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Volume 16 (1); 2025

Research Papers

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Pharmacological Profiling of Calotropis Procera and Rhazya Stricta: Unraveling the Antibacterial and Anti-Cancer Potential of Chemically Active Metabolites
Sahar S. Alghamdi, Allulu Y. Alturki, Rizwan Ali, Rasha S. Suliman, Afrah E. Mohammed, Atheer Al Dairem, Zeyad I. Alehaideb, Raghad A. Alshafi, Sara A. Alghashem, Ishrat Rahman
J. Cancer 2025; 16(1): 1-21. doi:10.7150/jca.96848
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Causal inference between immune cells and glioblastoma: a bidirectional Mendelian randomization study
Shiqiang Hou, Chunjing Jin, Beitian Shi, Yinan Chen, Ning Lin
J. Cancer 2025; 16(1): 22-32. doi:10.7150/jca.100519
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Raddeanin A (RA) Inhibited EMT and Stemness in Glioblastoma via downregulating Skp2
Weiqiang Jia, Yanling Zhang, Qiang Zhao, Min Gong, Yang Cao, Jia Liu, Shuang Luo
J. Cancer 2025; 16(1): 44-54. doi:10.7150/jca.95266
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MiR-675 Inhibits Primary Ovarian Tumor Growth and Metastasis by Suppressing EMT and TGFβ Signaling
Xinxin Zhao, Ziping Liu, Yongshuai Li, Shiji Song, Baojin Wang, Lawrence M. Pfeffer, Wenjing Zhang, Junming Yue
J. Cancer 2025; 16(1): 55-65. doi:10.7150/jca.102654
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Exploring the Role of Thioredoxin system in Cancer Immunotherapy
Lin Sun, Anni Yu, Yang Yang, Zhiruo Wang, Wenqian Wang, Lan Luo
J. Cancer 2025; 16(1): 66-80. doi:10.7150/jca.98306
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Identification of the oncogenic role and clinical implication of LZTS3 in Colon Adenocarcinoma
Kui Ye, Huaxiang Cao, Zihao Xu, Peng Liu, Xueying Jiang, Qiancheng Liu, Hongquan Yang, Menghua Huo, Teng Wang, Jian Wang
J. Cancer 2025; 16(1): 81-91. doi:10.7150/jca.102204
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Screening of Hub Genes and Therapeutic Drugs in Cervical Cancer Using Integrated Bioinformatics Analysis
Ziruo Talihati, Kayisaier Abudurousuli, Sendaer Hailati, Mengyuan Han, Muhadaisi Nuer, Nawaz Khan, Nulibiya Maihemuti, Jimilihan Simayi, Weiyi Zhang, Wenting Zhou
J. Cancer 2025; 16(1): 92-109. doi:10.7150/jca.87027
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Targeting the BMI1-Noxa axis by Dioscin induces apoptosis in oral squamous cell carcinoma cells
Jinglin Fang, Ruirui Wang, Xiaoying Li, XiaoCong Wang, Lingling Gong, An Lou, Jie Lu, Xiaoyue Zhang, Qin Zhao, Xinfang Yu, Qiling Zhou, Ming Li
J. Cancer 2025; 16(1): 110-121. doi:10.7150/jca.100631
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Pan-cancer analyses reveal cancer-type-specific autophagy signatures with potential implications for prognosis and therapy response
Hongyan Yuan, Xiaojing Zhu, Jiaxing Zhang, Zixin Zhang, Weihua Li, Jiankai Xu
J. Cancer 2025; 16(1): 122-134. doi:10.7150/jca.101046
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The effect of intraoperative radiotherapy in musculoskeletal malignancy: A population study from US SEER database
Yao Xu, Zhe Feng, YongHeng Liu, JinYan Feng, Yan Zhang, Chao Zhang, XiuXin Han, LiMing Xu, GuoWen Wang
J. Cancer 2025; 16(1): 135-145. doi:10.7150/jca.100678
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Impact of ALDH1A1 Expression in Intrahepatic Cholangiocellular Carcinoma
Konrad Kurowski, Melanie Föll, Tilman Werner, Oliver Schilling, Martin Werner, Stefan Fichtner-Feigl, Bertram Bengsch, Peter Bronsert, Philipp Anton Holzner, Sylvia Timme
J. Cancer 2025; 16(1): 171-182. doi:10.7150/jca.99944
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Deciphering the Prognostic Landscape of Esophageal Adenocarcinoma: A PANoptosis-Related Gene Signature
Haijing Fu, Mengyan Liu, Huiyu Li, Li Yu, Haizhu Song, Xiaoyuan Chu, Wei Bao
J. Cancer 2025; 16(1): 183-200. doi:10.7150/jca.102180
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Unveiling the Prognostic Power and Immune Landscape of MyD88 in Breast Cancer: an Integrative Bioinformatics and IHC Approach
Xin Yu, Qinfang Zhang, Bei Li, Shengrong Sun, Juanjuan Li, Wenge Li
J. Cancer 2025; 16(1): 201-213. doi:10.7150/jca.103403
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Knockdown of HOXD13 in Oral Squamous Cell Carcinoma Inhibited its Proliferation, Migration, and Influenced Fatty Acid Metabolism
Xingyue Ma, Xiao Zhang, Haiyang Li, Shuang Mei, Bowen Wang, Shuai Guan, Yitong Wang, Yuantao Li, Siyi Li, Xiangjun Li
J. Cancer 2025; 16(1): 214-226. doi:10.7150/jca.102100
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Demethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
Lina Wang, Wei Zhou, Wenxi Wang, Yuxin Liang, Qiqi Xue, Zhen Zhang, Jinghe Yuan, Xiaohong Fang
J. Cancer 2025; 16(1): 227-240. doi:10.7150/jca.92797
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Metabolomics-based combination of GH and NVB in the treatment of NSCLC lung cancer recurrence
Xinxin Li, Fengfei Chen, Rui Yang, Zhaohui Song, Xiaohui Ma, Li Sun, Shengtao Yuan
J. Cancer 2025; 16(1): 265-278. doi:10.7150/jca.102722
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Analysis of the short-term efficacy of 2 versus 3 cycles of neoadjuvant immunotherapy combined with chemotherapy in patients with esophageal squamous cell carcinoma
Yi Gan, Ting Bao, Zhiwei Tang, Chao Cheng, Haoshuai Zhu
J. Cancer 2025; 16(1): 279-287. doi:10.7150/jca.102215
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The cellular signaling crosstalk between memory B cells and tumor cells in nasopharyngeal carcinoma cannot be overlooked: Their involvement in tumor progression and treatment strategy is significant
Haiyu Li, Yanjie Bian, Zhikai Xiahou, Zhijie Zhao, Fu Zhao, Qinghan Zhang
J. Cancer 2025; 16(1): 288-314. doi:10.7150/jca.101420
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WTAP regulates Mitochondrial damage and Lipid oxidation in HCC by NOA1 mediated m6A modification
Sheng Liu, Mei Shang, Jiao Gong, Hengchang Sun, Bo Hu
J. Cancer 2025; 16(1): 315-330. doi:10.7150/jca.102618
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The causal association between neutrophil counts and the risk of lung cancer: a Mendelian randomization study
Yunzhao Ren, Zhaojun Lu, Xiaoxue Liu
J. Cancer 2025; 16(1): 331-338. doi:10.7150/jca.100884
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Comprehensive analysis of genomic alterations and novel prognostic biomarkers, and establishment of prediction models of metastasis in metastatic non-small cell lung cancer
Kangwei Wang, Meifeng Ye, Zexun Mo, Xiaomei Huang, Yujun Li, Shuquan Wei
J. Cancer 2025; 16(1): 339-350. doi:10.7150/jca.97070
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SIGLEC1 as a novel prognostic factor is regulated by Yiqi Huayu Jiedu Decoction in colorectal cancer
Yejin Zhu, Xinping Wang, Qianyi Wang, Shanfan Shi, Jun He, Chao Jiang
J. Cancer 2025; 16(1): 351-367. doi:10.7150/jca.99278
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Reviews

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Technical and Biological Biases in Bulk Transcriptomic Data Mining for Cancer Research
Hengrui Liu, Yiying Li, Miray Karsidag, Tiffany Tu, Panpan Wang
J. Cancer 2025; 16(1): 33-43. doi:10.7150/jca.100922
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Insights into Structure and Function of Growth Arrest Specific 2 (GAS2)
Wenjuan Ma, Jiawei Lin, Rongyao Ma, Yang Bai, Di Wu, Xiuyan Zhang, Haixia Zhou, Yun Zhao, Lei Zhang
J. Cancer 2025; 16(1): 146-156. doi:10.7150/jca.102893
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The Role of AIM2 in Cancer Development: Inflammasomes and Beyond
Lina Sui, Yuling Xi, Siping Zheng, Qiuxiang Xiao, Zhiping Liu
J. Cancer 2025; 16(1): 157-170. doi:10.7150/jca.101473
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New Horizons of Biomarkers in Metastatic Thyroid Cancer
Alicia Sanchez Cendra, Leonel Pekarek, Beatriz Iglesias Pedrejón, Loreto Bernier, Eduardo David Roberts Cervantes, Cristina Sanchez Cendra, Javier Cassinello, Laura López-Gonzalez, Félix Mañez, Concepción Blanco Carrero, Clara Tasende Fernández, Tomás Ratia Giménez, Diego Martín Córdova García, Alberto Gutiérrez-Calvo, Melchor Álvarez-Mon, Raúl Díaz-Pedrero, Miguel A Ortega
J. Cancer 2025; 16(1): 241-264. doi:10.7150/jca.101395
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