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Volume 13 (8); 2022

Research Papers

Graphic abstract

ADAR1 Prevents R-loop Accumulation-Driven ATR Pathway Activation in Ovarian Cancer
Hanwei Cui, Qian Yi, Min Tian, Hai Ting Yang, Yuteng Liang, Jie Huang, Qi Zeng, Weichao Sun, Jian Han, Jianxin Guo, Zhiying Yu, Wenlan Liu, Xiufeng Ye
J. Cancer 2022; 13(8): 2397-2412. doi:10.7150/jca.72108
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Fuzzy Planar Cell Polarity Gene (FUZ) Promtes Cell Glycolysis, Migration, and Invasion in Non-small Cell Lung Cancer via the Phosphoinositide 3-Kinase/Protein Kinase B Pathway
Shu Wang, Hui Zhang, Bulin Du, Xuena Li, Yaming Li
J. Cancer 2022; 13(8): 2419-2429. doi:10.7150/jca.63152
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Association between Timing and Duration of Adjuvant Chemotherapy and Colorectal Cancer Survival in Korea, 2011-2014: A Nationwide Study based on the Health Insurance Review and Assessment Service Database
Jin Hwa Choi, Ji Sung Lee, Sun Kyung Baek, Jong Gwang Kim, Tae Won Kim, Seung Kook Sohn, Mi Yeon Kang, Sang-Cheol Lee, In Gyu Hwang
J. Cancer 2022; 13(8): 2440-2446. doi:10.7150/jca.71141
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Predictive value of indicator of CA125 combined with D-dimer (ICD) for lymph node metastasis in patients with ovarian cancer: A two center cohort study
Li Zhang, Zongyu Guan, Yi Yin, Chaoyang Ou, Hongyan Qian, Min Tang, Aiguo Shen
J. Cancer 2022; 13(8): 2447-2456. doi:10.7150/jca.70737
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Prognostic Impact of Tumor Budding in Intrahepatic Cholangiocellular Carcinoma
Klara-Luisa Budau, Carlie S. Sigel, Luise Bergmann, Anne-Marie Lüchtenborg, Ulrich Wellner, Oliver Schilling, Martin Werner, Laura Tang, Peter Bronsert
J. Cancer 2022; 13(8): 2457-2471. doi:10.7150/jca.63008
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Androgen receptor expression in patients with triple negative breast cancer treated with neoadjuvant chemotherapy: a single institution study
Nithya Sridhar, Chad Glisch, Zeeshan Jawa, Lubna N. Chaudhary, Sailaja Kamaraju, John Burfeind, John Charlson, Christopher R. Chitambar, Julie M. Jorns, Yee Chung Cheng
J. Cancer 2022; 13(8): 2472-2476. doi:10.7150/jca.67536
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The Mitochondrial Protein C1QBP Promotes Hepatocellular Carcinoma Progression by Enhancing Cell Survival, Migration and Invasion
Guoxin Hou, Zhimin Lu, Zhen Wang, Xinmei Yang
J. Cancer 2022; 13(8): 2477-2489. doi:10.7150/jca.69379
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New Clues to Prognostic Biomarkers of Four Hematological Malignancies
Samson Pandam Salifu, Albert Doughan
J. Cancer 2022; 13(8): 2490-2503. doi:10.7150/jca.69274
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ORC6 acts as a biomarker and reflects poor outcome in clear cell renal cell carcinoma
Qiufeng Pan, Fuchun Li, Yi Ding, Haoxuan Huang, Ju Guo
J. Cancer 2022; 13(8): 2504-2514. doi:10.7150/jca.71313
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A new classifier constructed with platelet features for malignant and benign pulmonary nodules based on prospective real-world data
Ruiling Zu, Lin Wu, Rong Zhou, Xiaoxia wen, Bangrong Cao, Shan Liu, Guishu Yang, Ping Leng, Yan Li, Li Zhang, Xiaoyu Song, Yao Deng, Kaijiong Zhang, Chang Liu, Yuping Li, Jian Huang, Dongsheng Wang, Guiquan zhu, Huaichao Luo
J. Cancer 2022; 13(8): 2515-2527. doi:10.7150/jca.67428
[Abstract] [Full text] [PDF]


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GLUT1 Regulates the Tumor Immune Microenvironment and Promotes Tumor Metastasis in Pancreatic Adenocarcinoma via ncRNA-mediated Network
Fengjiao Li, Chong He, Hanming Yao, Weiling Liang, Xijiu Ye, Jianmin Ruan, Lijun Lin, Jinmao Zou, Shurui Zhou, Yuzhou Huang, Yaqing Li, Shaojie Chen, Kaihong Huang, Guoda Lian, Shangxiang Chen
J. Cancer 2022; 13(8): 2540-2558. doi:10.7150/jca.72161
[Abstract] [Full text] [PDF]


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Hexokinase 2 Promotes Cell Proliferation and Tumor Formation through the Wnt/β-catenin Pathway-mediated Cyclin D1/c-myc Upregulation in Epithelial Ovarian Cancer
Xian Liu, Xiaohang Zuo, Xiaoli Sun, Xueye Tian, Yue Teng
J. Cancer 2022; 13(8): 2559-2569. doi:10.7150/jca.71894
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RPL17 Promotes Colorectal Cancer Proliferation and Stemness through ERK and NEK2/β-catenin Signaling Pathways
Min Ji Ko, Yu-Ri Seo, Daekwan Seo, So-Young Park, Ji Hae Seo, Eun-Hye Jeon, Sang-Woo Kim, Keon Uk Park, Deog-Bon Koo, Shin Kim, Jae-Hoon Bae, Dae-Kyu Song, Chi Heum Cho, Kwang Seok Kim, Yun-Han Lee
J. Cancer 2022; 13(8): 2570-2583. doi:10.7150/jca.69428
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Transketolase Serves as a Biomarker for Poor Prognosis in Human Lung Adenocarcinoma
Cong Niu, Wenjia Qiu, Xiangyang Li, Hongqing Li, Ji'an Zhou, Huili Zhu
J. Cancer 2022; 13(8): 2584-2593. doi:10.7150/jca.69583
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Anticancer Efficacy and Mechanisms of a Dual Targeting of Norepinephrine Transporter and Thyrointegrin αvβ3 Antagonist in Neuroblastoma
Kavitha Godugu, Ozlem O. Karakus, Kazutoshi Fujioka, Gennadi V. Glinsky, Shaker A. Mousa
J. Cancer 2022; 13(8): 2594-2606. doi:10.7150/jca.72522
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3,3'-Diindolylmethane plus Eflornithine suppress DNA Replication and Cell Cycle in Esophageal Squamous Cell Carcinoma in vivo
Fayang Ma, Fangfang Liu, Wenna Nie, Kyle Laster, Xueli Tian, Bingbing Lu, Zushi Geng, Ruihua Bai, Dong Joon Kim, Kangdong Liu, Zigang Dong
J. Cancer 2022; 13(8): 2607-2619. doi:10.7150/jca.65506
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IL-1β-Triggered Long Non-coding RNA CHRF Induces Non-Small Cell Lung Cancer by Modulating the microRNA-489/Myd88 Axis
Yamei Zhang, Yabo Zhang, Qianglin Zeng, Ci Li, Hui Zhou, Junying Liu, Zheng Shi, Li Ma
J. Cancer 2022; 13(8): 2620-2630. doi:10.7150/jca.63256
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Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Lung Adenocarcinoma
Hua Huang, Guangsheng Zhu, Ruifeng Shi, Yongwen Li, Zihe Zhang, Songlin Xu, Chen Chen, Peijun Cao, Zhenhua Pan, Hongbing Zhang, Minghui Liu, Hongyu Liu, Jun Chen
J. Cancer 2022; 13(8): 2631-2643. doi:10.7150/jca.70725
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The Curcumin Analog Da0324 Inhibits the Proliferation of Gastric Cancer Cells via HOTAIRM1/miR-29b-1-5p/PHLPP1 Axis
Fanfan Xu, Mengxia Chen, Hao Chen, Nan Wu, Qinqin Qi, Xiujiao Jiang, Daoquan Fang, Qian Feng, Rong Jin, Lei Jiang
J. Cancer 2022; 13(8): 2644-2655. doi:10.7150/jca.69970
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Effect of Atezolizumab plus Bevacizumab in Patients with Hepatocellular Carcinoma Harboring CTNNB1 Mutation in Early Clinical Experience
Keita Ogawa, Hiroaki Kanzaki, Tetsuhiro Chiba, Junjie Ao, Na Qiang, Yaojia Ma, Jiaqi Zhang, Sae Yumita, Takamasa Ishino, Hidemi Unozawa, Motoyasu Kan, Terunao Iwanaga, Miyuki Nakagawa, Kisako Fujiwara, Naoto Fujita, Takafumi Sakuma, Keisuke Koroki, Yuko Kusakabe, Kazufumi Kobayashi, Naoya Kanogawa, Soichiro Kiyono, Masato Nakamura, Takayuki Kondo, Tomoko Saito, Ryo Nakagawa, Sadahisa Ogasawara, Eiichiro Suzuki, Shingo Nakamoto, Ryosuke Muroyama, Tatsuo Kanda, Hitoshi Maruyama, Naoya Mimura, Jun Kato, Shinichiro Motohashi, Naoya Kato
J. Cancer 2022; 13(8): 2656-2661. doi:10.7150/jca.71494
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LncRNA AC098934 promotes proliferation and invasion in lung adenocarcinoma cells by combining METTL3 and m6A modifications
Shiqing Huang, Mingyang Jin, Xiaolin Lan, Junyun Long Wu, Zhiwen Zhang, Jingjing Zhao, Yepeng Li
J. Cancer 2022; 13(8): 2662-2672. doi:10.7150/jca.69406
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Fasting serum glucose and lymph node metastasis in non-diabetic PTC patients: a 10-Year multicenter retrospective study
Yushu Liu, Jiantao Gong, Yanyi Huang, Shanshan Xing, Ling Chen, Tao Yi, Zhiyong Wang, Yunxia Lv
J. Cancer 2022; 13(8): 2673-2682. doi:10.7150/jca.71514
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Construction of a novel radiosensitivity- and ferroptosis-associated gene signature for prognosis prediction in gliomas
Yandong Xie, Yong Xiao, Yuyang Liu, Xueying Lu, Zhen Wang, Shuo Sun, Liang Liu, Xianglong Tang, Hong Xiao, Hongyi Liu
J. Cancer 2022; 13(8): 2683-2693. doi:10.7150/jca.72893
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TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-β to Mediate EMT in Triple-Negative Breast Cancer
Jiaci Tong, Haoran Li, Ye Hu, ZuoWei Zhao, Man Li
J. Cancer 2022; 13(8): 2694-2704. doi:10.7150/jca.65822
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Reviews

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Research progress in the role and mechanism of LPCAT3 in metabolic related diseases and cancer
Gaoxuan Shao, Yufan Qian, Lu Lu, Ying Liu, Tao Wu, Guang Ji, Hanchen Xu
J. Cancer 2022; 13(8): 2430-2439. doi:10.7150/jca.71619
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FSCN1 acts as a promising therapeutic target in the blockade of tumor cell motility: a review of its function, mechanism, and clinical significance
Zhongxun Li, Jiao Shi, Nannan Zhang, Xiwang Zheng, Yukun Jin, Shuxin Wen, Wanglai Hu, Yongyan Wu, Wei Gao
J. Cancer 2022; 13(8): 2528-2539. doi:10.7150/jca.67977
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Errata

Overexpression of TC2N is associated with poor prognosis in gastric cancer: Erratum
Jianbo Xu, Xinde Ou, Jin li, Qinbo Cai, Kaiyu Sun, Jingning Ye, Jianjun Peng
J. Cancer 2022; 13(8): 2413. doi:10.7150/jca.73345
[Abstract] [Full text] [PDF]


TGF-β1-Induced Upregulation of MALAT1 Promotes Kazakh's Esophageal Squamous Cell Carcinoma Invasion by EMT: Erratum
Qing Liu, Shutao Zheng, Yumei Chen, Tao Liu, Xiujuan Han, Xiao Zhang, Tongxue Shen, Xiaomei Lu
J. Cancer 2022; 13(8): 2414. doi:10.7150/jca.73596
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Effects of Galectin-1 on Biological Behavior in Cervical Cancer: Erratum
Mandika Chetry, Yizuo Song, Chunyu Pan, Ruyi Li, Jianan Zhang, Xueqiong Zhu
J. Cancer 2022; 13(8): 2415-2417. doi:10.7150/jca.73685
[Abstract] [Full text] [PDF]

Retraction

Retraction: MiR-211-5p Inhibits the Biological Behaviors of Colorectal Cancer via SPARC-Related Growth Factor Pathways

J. Cancer 2022; 13(8): 2418. doi:10.7150/jca.73906
[Abstract] [Full text] [PDF]