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Volume 15 (15); 2024

Research Papers

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ABO/Rh Blood Group and Cervical Cancer Survival: Results from Our Own and Other Studies Vincenzo Dario Mandato, Federica Torricelli, Valentina Mastrofilippo, Ilaria Vacca, Beatrice Melli, Matteo Generali, Gianluca Annunziata, Debora Pirillo, Giovanni D'Ippolito, Gino Ciarlini, Lorenzo Aguzzoli J. Cancer 2024; 15(15): 4777-4788. doi:10.7150/jca.95245 Full text PDF PubMed PMC


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Prognostic Value of Tumor Deposits in Patients with Colorectal Cancer Manuel Díez Alonso, Fernando Mendoza Moreno, Cristina Vera Mansilla, Belén Matías, Rubén Jimenez, Youssef Allaoua, Ignacio Busteros Moraza, Alberto Vilar, Silvestra Barrena, Raúl Díaz-Pedrero, Miguel A Ortega, Melchor Alvarez de Mon, Alberto Gutierrez J. Cancer 2024; 15(15): 4789-4800. doi:10.7150/jca.96655 Full text PDF PubMed PMC


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Capsaicin exerts synergistic pro-apoptotic effects with cisplatin in TSCC through the calpain pathway via TRPV1 Xin-Yue Zhou, Qi-Wei Zhao, Zhuang Li, Xia-Yang Liu, Yu Wang, Feng-Hua Wu, Min Zhao, Yan-Mei Zhang, Gang Zhao, Guo-Hua Yang, Xiao-Hong Guo J. Cancer 2024; 15(15): 4801-4817. doi:10.7150/jca.98075 Full text PDF PubMed PMC


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Prognostic Value and Immune Landscapes of Four Types of RNA Modification Writer-Related LncRNAs Signature in Lung Adenocarcinoma Yongmei Qian, Qicheng Zhang, Yinghui Ren, Limin Cao, Sijia Zheng, Bingbing Li, Xiang Wu, Zhaowei Meng, Ke Xu J. Cancer 2024; 15(15): 4818-4837. doi:10.7150/jca.96755 Full text PDF PubMed PMC


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Determination of the Immunomodulatory Role of OTOP2 in Colon Adenocarcinoma Chenglu Lu, Shuai Chen, Shasha Liu, huimin Liu, Lin Sun, Yan Sun J. Cancer 2024; 15(15): 4838-4852. doi:10.7150/jca.95622 Full text PDF PubMed PMC


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METTL3 Inhibition Suppresses Cell Growth and Survival in Colorectal Cancer via ASNS Downregulation Yang Yu, Yanan Hai, Hongfeng Zhou, Wenfang Bao, Xiaowei Hu, Yong Gao, Jin Wu J. Cancer 2024; 15(15): 4853-4865. doi:10.7150/jca.96760 Full text PDF PubMed PMC


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Network pharmacology and biological verification of morusin's therapeutic mechanisms in inhibiting nasopharyngeal carcinoma growth Zhang Peng, Ran Hong, Yang Dunhui, Wang Zhen, Wu Yongjin, Zeng Xianhai J. Cancer 2024; 15(15): 4866-4878. doi:10.7150/jca.97044 Full text PDF PubMed PMC


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Integrated bioinformatics analysis and experimental validation to understand tryptophan metabolism-related genes in hepatocellular carcinoma Hao Chen, Wu Sun, Mengxiao Xie, Zhenhan Li, Bofeng Chen, Tao Zhang, Le Lv, Lizhen Wang, Linming Lu, Qianli Tang, Liangping Luo J. Cancer 2024; 15(15): 4879-4892. doi:10.7150/jca.91306 Full text PDF PubMed PMC


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Comparison of Short-term and Long-term Outcomes after Different Reconstructions between Totally Laparoscopic Distal Gastrectomy and Laparoscopic-assisted Distal Gastrectomy for Gastric Cancer: a Retrospective Analysis at a High-volume Center Qingya Li, Mengpei Yan, Fengyuan Li, Zheng Li, Linjun Wang, Diancai Zhang, Hao Xu, Zekuan Xu, Sen Wang J. Cancer 2024; 15(15): 4893-4901. doi:10.7150/jca.97786 Full text PDF PubMed PMC


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Preliminary study on the active substances and cellular pathways of lactic acid bacteria for colorectal cancer treatment Si-Hui Zhao, Shu-Ming Zhang, Jin-Wei Yang, Chen-Jian Liu, Xue-Qin Zeng, Yuan-Lian Zhang, Si-Qian Chen, Zhi-Min Zhao, Yun-Xin Xia, Xiao-Ran Li, Yun Shang J. Cancer 2024; 15(15): 4902-4921. doi:10.7150/jca.94530 Full text PDF PubMed PMC


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DNA methylation profiling deciphers three EMT subtypes with distinct prognoses and therapeutic vulnerabilities in breast cancer Shihao Sun, Shuang Chen, Nan Wang, Zehao Hong, Yi Sun, Yijia Xu, Jiangrui Chi, Xinxing Wang, Lin Li J. Cancer 2024; 15(15): 4922-4938. doi:10.7150/jca.96096 Full text PDF PubMed PMC


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N6-methyladenosine-modified circ_0006168 promotes epithelial mesenchymal transition via miR-384/STAT3/Snail axis in esophageal squamous cell carcinoma Guandi Wu, Qin Hou, Zhe Liu, Zejin Pu, Lingfei Wu J. Cancer 2024; 15(15): 4939-4954. doi:10.7150/jca.97533 Full text PDF PubMed PMC


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Unlocking the Therapeutic Potential: Harnessing miR-125a-5p To Enhance Autophagy and Apoptosis in Pancreatic Cancer through Targeting STAT3 Lujuan Pan, Zongshuai Qin, Qinghong Zhou, Pin Zheng, Hua Li, Xihan Zhou, Yueqiu Qin J. Cancer 2024; 15(15): 4955-4968. doi:10.7150/jca.97102 Full text PDF PubMed PMC


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Bidirectional Mendelian Randomization of Causal Relationship between Inflammatory Cytokines and Different Pathological Types of Lung Cancer Xinhang Hu, Shouzhi Xie, Xuyang Yi, Yifan Ouyang, Wangcheng Zhao, Zhi Yang, Zhe Zhang, Li Wang, Xingchun Huang, Muyun Peng, Fenglei Yu J. Cancer 2024; 15(15): 4969-4984. doi:10.7150/jca.98301 Full text PDF PubMed PMC


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Prognostic and immunotherapeutic significances of M2 macrophage-related genes signature in lung cancer Haixia Wu, Yilin Yu, Wei Wang, Gen Lin, Shaolin Lin, Jiguang Zhang, Zhaojun Yu, Jiewei Luo, Deju Ye, Wu Chi, Xing Lin J. Cancer 2024; 15(15): 4985-5006. doi:10.7150/jca.98044 Full text PDF PubMed PMC


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CXCL1 promotes cell migration in hepatocellular carcinoma by regulating the miR-30b-5p/ICAM-1 axis Yi-Hsin Chen, Chih-Chun Chu, Augusta I-Chin Wei, Ju-Fang Liu, Hong-Shiee Lai J. Cancer 2024; 15(15): 5007-5019. doi:10.7150/jca.95816 Full text PDF PubMed PMC


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The impact of tumor size on the prognosis and chemotherapy efficacy in stage I/II colon cancer patients Jiahe Yang, Shichao Li, Yulu Zhao, Fangyuan Yang, Qian Wang, Lan Ding, Cheng Chen, Xiaoyuan Chu J. Cancer 2024; 15(15): 5020-5027. doi:10.7150/jca.95743 Full text PDF PubMed PMC


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Screening of PDSS1 as a Potential Biomarker for Hepatocellular Carcinoma Based on a Copper-Related Prognostic Signature through Bulk and Single-cell RNA-sequencing Analysis Kainan Lin, Jingwei Cai, Siyuan Pan, Xuefei Yu, Yiwu Qiu, Zhangguo Ying, He Feng, Lizhuo Zhang, Yanyang Liu, Huize Shen, Yangjian Hong, Qinglin Li, Renan Jin J. Cancer 2024; 15(15): 5028-5045. doi:10.7150/jca.96867 Full text PDF PubMed PMC


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Prognostic role of immunohistochemical PTEN (phosphatase and tensin homolog) expression and PTEN (rs701848) genotypes among Egyptian patients with different stages of colorectal cancer Heba Ahmed Osman, Mohammed H. Hassan, Abdelaziz Mostafa Toema, Amira A. Abdelnaby, Mahmoud A. Abozeid, Mohamed Abdelshafy Mohamed, Abdelkader Ahmed Hashim, AbdAlraheem Husein, Abdelazeem E. Ahmed, Sameh Salaheldin Elsayed, Sherief El-Ghannam, Marwa Abdelhady, Ghada M. Abdelrazek J. Cancer 2024; 15(15): 5046-5057. doi:10.7150/jca.97553 Full text PDF PubMed PMC


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Development and Validation of an Interpretable Machine Learning Prediction Model for Total Pathological Complete Response after Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer: Multicenter Retrospective Analysis Ziran Zhang, Bo Cao, Jinghua Wu, Chengtian Feng J. Cancer 2024; 15(15): 5058-5071. doi:10.7150/jca.97190 Full text PDF PubMed PMC


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COA6 promotes the oncogenesis and progression of breast cancer by oxidative phosphorylation pathway Xiaoxia Jin, Xinyan Chen, Haiyan Yu, Yushan Liu, Xiaoyun Lu, Haibing Yin, Wencheng Dai J. Cancer 2024; 15(15): 5072-5084. doi:10.7150/jca.98570 Full text PDF PubMed PMC


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The combination of single-cell and RNA sequencing analysis decodes the melanoma tumor microenvironment and identifies novel T cell-associated signature genes Sihan Luo, Daiyue Wang, Jiajie Chen, Shaocheng Hong, Yuanyuan Fang, Lu Cao, Liang Yong, Shengxiu Liu J. Cancer 2024; 15(15): 5085-5100. doi:10.7150/jca.96484 Full text PDF PubMed PMC


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ELF4 was a prognostic biomarker and related to immune infiltrates in glioma Zhongwei Zhuang, Chunyu Zhang, Yinqiu Tan, Jing Zhang, Chunlong Zhong J. Cancer 2024; 15(15): 5101-5117. doi:10.7150/jca.96886 Full text PDF PubMed PMC


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Dysregulation of transcripts SMAD4-209 and SMAD4-213 and their respective promoters in colon cancer cell lines Tamara Babic, Milena Ugrin, Sanja Jeremic, Milan Kojic, Jelena Dinic, Bojana Banovic Djeri, Jerome Zoidakis, Aleksandra Nikolic J. Cancer 2024; 15(15): 5118-5131. doi:10.7150/jca.98911 Full text PDF PubMed PMC

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