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Volume 12 (3); 2021

Research Papers

Ethanol Extracted from Radix of Actinidia Chinensis Inhibits Human Colon Tumor Through Inhibiting Notch-signaling Pathway
Wanle Hu, Chenchen Wu, Chenchen Yuan, Minyuan Chen, Chun Jin, Chenguo Zheng
J. Cancer 2021; 12(3): 622-629. doi:10.7150/jca.51275
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The oncogenic and prognostic role of PDK1 in the progression and metastasis of ovarian cancer
Shasha Yao, Wenwen Shang, Lei Huang, Rui Xu, Ming Wu, Fang Wang
J. Cancer 2021; 12(3): 630-643. doi:10.7150/jca.47278
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Genomic and clinical characteristics of MET exon14 alterations in a large cohort of Chinese cancer patients revealed distinct features and a novel resistance mechanism for crizotinib
Tianli Cheng, Zhongping Gu, Danni Song, Sisi Liu, Xiaoling Tong, Xue Wu, Zhifeng Lin, Wei Hong
J. Cancer 2021; 12(3): 644-651. doi:10.7150/jca.49391
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A Double-Edged Sword: The Anti-Cancer Effects of Emodin by Inhibiting the Redox-Protective Protein MTH1 and Augmenting ROS in NSCLC
Divya Wahi, Deepika Soni, Abhinav Grover
J. Cancer 2021; 12(3): 652-681. doi:10.7150/jca.41160
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N6-methyladenosine RNA methylation regulators contribute to the progression of prostate cancer
Qunying Wu, Xing Xie, Yiming Huang, Shanshan Meng, Youcheng Li, Huifeng Wang, Yanling Hu
J. Cancer 2021; 12(3): 682-692. doi:10.7150/jca.46379
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Diagnostic and prognostic value of FOXD1 expression in head and neck squamous cell carcinoma
Shijie Qiu, Dan Li, Zhisen Shen, Qun Li, Yi Shen, Hongxia Deng, Yidong Wu, Chongchang Zhou
J. Cancer 2021; 12(3): 693-702. doi:10.7150/jca.47978
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Decoding Immune Heterogeneity of Melanoma and identifying immune-prognostic hub genes
Yu Zhang, Siyu Hao, Yingli Gao, Weina Sun, Yuzhen Li
J. Cancer 2021; 12(3): 703-716. doi:10.7150/jca.50277
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Nogo-B receptor is required for stabilizing TGF-β type Ireceptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer
Donghua Wu, Baofeng Zhao, Yang Song, Xinming Chi, Hailu Fu, Tiantong Guan, Liyuan Zhang, Xueguang Yang, Ke Hu, Rong Huang, Xiaomeng Jin, Qing Robert Miao, Shujuan Shao
J. Cancer 2021; 12(3): 717-725. doi:10.7150/jca.50483
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MRI-Based Radiomic Model for Preoperative Risk stratification in Stage I Endometrial Cancer
Jingya Chen, Hailei Gu, Weimin Fan, Yaohui Wang, Shuai Chen, Xiao Chen, Zhongqiu Wang
J. Cancer 2021; 12(3): 726-734. doi:10.7150/jca.50872
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Identification of Seven Cell Cycle-Related Genes with Unfavorable Prognosis and Construction of their TF-miRNA-mRNA regulatory network in Breast Cancer
Zhipeng Hong, Qinglan Wang, Chengye Hong, Meimei Liu, Pengqin Qiu, Rongrong Lin, Xiaolan Lin, Fangfang Chen, Qiuhuang Li, Lingling Liu, Chuan Wang, Debo Chen
J. Cancer 2021; 12(3): 740-753. doi:10.7150/jca.48245
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Diagnostic Accuracy of MRI for Detecting Cervical Invasion in Patients with Endometrial Carcinoma: A Meta-Analysis
Qiu Bi, Guoli Bi, Junna Wang, Jie Zhang, Hongliang Li, Xiarong Gong, Lixiang Ren, Kunhua Wu
J. Cancer 2021; 12(3): 754-764. doi:10.7150/jca.52797
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Comparison of Endoscopic Submucosal Dissection Application on Mucosal Tumor and Subepithelial Tumor in stomach
Wen-Hung Hsu, Tzung-Shiun Wu, Meng-Shu Hsieh, Yu-Min Kung, Yao-Kuang Wang, Jeng-Yih Wu, Fang-Jung Yu, Chao-Hung Kuo, Yu-Chung Su, Jaw-Yuan Wang, Deng-Chyang Wu, Huang-Ming Hu
J. Cancer 2021; 12(3): 765-770. doi:10.7150/jca.47653
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Upregulation of miR-1254 promotes Hepatocellular Carcinoma Cell Proliferation, Migration, and Invasion via Inactivation of the Hippo-YAP signaling pathway by decreasing PAX5
Xu Lu, Chao Yang, Yuanchang Hu, Jian Xu, Chengyu Shi, Jianhua Rao, Weixin Yu, Feng Cheng
J. Cancer 2021; 12(3): 771-789. doi:10.7150/jca.49680
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A Novel Nomogram for Predicting the Survival of Patients with Invasive Upper Tract Urothelial Carcinoma
Zaishang Li, Xueying Li, Yonghong Li, Ying Liu, Peng Du, Zenqing Liu, Kefeng Xiao
J. Cancer 2021; 12(3): 790-798. doi:10.7150/jca.50419
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Establishment and Validation of a Preoperative MRI-based Nomogram for Predicting the Risk of Malignancy in Patients with Breast Tumor
Jianguo Lai, Jinjiang Lin, Hongli Wang, Yi Sun, Yudong Li, Huan Tian, Shiyu Shen, Cui Tan, Huanhuan Liu, Fengyan Yu
J. Cancer 2021; 12(3): 799-806. doi:10.7150/jca.49441
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Overexpression of TC2N is associated with poor prognosis in gastric cancer
Jianbo Xu, Xinde Ou, Jin li, Qinbo Cai, Kaiyu Sun, Jingning Ye, Jianjun Peng
J. Cancer 2021; 12(3): 807-817. doi:10.7150/jca.50653
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ADP-Ribosylation Factor Like GTPase 4C (ARL4C) augments stem-like traits of glioblastoma cells by upregulating ALDH1A3
Qian Chen, Wen-juan Fu, Xiao-peng Tang, Lu Wang, Qin Niu, Shuai Wang, Yong Lin, Mian-fu Cao, Rong Hu, Hai-Yan Wen, Yan Wang, Xia Zhang, Xiao-Hong Yao
J. Cancer 2021; 12(3): 818-826. doi:10.7150/jca.45052
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Hypoxia Inducible Factor-1alpha (HIF-1A) plays different roles in Gallbladder Cancer and Normal Gallbladder Tissues
Youliang Wu, Delong Meng, Yexiang You, Ruochuan Sun, Min Fu, Qiang Yan, Shangxin Zhang, Zheng Fang, Junjun Bao, Yongxiang Li
J. Cancer 2021; 12(3): 827-839. doi:10.7150/jca.46749
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New novel non-MHC genes were identified for cervical cancer with an integrative analysis approach of transcriptome-wide association study
Haimiao Chen, Ting Wang, Shuiping Huang, Ping Zeng
J. Cancer 2021; 12(3): 840-848. doi:10.7150/jca.47918
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Genomic variants in Fas-mediated apoptosis pathway predict a poor response to Platinum-based Chemotherapy for Chinese Gastric Cancer Patients
Tingting Zhao, Wei Li, Jinfei chen, Weisong Qin
J. Cancer 2021; 12(3): 849-859. doi:10.7150/jca.48120
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Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway
Lidong Wang, Yonglian Huang, Chenxi Liu, Mingyue Guo, Zhennan Ma, Jingni He, Ailian Wang, Xiaodan Sun, Zhen Liu
J. Cancer 2021; 12(3): 860-873. doi:10.7150/jca.48141
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Identifying Key Genes for Nasopharyngeal Carcinoma by Prioritized Consensus Differentially Expressed Genes Caused by Aberrant Methylation
Yunqin Chen, Chun Zhou, Huabin Li, Hong Li, Yixue Li
J. Cancer 2021; 12(3): 874-884. doi:10.7150/jca.49392
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Prognostic implication of glycolysis related gene signature in non-small cell lung cancer
Jie Yao, Rui Li, Xiao Liu, Xijia Zhou, Jianping Li, Tingting Liu, Chen Huo, Yiqing Qu
J. Cancer 2021; 12(3): 885-898. doi:10.7150/jca.50274
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Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR
liuhai Zheng, linzhi Li, jun Xie, hai Jin, naishuo Zhu
J. Cancer 2021; 12(3): 899-911. doi:10.7150/jca.50443
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A phase II study of gemcitabine, erlotinib and S-1 in patients with advanced pancreatic cancer
Boram Han, Bum Jun Kim, Hyeong Su Kim, Dae Ro Choi, Byoung Yong Shim, Kyung Hee Lee, Jin Won Kim, Jung Han Kim, Hunho Song, Jong Hyeok Kim, Choong Kee Park, Jung Woo Lee, Min-Jeong Kim, Dae Young Zang
J. Cancer 2021; 12(3): 912-917. doi:10.7150/jca.50514
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Upregulated expression of serum exosomal hsa_circ_0026611 is associated with lymph node metastasis and poor prognosis of esophageal squamous cell carcinoma
Shuang Liu, Zheng Lin, Wenqing Rao, Jing Zheng, Qianwen Xie, Yulan Lin, Xi Lin, Huilin Chen, Yuanmei Chen, Zhijian Hu
J. Cancer 2021; 12(3): 918-926. doi:10.7150/jca.50548
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A novel prognosis marker based on combined preoperative carcinoembryonic antigen and systemic inflammatory response for resectable gastric cancer
Yubin Ma, Junpeng Lin, Jianxian Lin, Junfang Hou, Qin Xiao, Fang Yu, Zhijun Ma, Ping Li, Ruhong Tu, Jianwei Xie, Chaohui Zheng, Su Yan, Changming Huang
J. Cancer 2021; 12(3): 927-935. doi:10.7150/jca.52299
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Novel biomarkers and prediction model for the pathological complete response to neoadjuvant treatment of triple-negative breast cancer
Yiqun Han, Jiayu Wang, Binghe Xu
J. Cancer 2021; 12(3): 936-945. doi:10.7150/jca.52439
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The added value of CA125 normalization before interval debulking surgery to the chemotherapy response score for the prognostication of ovarian cancer patients receiving neoadjuvant chemotherapy for advanced disease
Wei-feng Liang, Li-juan Wang, Hui Li, Chang-hao Liu, Miao-fang Wu, Jing Li
J. Cancer 2021; 12(3): 946-953. doi:10.7150/jca.52711
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Review

The oncogenic role of protein kinase D3 in cancer
Yan Liu, Hang Song, Yehui Zhou, Xinxing Ma, Jing Xu, Zhenghong Yu, Liming Chen
J. Cancer 2021; 12(3): 735-739. doi:10.7150/jca.50899
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