Front cover

◂ Last issue Next issue ▸ Archive Cover PDF   

Volume 16 (3); 2025

Research Papers

Graphic abstract

A Novel Oncolytic Virus Formulation Based on Mesenchymal Stem Cell-Derived Vesicles for Tumor Therapy
Fanjun Zeng, Yucheng Huang, Bin Xu, Lintong Yao, Yiqing Zhang, Zhiping Gao, Yingli Luo
J. Cancer 2025; 16(3): 700-707. doi:10.7150/jca.104066
Full text PDF PubMed PMC

Graphic abstract

Longikaurin A, a natural ent-kaurane, suppresses proliferation, invasion and tumorigenicity in oral squamous cell carcinoma cell by via inhibiting PI3K/Akt pathway in vitro and in vivo
Yiming Luo, Zixuan Wang, Yufei Li, Linlin Zhang
J. Cancer 2025; 16(3): 708-719. doi:10.7150/jca.102125
Full text PDF PubMed PMC

Graphic abstract

A Novel Competing Endogenous RNA Network Reveals Potential Mechanisms and Biomarkers of Chemoresistance in Lung Adenocarcinoma
Weisha Liu, Hanxiao Zhou, Yue Qi, Peng Wang, Shangwei Ning, Yue Huang, Liuying Wang, Lei Cao, Kang Li
J. Cancer 2025; 16(3): 720-734. doi:10.7150/jca.102148
Full text PDF PubMed PMC

Graphic abstract

Third generation vs first generation EGFR-TKIs in the first line treatment for EGFR-mutated locally advanced or metastatic non-small cell lung cancer: a meta-analysis based on randomized controlled trials
Wenjie Hu, Yi Qin, Taoming Dong, Xueying Lin, Yuan Chen, Wenxiong Zhang, Tanggui Feng
J. Cancer 2025; 16(3): 735-747. doi:10.7150/jca.99319
Full text PDF PubMed PMC

Graphic abstract

HIF-1α Mediated Regulation of Glioblastoma Malignant Phenotypes through CD47 Protein: Understanding Functions and Mechanisms
Qijia Tan, Feng Li, Jun Wang, Yuxi Zou, Yanping Tang, Yingqian Cai, Xiaodan Jiang
J. Cancer 2025; 16(3): 750-764. doi:10.7150/jca.101050
Full text PDF PubMed PMC

Graphic abstract

Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways
Qiang Yuan, Hangyu Jiang, Maofei Zhu, Yueming Chu, Yan Zhang, Jun Bie, Lin Li
J. Cancer 2025; 16(3): 765-783. doi:10.7150/jca.101798
Full text PDF PubMed PMC

Graphic abstract

The Clinical Prediction Value of the Ubiquitination Model Reflecting the Microenvironment Infiltration and Drug Sensitivity in Breast Cancer
Hai-Yan Ma, Jun-Ming Cao, Yuan-Yuan Zhang, Jin-Shuo Yang, Xin Wang, Yue Yu
J. Cancer 2025; 16(3): 784-801. doi:10.7150/jca.101525
Full text PDF PubMed PMC

Graphic abstract

Elevated Serum IL-6 as a Negative Prognostic Biomarker in Glioblastoma: Integrating Bioinformatics and Clinical Validation
Sup Kim, Kyung Hwan Kim, Hee-won Jung, Eun-Oh Jeong, Han-Joo Lee, Jeanny Kwon, Hyon-jo Kwon, Seung-Won Choi, Hyeon-Song Koh, Seon-Hwan Kim
J. Cancer 2025; 16(3): 802-811. doi:10.7150/jca.104759
Full text PDF PubMed PMC

Graphic abstract

LncRNA GATA3-AS1 Promotes Bladder Uroepithelial Cancer Progression by Stabilizing DDX5
Yatao Duan, Zonghang Liu, Yongliang Ma, Pan Qi, Yanli Guo, Aili Zhang
J. Cancer 2025; 16(3): 835-847. doi:10.7150/jca.104034
Full text PDF PubMed PMC

Graphic abstract

Mutant Pattern of p53 as a Feasible Predictor of Distant Metastasis Following Curative Gastrectomy for Advanced-stage Gastric Cancer
Quanming An, Lili Miao, Jia Wu, Junwen Ma
J. Cancer 2025; 16(3): 860-875. doi:10.7150/jca.98563
Full text PDF PubMed PMC

Graphic abstract

Hesperidin inhibits colon cancer progression by downregulating SLC5A1 to suppress EGFR phosphorylation
Xiaodong Li, Zhao Wu, Lebin Yuan, Xing Chen, He Huang, Fei Cheng, Wei Shen
J. Cancer 2025; 16(3): 876-887. doi:10.7150/jca.104867
Full text PDF PubMed PMC

Graphic abstract

Elucidating the Role of Estrogen Effects in Leukemia: Insights from Single-Cell RNA Sequencing and Mendelian Randomization
Jiahan Zhao, Yang Yu, Cun Liu, Ruijuan Liu, Mengxuan Sun, Jing Zhuang, Changgang Sun, Qibiao Wu
J. Cancer 2025; 16(3): 888-897. doi:10.7150/jca.100610
Full text PDF PubMed PMC

Graphic abstract

Single-cell analysis unveils cell subtypes of acral melanoma cells at the early and late differentiation stages
Mengyuan Hou, Zhijie Zhao, Shuxiao Li, Ziwei Zhang, Xin Li, Yichi Zhang, Wenyi Huang, Li Li, Wenjing Xi, Feiteng Liang, Li Lin, Yan Zhang, Gang Chai
J. Cancer 2025; 16(3): 898-916. doi:10.7150/jca.102045
Full text PDF PubMed PMC

Graphic abstract

Development of a Novel four-gene Model for Monitoring the Progression from Metabolic Dysfunction-associated Steatotic Liver Disease to Hepatocellular Carcinoma in Males
Yuchuan Jiang, Jiejian Chen, Lin Xu, Lin Lv, Xiaoning Gan
J. Cancer 2025; 16(3): 917-931. doi:10.7150/jca.100724
Full text PDF PubMed PMC

Graphic abstract

Uncovering the Role of ALDH1A2 in Prostate Cancer: Insights from Genetic and Expression Analyses
Chi-Fen Chang, Bo-Ying Bao, Te-Ling Lu, Lih-Chyang Chen, Yei-Tsung Chen, Tzu-Ping Lin
J. Cancer 2025; 16(3): 932-941. doi:10.7150/jca.104705
Full text PDF PubMed PMC

Graphic abstract

Efficacy and Safety of Immune Checkpoint Inhibitor Rechallenge in the Treatment of Esophageal Squamous Cell Cancer
Xiaojing Zhang, Jingze Zhang, Junyi He, Xiao Zhong, Jinming Yu, Linlin Wang
J. Cancer 2025; 16(3): 943-951. doi:10.7150/jca.104380
Full text PDF PubMed PMC

Graphic abstract

Sensitivity of renal cell carcinoma to cuproptosis: a bioinformatics analysis and experimental verification
Hongfang Li, Chanjuan Zhang, Neng Zhu, Yaning Shi, Li Qin
J. Cancer 2025; 16(3): 952-968. doi:10.7150/jca.103708
Full text PDF PubMed PMC

Graphic abstract

Distinct roles of small extracellular vesicles from resident and infiltrating macrophages on glioma growth and mobility
Chu-Hsuan Chen, Sheng-Yun Hsu, Wen-Jui Yu, Chi-Shiun Chiang, Ching-Fang Yu
J. Cancer 2025; 16(3): 969-981. doi:10.7150/jca.103595
Full text PDF PubMed PMC

Graphic abstract

KLRD1 (CD94): A Prognostic Biomarker and Therapeutic Candidate in Head and Neck Squamous Cell Carcinoma
Chengyuan Dong, Ziyou Lin, Yunzhao Hu, Qun Lu
J. Cancer 2025; 16(3): 982-995. doi:10.7150/jca.104762
Full text PDF PubMed PMC

Graphic abstract

Radiation Therapy Improves Survival in Patients with Distant Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective Study
Mengwen Wang, Baitian Zhao, Amin Huang, Ming Song, Jia Wang, Panpan Liu
J. Cancer 2025; 16(3): 996-1007. doi:10.7150/jca.105254
Full text PDF PubMed PMC

Graphic abstract

ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway
Shun Chen, Jiancheng He, Hanxu Gao, Xian Gao, Lingchen Dai, Junjie Chen, Zhenyu Sha
J. Cancer 2025; 16(3): 1008-1019. doi:10.7150/jca.103093
Full text PDF PubMed PMC

Graphic abstract

Investigating causal relationships of blood and urine biomarkers with urological cancer risks: a mendelian randomization study and colocalization analyses
Jian Li, Bing Yang, Lei Guo, Wenqi Huang, Qiong Hu, Hongting Yan, Rong Tan, Dongxin Tang
J. Cancer 2025; 16(3): 1020-1031. doi:10.7150/jca.103669
Full text PDF PubMed PMC

Reviews

Graphic abstract

Research Progress of DNA Methylation Markers for Endometrial Carcinoma Diagnosis
Haoning Zheng, Cuisong Yu, Lu Yang, Fenghua Zhou, Aijun Liu
J. Cancer 2025; 16(3): 812-820. doi:10.7150/jca.104214
Full text PDF PubMed PMC

Graphic abstract

Unlocking the Hidden Potential of Cancer Therapy Targeting Lysine Succinylation
Zhuomeng Zheng, Peiyao Xiao, Jiale Kuang, Zhiyu Wang, Xinyu Wang, Da Huang, Yuxuan Guo, Li Zhou, Yiyuan Yang, Siyu Ding, Chanjuan Zheng, Yian Wang, Shujun Fu, Xiyun Deng
J. Cancer 2025; 16(3): 821-834. doi:10.7150/jca.105849
Full text PDF PubMed PMC

Erratum

MRPS16 facilitates tumor progression via the PI3K/AKT/Snail signaling axis: Erratum
Zhen Wang, Junjun Li, Xiaobing Long, Liwu Jiao, Minghui Zhou, Kang Wu
J. Cancer 2025; 16(3): 748-749. doi:10.7150/jca.104449
Full text PDF PubMed PMC

Popup Image

©2025 Ivyspring International Publisher. Terms of use