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Volume 11 (5); 2020

Research Papers

Development and validation of a robust multigene signature as an aid to predict early relapse in stage I-III clear cell and papillary renal cell cancer
Da-Long Cao, Wei-Xing Dai, Yong-Qiang Huang, Lei-Jun Yu, Jun-Long Wu, Guo-Hai Shi, Hai-Liang Zhang, Yao Zhu, Bo Dai, Ding-Wei Ye
J. Cancer 2020; 11(5): 997-1007. doi:10.7150/jca.38274
Abstract Full text PDF PubMed PMC

Late results of a randomized trial on the role of mild hypofractionated radiotherapy for the treatment of localized prostate cancer
Petros Alexidis, Sotirios Karatzoglou, Dimitris Dragoumis, Konstantinos Drevelegas, Ioannis Tzitzikas, Konstantinos Hatzimouratidis, Ioannis Chrisogonidis, Aris Ioannidis, Iason Nikolaos Katsios, Paul Zarogoulidis, Konstantinos Sapalidis, Charilaos Koulouris, Nikolaos Michalopoulos, Dimitrios Giannakidis, Zoi Aidoni, Varbara Fyntanidou, Aikaterini Amaniti, Konstantina Boniou, Isaak Kesisoglou, Anastasios Vagionas, Konstantinos Romanidis, Panagoula Oikonomou, Alexandru Marian Goganau, Savas Petanidis, Elena Maragouli, Christoforos Kosmidis
J. Cancer 2020; 11(5): 1008-1016. doi:10.7150/jca.37825
Abstract Full text PDF PubMed PMC

Target Therapy With Vaccinia Virus Harboring IL-24 For Human Breast Cancer
Lili Deng, Jun Fan, Yuedi Ding, Xue Yang, Biao Huang, Zhigang Hu
J. Cancer 2020; 11(5): 1017-1026. doi:10.7150/jca.37590
Abstract Full text PDF PubMed PMC

Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis
Hui Qiao, Xiao Tan, Dao-jun Lv, Rong-wei Xing, Fang-peng Shu, Chuan-fan Zhong, Chun Li, Ya-guang Zou, Xiang-ming Mao
J. Cancer 2020; 11(5): 1027-1037. doi:10.7150/jca.37401
Abstract Full text PDF PubMed PMC

The somatic mutation landscape of Chinese Colorectal Cancer
Rong Ma, Changwen Jing, Yuan Zhang, Haixia Cao, Siwen Liu, Zhuo Wang, Dan Chen, Junying Zhang, Yang Wu, Jianzhong Wu, Jifeng Feng
J. Cancer 2020; 11(5): 1038-1046. doi:10.7150/jca.37017
Abstract Full text PDF PubMed PMC

Risk of non-melanoma skin cancer in patients with psoriasis: An updated evidence from systematic review with meta-analysis
Xiujuan Wang, Qiang Liu, Lingling Wu, Zhenhua Nie, Zubing Mei
J. Cancer 2020; 11(5): 1047-1055. doi:10.7150/jca.37015
Abstract Full text PDF PubMed PMC

Thirty-year trends in clinicopathologic characteristics and prognosis after gastrectomy for gastric cancer: A single institution in Northern China
Yu-en Tan, Peng-liang Wang, Song-cheng Yin, Chao Zhang, Wen-bin Hou, Hui-mian Xu
J. Cancer 2020; 11(5): 1056-1062. doi:10.7150/jca.36927
Abstract Full text PDF PubMed PMC

Prognostic value of the serum apolipoprotein B to apolipoprotein A-I ratio in metastatic colorectal cancer patients
Dong-Dong Yang, Zhan-Hong Chen, De-Shen Wang, Hong-En Yu, Jia-Huan Lu, Rui-Hua Xu, Zhao-Lei Zeng
J. Cancer 2020; 11(5): 1063-1074. doi:10.7150/jca.35659
Abstract Full text PDF PubMed PMC

Systematic analyses of genetic variants in chromatin interaction regions identified four novel lung cancer susceptibility loci
Pei Ji, Dongsheng Ding, Na Qin, Cheng Wang, Meng Zhu, Yuancheng Li, Juncheng Dai, Guangfu Jin, Zhibin Hu, Hongbing Shen, Liang Chen, Hongxia Ma
J. Cancer 2020; 11(5): 1075-1081. doi:10.7150/jca.35127
Abstract Full text PDF PubMed PMC

Diagnostic accuracy of photodynamic diagnosis with 5-aminolevulinic acid, hexaminolevulinate and narrow band imaging for non-muscle invasive bladder cancer
Changhao Chen, Hao Huang, Yue Zhao, Hao Liu, Yuming Luo, Richard J. Sylvester, Jia ping Li, Thomas B. Lam, Tianxin Lin, Jian Huang
J. Cancer 2020; 11(5): 1082-1093. doi:10.7150/jca.34527
Abstract Full text PDF PubMed PMC

Androgen Receptor (AR)-TLR4 Crosstalk Mediates Gender Disparities in Hepatocellular Carcinoma Incidence and Progression
Qiuju Han, Dan Yang, Chunlai Yin, Jian Zhang
J. Cancer 2020; 11(5): 1094-1103. doi:10.7150/jca.30682
Abstract Full text PDF PubMed PMC

Comparison of different images in gross target volume delineating on VX2 nasopharyngeal transplantation tumor models
Zhang-Qiang Xiang, Saber Imani, Yue Hu, Rui-Lin Ding, Hao-Wen Pang, Yue Chen, Shao-Zhi Fu, Fang Xie, Wen-Feng He, Qing-Lian Wen
J. Cancer 2020; 11(5): 1104-1114. doi:10.7150/jca.36076
Abstract Full text PDF PubMed PMC

Dihydroartemisinin suppresses bladder cancer cell invasion and migration by regulating KDM3A and p21
Tao Wang, Rongtuan Luo, Wei Li, Houyu Yan, Shunqiang Xie, Wen Xiao, Yongfeng Wang, Bin Chen, Peide Bai, Jinchun Xing
J. Cancer 2020; 11(5): 1115-1124. doi:10.7150/jca.36174
Abstract Full text PDF PubMed PMC

Expression of MMP-14 and prognosis in digestive system carcinoma: a meta-analysis and databases validation
Fujiao Duan, Zhen Peng, Jingjing Yin, Zhongyu Yang, Jia Shang
J. Cancer 2020; 11(5): 1141-1150. doi:10.7150/jca.36469
Abstract Full text PDF PubMed PMC

Overexpression of PPT2 Represses the Clear Cell Renal Cell Carcinoma Progression by Reducing Epithelial-to-mesenchymal Transition
ChangFei Yuan, ZhiYong Xiong, Jian Shi, JingTao Peng, XianGui Meng, Cheng Wang, WenJun Hu, ZeYuan Ru, KaiRu Xie, HongMei Yang, Ke Chen, XiaoPing Zhang
J. Cancer 2020; 11(5): 1151-1161. doi:10.7150/jca.36477
Abstract Full text PDF PubMed PMC

Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features
Yi Mei, Dongyan Cai, Xiaofeng Dai
J. Cancer 2020; 11(5): 1162-1169. doi:10.7150/jca.37117
Abstract Full text PDF PubMed PMC

Up-regulation of peroxiredoxin-1 promotes cell proliferation and metastasis and inhibits apoptosis in cervical cancer
Ermei Lu, Xiaoli Hu, Chunyu Pan, Jingjing Chen, Yichi Xu, Xueqiong Zhu
J. Cancer 2020; 11(5): 1170-1181. doi:10.7150/jca.37147
Abstract Full text PDF PubMed PMC

Enhanced expression of FCER1G predicts positive prognosis in multiple myeloma
Lin Fu, Zhiheng Cheng, Fen Dong, Liang Quan, Longzhen Cui, Yan Liu, Tiansheng Zeng, Wenhui Huang, Jinghong Chen, Ying Pang, Xu Ye, Guangsheng Wu, Tingting Qian, Yang Chen, Chaozeng Si
J. Cancer 2020; 11(5): 1182-1194. doi:10.7150/jca.37313
Abstract Full text PDF PubMed PMC

Down-regulation of tissue factor inhibits invasion and metastasis of non-small cell lung cancer
Qing Xia, Xu Zhang, Qianqian Chen, Xiangyun Chen, Junliang Teng, Changhui Wang, Ming Li, Lihong Fan
J. Cancer 2020; 11(5): 1195-1202. doi:10.7150/jca.37321
Abstract Full text PDF PubMed PMC

Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle
Rui Yang, Yang Du, Lei Wang, Zhiyuan Chen, Xiuheng Liu
J. Cancer 2020; 11(5): 1203-1211. doi:10.7150/jca.38173
Abstract Full text PDF PubMed PMC

Prognostic value of downregulated 5-hydroxymethylcytosine expression in renal cell carcinoma: a 10 year follow-up retrospective study
Song Chen, Qiang Zhou, Tongzu Liu, Weibing Zhang, Xian-Tao Zeng, Zhongqiang Guo
J. Cancer 2020; 11(5): 1212-1222. doi:10.7150/jca.38283
Abstract Full text PDF PubMed PMC

Proposal of predictive model on survival in unresectable pancreatic cancer receiving systemic chemotherapy
Noriko Ishii, Hiroki Nishikawa, Yoshinori Iwata, Hirayuki Enomoto, Hironori Tanaka, Nobuyuki Katakami, Takashi Nishimura, Hiroko Iijima, Shuhei Nishiguchi
J. Cancer 2020; 11(5): 1223-1230. doi:10.7150/jca.38861
Abstract Full text PDF PubMed PMC

Preventable lifestyle and eating habits associated with gastric adenocarcinoma: A case-control study
Lei Huang, Lei Chen, Zhong-Xuan Gui, Shun Liu, Zhi-Jian Wei, A-Man Xu
J. Cancer 2020; 11(5): 1231-1239. doi:10.7150/jca.39023
Abstract Full text PDF PubMed PMC

TRIM67 Promotes the Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Positively Regulating the Notch Pathway
Jun Jiang, Hongjiu Ren, Yitong Xu, Muli Wudu, Qiongzi Wang, Zongang Liu, Hongbo Su, Xizi Jiang, Yao Zhang, Bo Zhang, Xueshan Qiu
J. Cancer 2020; 11(5): 1240-1249. doi:10.7150/jca.38286
Abstract Full text PDF PubMed PMC

LMP1 Up-regulates Calreticulin to Induce Epithelial-mesenchymal Transition via TGF-β/Smad3/NRP1 Pathway in Nasopharyngeal Carcinoma Cells
Dongmei Ye, Junhui Zhu, Qiang Zhao, Wei Ma, Yiyang Xiao, Gaosheng Xu, Zhiwei Zhang
J. Cancer 2020; 11(5): 1257-1269. doi:10.7150/jca.37415
Abstract Full text PDF PubMed PMC

Nicotine Upregulates the Level of Mcl-1 through STAT3 in H1299 Cells
Maojun Zhou, Jinfeng Zhao, Qi Zhang, Xin Jin, Mingmei Liao, Lihua Zhang, Jiwei Wang, Manyi Yang
J. Cancer 2020; 11(5): 1270-1276. doi:10.7150/jca.35453
Abstract Full text PDF PubMed PMC

M2 Macrophages Promote HCC Cells Invasion and Migration via miR-149-5p/MMP9 Signaling
Guodong Liu, Lei Yin, Xiwu Ouyang, Ke Zeng, Yao Xiao, Yixiong Li
J. Cancer 2020; 11(5): 1277-1287. doi:10.7150/jca.35444
Abstract Full text PDF PubMed PMC

Identification of a Sixteen-gene Prognostic Biomarker for Lung Adenocarcinoma Using a Machine Learning Method
Baoshan Ma, Yao Geng, Fanyu Meng, Ge Yan, Fengju Song
J. Cancer 2020; 11(5): 1288-1298. doi:10.7150/jca.34585
Abstract Full text PDF PubMed PMC

Reviews

Nicotinic-nAChR signaling mediates drug resistance in lung cancer
Wan-Li Cheng, Kuan-Yuan Chen, Kang-Yun Lee, Po-Hao Feng, Sheng-Ming Wu
J. Cancer 2020; 11(5): 1125-1140. doi:10.7150/jca.36359
Abstract Full text PDF PubMed PMC

Antitumor functions and mechanisms of nitidine chloride in human cancers
Yue Cui, Linhui Wu, Ruoxue Cao, Hui Xu, Jun Xia, Z Peter Wang, Jia Ma
J. Cancer 2020; 11(5): 1250-1256. doi:10.7150/jca.37890
Abstract Full text PDF PubMed PMC

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