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Volume 15 (13); 2024

Research Papers

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Methylation of the Selected TP53 Introns in Advanced-Stage Ovarian Carcinomas Wiktor Szewczuk, Oksana Szewczuk, Krzysztof Czajkowski, Robert Gromadka, Yan-Gao Man, Maciej Wałędziak, Andrzej Semczuk J. Cancer 2024; 15(13): 4040-4046. doi:10.7150/jca.94945 Full text PDF PubMed PMC


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Glutathione and Xanthine Metabolic Changes in Tamoxifen Resistant Breast Cancer Cell Lines are Mediated by Down-Regulation of GSS and XDH and Correlated to Poor Prognosis Mohammad Alwahsh, Yazan Hamadneh, Rosemarie Marchan, Lina A. Dahabiyeh, Ala A Alhusban, Aya Hasan, Jawad Alrawabdeh, Roland Hergenröder, Lama Hamadneh J. Cancer 2024; 15(13): 4047-4058. doi:10.7150/jca.96659 Full text PDF PubMed PMC


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Unlocking the Potential of Ultra-High Dose Fractionated Radiation for Effective Treatment of Glioblastoma in Mice Xiao-Yan Lan, Lukasz Kalkowski, Cheng-Yan Chu, Anna Jablonska, Shen Li, Mihoko Kai, Yue Gao, Miroslaw Janowski, Piotr Walczak J. Cancer 2024; 15(13): 4060-4071. doi:10.7150/jca.95148 Full text PDF PubMed PMC


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GNL3L exhibits pro-tumor activities via NF-κB pathway as a poor prognostic factor in acute myeloid leukemia Ji Li, Zhimin Wu, Yipeng Pan, Yi Chen, Junfeng Chu, Yun Cong, Qingliang Fang J. Cancer 2024; 15(13): 4072-4080. doi:10.7150/jca.95339 Full text PDF PubMed PMC


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Acting mechanism and clinical significance of hsa_circ_0005927 in the invasion and metastasis of gastric cancer Yongfu Shao, Xuan Yu, Meng Hu, Jianing Yan, Min Miao, Guoliang Ye, Junming Guo J. Cancer 2024; 15(13): 4081-4094. doi:10.7150/jca.96749 Full text PDF PubMed PMC


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Pro-oncogene FBI-1 inhibits the ferroptosis of prostate carcinoma PC-3 cells via the microRNA-324-3p/GPX4 axis Mingsheng Liu, Chenxiang Xu, Hua Yang, Qiyu Jiang, Guanyu Chen, Wei Wang, Tao Shao, Tibin Deng, Fei Yuan, Pingbo Xie, Hongqing Zhou J. Cancer 2024; 15(13): 4097-4112. doi:10.7150/jca.96306 Full text PDF PubMed PMC


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TARDBP is a candidate diagnostic biomarker promoting tumor progression via impacting tumor immunity and tumor microenvironment Min-Yi Luo, Zhe Han, Jiaqi Wang, Cheng Zhong, Jiancong Chen J. Cancer 2024; 15(13): 4113-4127. doi:10.7150/jca.96800 Full text PDF PubMed PMC


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REEP4 as Potential Biomarker Associated with Predictive Prognosis and Immune Response in Kidney Clear Cell Carcinoma Zixuan Chen, Xing Jia, Min Liu J. Cancer 2024; 15(13): 4143-4155. doi:10.7150/jca.96135 Full text PDF PubMed PMC


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ECT2 promotes the occurrence and is a prognostic biomarker of head and neck squamous cell carcinoma Shixiong Peng, Jinhang Wang, Naiheng Hei, Zifeng Cui J. Cancer 2024; 15(13): 4156-4174. doi:10.7150/jca.95515 Full text PDF PubMed PMC


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Metabolic Heterogeneity of Tumor Cells and its Impact on Colon Cancer Metastasis: Insights from Single-Cell and Bulk Transcriptome Analyses Yiwen Jia, Guangming Feng, Siyuan Chen, Wenhao Li, Zeguo Jia, Jian Wang, Hongxia Li, Shaocheng Hong, Fu Dai J. Cancer 2024; 15(13): 4175-4196. doi:10.7150/jca.94630 Full text PDF PubMed PMC


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Impact of the number of lymph node dissections and a novel risk stratification on the prognosis in elderly locally advanced esophageal adenocarcinoma Yahua Wu, Weiwei Gu, Bin Du, Chengliu Lv, Na Yao, Yingjiao Zhu, Jingxiang Ouyang, Jinhuo Lai J. Cancer 2024; 15(13): 4197-4204. doi:10.7150/jca.96574 Full text PDF PubMed PMC


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Differences in Genomic Alterations and Accumulations of Heavy Metals Between Advanced Non-small Cell Lung Cancer Patients with and without Bone Metastasis Zhong-Qiang Yao, Hui-Hui Jiang, Fei-Fei Wang, Zhi-Gang Fan, Yi-Ge Zhang, Shang-Dong Mou, Xia Cao, Cheng-Tian Li, Li-Sha Jiang, Li Song, Shu-Shen Ji, Qing-Juan Chen J. Cancer 2024; 15(13): 4205-4218. doi:10.7150/jca.95191 Full text PDF PubMed PMC


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Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study Jingyi Tang, Shengke Zhang, Lai Jiang, Jie Liu, Jiayu Xu, Chenglu Jiang, Zipei Chen, Xuancheng Zhou, Claire Fuller, Jinbang Huang, Haiqing Chen, Guanhu Yang, Changsong Bai, Defeng Yin, Bo Li, Hao Chi J. Cancer 2024; 15(13): 4219-4231. doi:10.7150/jca.96744 Full text PDF PubMed PMC


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Derived from fangchinoline, LYY-35 exhibits an inhibiting effect on human NSCLC cancer A549 cells Bo Wang, Shan Long, Junjie Lan, Kaixiong Luo, Wangming Zhang, Xiaosong Li, Weidong Pan, Jielin Liu J. Cancer 2024; 15(13): 4232-4243. doi:10.7150/jca.96582 Full text PDF PubMed PMC


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Elevated RACGAP1 Expression Enhances Malignant Potential in Lung Adenocarcinoma and Serves as a Prognostic Factor Wei Lai, Yunshu Su, Yangbo Li, Yifan Zuo, Kunzhuo He, Tianyu Zhang, Dunyu Peng, Wei Wang J. Cancer 2024; 15(13): 4244-4258. doi:10.7150/jca.96334 Full text PDF PubMed PMC


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Tanreqing injection inhibits stemness and enhances sensitivity of non-small cell lung cancer models to gefitinib through ROS/STAT3 signaling pathway Zhenzhen Xiao, Lina Ding, Yaya Yu, Changju Ma, Chenjing Lei, Yihong Liu, Xuesong Chang, Yadong Chen, Yihan He, Yanjuan Zhu, Haibo Zhang J. Cancer 2024; 15(13): 4259-4274. doi:10.7150/jca.94438 Full text PDF PubMed PMC


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Enhanced Multimodal Brain Tumor Classification in MR Images using 2D ResNet as backbone with Explicit Tumor Size Information Yunhao Zeng, Nianbo Liu, Xinduoji Yang, Chenke Huang, Ming Liu J. Cancer 2024; 15(13): 4275-4286. doi:10.7150/jca.95987 Full text PDF PubMed PMC


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Prognostic signature and immune efficacy of m1A-, m5C-, m6A-, m7G-, and DNA methylation-related regulators in hepatocellular carcinoma Donghong Liu, Xinyu Zhou, Jun Zhao J. Cancer 2024; 15(13): 4287-4300. doi:10.7150/jca.95730 Full text PDF PubMed PMC


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SIVA-1 interaction with PCBP1 serves as a predictive biomarker for cisplatin sensitivity in gastric cancer and its inhibitory effect on tumor growth in vivo Fan-Biao Kong, Zheng-Yi Shi, Yu-Liang Huang, Huan-Huan Chen, Qiao-Ming Deng, Kun Wu, Zhou Zhu, Lei Li, Sheng Xu, Xiao-Gang Zhong, Jian-Rong Yang, Xiao-Tong Wang J. Cancer 2024; 15(13): 4301-4312. doi:10.7150/jca.92963 Full text PDF PubMed PMC


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Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells Peiyao Gao, Amin Chen, Hengjin Tian, Feifan Wang, Na Wang, Kunpeng Ge, Chaoqun Lian, Fengchao Wang, Qiang Zhang J. Cancer 2024; 15(13): 4313-4327. doi:10.7150/jca.92745 Full text PDF PubMed PMC


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Atractylenolide II combined with Interferon-γ synergistically ameliorates colorectal cancer progression in vivo and in vitro by blocking the NF-kB p65/PD-L1 pathway Yangsheng Wu, Shijie Dai, YuJia Zhang, Zheming Li, Bo Zhu, Qingsheng Liu, Like Wo, Zhiling Yu, Xiaofeng Yuan, Xiaobing Dou J. Cancer 2024; 15(13): 4328-4344. doi:10.7150/jca.96647 Full text PDF PubMed PMC


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Establishment and Application of Novel Hypoxia-driven Dual-reporter Model to Investigate Hypoxic Impact on Radiation Sensitivity in Human Nasopharyngeal Carcinoma Xenografts Jun Dong, Chengtao Wang, Tian Zhang, Xiaobi Yu, Haihua Peng, Zhenhua Xiao, Zhenyu Wang, Bixiu Wen J. Cancer 2024; 15(13): 4345-4359. doi:10.7150/jca.96378 Full text PDF PubMed PMC


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MYBL2 is a Novel Independent Prognostic Biomarker and Correlated with TMB in pancreatic cancer Yanping Li, Shanshan Wang, Miao Guo, Rui Yang, Xiaonan Wei, Haibin Li, Siyuan Yan J. Cancer 2024; 15(13): 4360-4373. doi:10.7150/jca.96320 Full text PDF PubMed PMC


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Tripartite motif-containing 28 (TRIM28) expression and cordycepin inhibition in progression, prognosis, and therapeutics of patients with breast invasive carcinoma Dabing Li, Jingliang Cheng, Wenqian Zhang, Lianmei Zhang, Mazaher Maghsoudloo, Jiewen Fu, Xiaoyan Liu, Xiuli Xiao, Chunli Wei, Junjiang Fu J. Cancer 2024; 15(13): 4374-4385. doi:10.7150/jca.95876 Full text PDF PubMed PMC


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Multidimensional analysis of TMEM132A in pan-cancer: unveiling its potential as a biomarker for treatment response prediction Mingyue Zhang, Shengli Wang, Meihong He, Zhanpeng Zhang, Jie Wu, Hongyan Sun, Hua Zhang, Hengwen Yang J. Cancer 2024; 15(13): 4386-4405. doi:10.7150/jca.96396 Full text PDF PubMed PMC


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Treatment of HNSC and pulmonary metastasis using the anti-helminthic drug niclosamide to modulate Stat3 signaling activity Wanjin Jiang, Xiaonan Yang, Xiao Han, Ruijia Gan, Hongting Hua, Dongyu Si, Fuqin Sun, Zhimin Ding, Xinbei Zhu, Qi Yang, Huabing Zhang, Chaobing Gao J. Cancer 2024; 15(13): 4406-4416. doi:10.7150/jca.95682 Full text PDF PubMed PMC


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TRIM28 Regulates Proliferation of Gastric Cancer Cells Partly Through SRF/IDO1 Axis Zhiye Huang, Jiaxing Dong, Taohua Guo, Wanju Jiang, Renhao Hu, Shun Zhang, Tao Du, Xiaohua Jiang J. Cancer 2024; 15(13): 4417-4429. doi:10.7150/jca.95094 Full text PDF PubMed PMC


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Reversal of Platinum-based Chemotherapy Resistance in Ovarian Cancer by Naringin Through Modulation of The Gut Microbiota in a Humanized Nude Mouse Model Bingqing Xie, Xiaoni Zhou, Chuanlin Luo, Yilin Fang, Yufei Wang, Jing Wei, Liping Cai, Tingtao Chen J. Cancer 2024; 15(13): 4430-4447. doi:10.7150/jca.96448 Full text PDF PubMed PMC

Review

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Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements Subhrojyoti Ghosh, Atharva Anand Mahajan, Anuvab Dey, Ramya Lakshmi Rajendran, Ankita Chowdhury, Sushmita Sen, Subhobrata Paul, Sourav Majhi, Chae Moon Hong, Prakash Gangadaran, Byeong-Cheol Ahn, Anand Krishnan J. Cancer 2024; 15(13): 4128-4142. doi:10.7150/jca.95709 Full text PDF PubMed PMC

Erratum

Ophiopogonin-B Suppresses Epithelial-mesenchymal Transition in Human Lung Adenocarcinoma Cells via the Linc00668/miR-432-5p/EMT Axis: Erratum Cheng Hu, Rilei Jiang, Ziyu Cheng, Yueyang Lu, Ling Gu, Hongxiao Li, Liqiu Li, Qian Gao, Meijuan Chen, Xu Zhang J. Cancer 2024; 15(13): 4095-4096. doi:10.7150/jca.98604 Full text PDF PubMed PMC

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