition in progression, prognosis, and therapeutics of patients with breast invasive carcinoma
Dabing Li, Jingliang Cheng, Wenqian Zhang, Lianmei Zhang, Mazaher Maghsoudloo, Jiewen Fu, Xiaoyan Liu, Xiuli Xiao, Chunli Wei, Junjiang Fu
J. Cancer 2024; 15(13): 4374-4385. doi:10.7150/jca.95876
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Multidimensional analysis of TMEM132A in pan-cancer: unveiling its potential as a biomarker for treatment response prediction
Mingyue Zhang, Shengli Wang, Meihong He, Zhanpeng Zhang, Jie Wu, Hongyan Sun, Hua Zhang, Hengwen Yang
J. Cancer 2024; 15(13): 4386-4405. doi:10.7150/jca.96396
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Treatment of HNSC and pulmonary metastasis using the anti-helminthic drug niclosamide to modulate Stat3 signaling activity
Wanjin Jiang, Xiaonan Yang, Xiao Han, Ruijia Gan, Hongting Hua, Dongyu Si, Fuqin Sun, Zhimin Ding, Xinbei Zhu, Qi Yang, Huabing Zhang, Chaobing Gao
J. Cancer 2024; 15(13): 4406-4416. doi:10.7150/jca.95682
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TRIM28 Regulates Proliferation of Gastric Cancer Cells Partly Through SRF/IDO1 Axis
Zhiye Huang, Jiaxing Dong, Taohua Guo, Wanju Jiang, Renhao Hu, Shun Zhang, Tao Du, Xiaohua Jiang
J. Cancer 2024; 15(13): 4417-4429. doi:10.7150/jca.95094
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Reversal of Platinum-based Chemotherapy Resistance in Ovarian Cancer by Naringin Through Modulation of The Gut Microbiota in a Humanized Nude Mouse Model
Bingqing Xie, Xiaoni Zhou, Chuanlin Luo, Yilin Fang, Yufei Wang, Jing Wei, Liping Cai, Tingtao Chen
J. Cancer 2024; 15(13): 4430-4447. doi:10.7150/jca.96448
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Review

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Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements
Subhrojyoti Ghosh, Atharva Anand Mahajan, Anuvab Dey, Ramya Lakshmi Rajendran, Ankita Chowdhury, Sushmita Sen, Subhobrata Paul, Sourav Majhi, Chae Moon Hong, Prakash Gangadaran, Byeong-Cheol Ahn, Anand Krishnan
J. Cancer 2024; 15(13): 4128-4142. doi:10.7150/jca.95709
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Erratum

Ophiopogonin-B Suppresses Epithelial-mesenchymal Transition in Human Lung Adenocarcinoma Cells via the Linc00668/miR-432-5p/EMT Axis: Erratum
Cheng Hu, Rilei Jiang, Ziyu Cheng, Yueyang Lu, Ling Gu, Hongxiao Li, Liqiu Li, Qian Gao, Meijuan Chen, Xu Zhang
J. Cancer 2024; 15(13): 4095-4096. doi:10.7150/jca.98604
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