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Volume 12 (24); 2021

Research Papers

Graphic abstract

Nomogram Models for Predicting Risk and Prognosis of Newly Diagnosed Ovarian Cancer Patients with Liver Metastases - A Large Population-Based Real-World Study
Gui-Min Hou, Chuang Jiang, Jin-peng Du, Chang Liu, Xiang-zheng Chen, Ke-fei Yuan, Hong Wu, Yong Zeng
J. Cancer 2021; 12(24): 7255-7265. doi:10.7150/jca.64255
[Abstract] [Full text] [PDF]


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ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2
Hong-Li Yang, Cong Xu, Yi-Kun Yang, Wen-Qiang Tang, Min Hong, Li Pan, Hai-Ying Chen
J. Cancer 2021; 12(24): 7266-7276. doi:10.7150/jca.63919
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CPNE3 regulates the cell proliferation and apoptosis in human Glioblastoma via the activation of PI3K/AKT signaling pathway
Dainan Zhang, Xiaoyin Wang, Xi Wang, Zemin Wang, Shunchang Ma, Chuanbao Zhang, Shaomin Li, Wang Jia
J. Cancer 2021; 12(24): 7277-7286. doi:10.7150/jca.60049
[Abstract] [Full text] [PDF]


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β-arrestin2 regulating β2-adrenergic receptor signaling in hepatic stellate cells contributes to hepatocellular carcinoma progression
Xiu-Qin Li, Wen-Ting Peng, Shan Shan, Jing-Jing Wu, Nan Li, Jia-Jia Du, Jia-Chang Sun, Ting-Ting Chen, Wei Wei, Wu-Yi Sun
J. Cancer 2021; 12(24): 7287-7299. doi:10.7150/jca.59291
[Abstract] [Full text] [PDF]


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Mutational Characterization of Colorectal Cancer from Korean Patients with Targeted Sequencing
Jongmin Lee, Sangtae Choi, Donghae Jung, YunJae Jung, Jung Ho Kim, Sungwon Jung, Won-Suk Lee
J. Cancer 2021; 12(24): 7300-7310. doi:10.7150/jca.61324
[Abstract] [Full text] [PDF]


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LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer
Zhengchao Shen, Yingying Pan, Peng Chen, Bin Jiang, Xiaosan Fang, Yaqi Jiang
J. Cancer 2021; 12(24): 7311-7319. doi:10.7150/jca.62211
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Prognostic Impact of Preoperative Renal Insufficiency on Metastasis-Free Survival after Radical Cystectomy
Jungyo Suh, Hyeong Dong Yuk, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyeon Ku
J. Cancer 2021; 12(24): 7320-7325. doi:10.7150/jca.61847
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Helicobacter pylori associated aberrant methylation genes in blood leukocyte and gastric mucosa
Yang Zhang, Duo Chen, Lian Zhang, Jun-Ling Ma, Tong Zhou, Zhe-Xuan Li, Wei-Dong Liu, Wei-Cheng You, Kai-Feng Pan
J. Cancer 2021; 12(24): 7326-7333. doi:10.7150/jca.64613
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Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway
Zhiyong Li, Yunning Huang, Yuanyi Xu, Xiaofei Wang, Honghong Wang, Shuai Zhao, Han Liu, Guangfu Yu, Xiangming Che
J. Cancer 2021; 12(24): 7334-7348. doi:10.7150/jca.61031
[Abstract] [Full text] [PDF]


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Downregulation of LOX promotes castration-resistant prostate cancer progression via IGFBP3
Xuanrong Chen, Yi Shao, Wanqing Wei, Haishan Shen, Yang Li, Yutong Chen, Qianwang Ma, Hanlin Li, Zhao Yang, Yuanjie Niu, Zhiqun Shang
J. Cancer 2021; 12(24): 7349-7357. doi:10.7150/jca.61131
[Abstract] [Full text] [PDF]


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Mitochondrial Dynamics Mediated by DRP1 and MFN2 Contributes to Cisplatin Chemoresistance in Human Ovarian Cancer SKOV3 cells
Guang-Ping Zou, Chun-Xia Yu, Sheng-Lan Shi, Qiu-Gen Li, Xiao-Hua Wang, Xin-Hui Qu, Zhang-Jian Yang, Wei-Rong Yao, Dan-Dan Yan, Li-Ping Jiang, Yu-Ying Wan, Xiao-Jian Han
J. Cancer 2021; 12(24): 7358-7373. doi:10.7150/jca.61379
[Abstract] [Full text] [PDF]


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Clinicalpathologic and Prognostic Significance of CGI-58 in Endometrial Cancer
Zhengzheng Shi, Xishao Luo, Hongqin Zhao, Baoyou Huang, Yuanqiu Wang, Xu Chen, Jiangtao Yu
J. Cancer 2021; 12(24): 7374-7379. doi:10.7150/jca.61905
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Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1
Juan Wang, Xiaolan Cai, Liqiang Zhang, Dapeng Lei
J. Cancer 2021; 12(24): 7380-7389. doi:10.7150/jca.62112
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PD-L1 Expression in Chinese Patients with Advanced Non-Small Cell Lung Cancer (NSCLC): A Multi-Center Retrospective Observational Study
Xin Yang, Lili Jiang, Yan Jin, Peng Li, Yingyong Hou, Jingping Yun, Chunyan Wu, Wenyong Sun, Xiangshan Fan, Dong Kuang, Weiya Wang, Jinsong Ni, Anhua Mao, Wenmin Tang, Zhenhua Liu, Jiali Wang, Suijun Xiao, Yuan Li, Dongmei Lin
J. Cancer 2021; 12(24): 7390-7398. doi:10.7150/jca.63003
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Diagnostic Performance of Diffusion MRI for differentiating Benign and Malignant Nonfatty Musculoskeletal Soft Tissue Tumors: A Systematic Review and Meta-analysis
Qian Wang, Xinguang Xiao, Yanchang Liang, Hao Wen, Xiaopeng Wen, Meilan Gu, Cuiping Ren, Kunbin Li, Liangwen Yu, Liming Lu
J. Cancer 2021; 12(24): 7399-7412. doi:10.7150/jca.62131
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GALNT6 Knockdown Inhibits the Proliferation and Migration of Colorectal Cancer Cells and Increases the Sensitivity of Cancer Cells to 5-FU
Xiangdong Peng, Xueru Chen, Xiuting Zhu, Ling Chen
J. Cancer 2021; 12(24): 7413-7421. doi:10.7150/jca.62332
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Interaction of CD147 and human epididymis protein 4 promotes invasion and metastasis of ovarian cancer
Lingling Gao, Xin Nie, Gou Rui, Yue Qi, Juanjuan Liu, Bei Lin
J. Cancer 2021; 12(24): 7422-7435. doi:10.7150/jca.62440
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Association between Platelet Count with 1-year Survival in Patients with Cancer Cachexia
Yuying Liu, Yizhong Ge, Qinqin Li, Guotian Ruan, Qi Zhang, Xi Zhang, Meng Tang, Mengmeng Song, Xiaowei Zhang, Xiangrui Li, Kangping Zhang, Ming Yang, Chunlei Hu, Tong Liu, Hailun Xie, Yongbing Chen, Kaiying Yu, Minghua Cong, Wei Li, Zhengping Wang, Hanping Shi
J. Cancer 2021; 12(24): 7436-7444. doi:10.7150/jca.62788
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PTPRO is a therapeutic target and correlated with immune infiltrates in pancreatic cancer
Xuben Hou, Jintong Du, Hao Fang
J. Cancer 2021; 12(24): 7445-7453. doi:10.7150/jca.64661
[Abstract] [Full text] [PDF]


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Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway
Jing Zhang, Pengfei Li, Ting Li, Zhiqin Zhou, Huiling Wu, Lei Zhang
J. Cancer 2021; 12(24): 7465-7476. doi:10.7150/jca.62873
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High-performance Collective Biomarker from Liquid Biopsy for Diagnosis of Pancreatic Cancer Based on Mass Spectrometry and Machine Learning
Tomohiko Iwano, Kentaro Yoshimura, Genki Watanabe, Ryo Saito, Sho Kiritani, Hiromichi Kawaida, Takeshi Moriguchi, Tasuku Murata, Koretsugu Ogata, Daisuke Ichikawa, Junichi Arita, Kiyoshi Hasegawa, Sen Takeda
J. Cancer 2021; 12(24): 7477-7487. doi:10.7150/jca.63244
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Epithelial-to-Mesenchymal Transition in Pancreatic Cancer is associated with Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging
Philipp Mayer, Anne Kraft, Wilfried Roth, Thilo Hackert, Frank Bergmann, Hans-Ulrich Kauczor, Verena Steinle, Ekaterina Khristenko, Miriam Klauss, Matthias M. Gaida
J. Cancer 2021; 12(24): 7488-7497. doi:10.7150/jca.63633
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Prognostic value of LINC02560 in colorectal cancer correlates with tumor microenvironment immunity
Chunying Luo, Fahui Liu, Weichao Su, Puze Long, Jiadong Liang, Wanyun Hou, Haifeng Jiang, Xidai Long, Guoqiang Su
J. Cancer 2021; 12(24): 7507-7517. doi:10.7150/jca.64940
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B7-H3 inhibits apoptosis of gastric cancer cell by interacting with Fibronectin
Meiyun Sun, Jinjing Xie, Dongze Zhang, Chunyang Chen, Simin Lin, Yan Chen, Guangbo Zhang
J. Cancer 2021; 12(24): 7518-7526. doi:10.7150/jca.59263
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Reviews

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The Regulatory Network of MicroRNA in the Metabolism of Colorectal Cancer
Wangji Li, Yan Lu, Changda Ye, Manzhao Ouyang
J. Cancer 2021; 12(24): 7454-7464. doi:10.7150/jca.61618
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Aberrant lipid metabolism in cancer cells and tumor microenvironment: the player rather than bystander in cancer progression and metastasis
Xiujing Yu, Shuyi Mi, Jun Ye, Guochun Lou
J. Cancer 2021; 12(24): 7498-7506. doi:10.7150/jca.64833
[Abstract] [Full text] [PDF]