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Volume 11 (7); 2020

Research Papers

Loss of SUSD2 expression correlates with poor prognosis in patients with surgically resected lung adenocarcinoma
Wei Guo, Fei Shao, Sijin Sun, Peng Song, Lei Guo, Xuemin Xue, Guochao Zhang, Hao Zhang, Yibo Gao, Bin Qiu, Fengwei Tan, Shugeng Gao, Jie He
J. Cancer 2020; 11(7): 1648-1656. doi:10.7150/jca.39319
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Knock down of Fas-Associated Protein with Death Domain (FADD) Sensitizes Osteosarcoma to TNFα-induced Cell Death
Mario G. Hollomon, LaNisha Patterson, Janice Santiago-O'Farrill, Eugenie S. Kleinerman, Nancy Gordon
J. Cancer 2020; 11(7): 1657-1667. doi:10.7150/jca.38721
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Development and Validation of a Novel Recurrence Risk Stratification for Initial Non-Muscle Invasive Bladder Cancer in the Han Chinese Population
Zhiyong Wang, Wansheng Gao, Jian Li, Tianen Wang, Man Zhu, Yu Duan
J. Cancer 2020; 11(7): 1668-1678. doi:10.7150/jca.38649
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Curcumol inhibits the proliferation and metastasis of melanoma via the miR-152-3p/PI3K/AKT and ERK/NF-κB signaling pathways
Ning Ning, Sulai Liu, Xiehong Liu, Zeyu Tian, Yu Jiang, Nanhui Yu, Boyu Tan, Hao Feng, Xing Feng, Lianhong Zou
J. Cancer 2020; 11(7): 1679-1692. doi:10.7150/jca.38624
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Markers in Endometrial Cancer
Caifeng Wang, Davis A. Tran, Melinda Z. Fu, Wei Chen, Sidney W. Fu, Xu Li
J. Cancer 2020; 11(7): 1693-1701. doi:10.7150/jca.41943
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognosis of colorectal cancer patients is associated with the novel log odds of positive lymph nodes scheme: derivation and external validation
Qing-Wei Zhang, Chi-Hao Zhang, Yuan-Bo Pan, Alberto Biondi, Valeria Fico, Roberto Persiani, Shan Wu, Yun-Jie Gao, Hui-Min Chen, Ou-Min Shi, Zhi-Zheng Ge, Xiao-Bo Li
J. Cancer 2020; 11(7): 1702-1711. doi:10.7150/jca.38180
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Identification of Key Gene Expression Signature and Biological Pathways in Metastatic Renal Cell Carcinoma
Lin Bao, Ye Zhao, ChenChen Liu, Qi Cao, Yu Huang, Ke Chen, Zhengshuai Song
J. Cancer 2020; 11(7): 1712-1726. doi:10.7150/jca.38379
[Abstract] [Full text] [PDF] [PubMed] [PMC]

FKBP4 is a malignant indicator in luminal A subtype of breast cancer
Hanchu Xiong, Zihan Chen, Wenwen Zheng, Jing Sun, Qingshuang Fu, Rongyue Teng, Jida Chen, Shuduo Xie, Linbo Wang, Xiao-Fang Yu, Jichun Zhou
J. Cancer 2020; 11(7): 1727-1736. doi:10.7150/jca.40982
[Abstract] [Full text] [PDF] [PubMed] [PMC]

LncRNA NRON promotes the proliferation, metastasis and EMT process in bladder cancer
Tiefu Xiong, Chenchen Huang, Jianfa Li, Shaokang Yu, Fangfang Chen, Zeng Zhang, Chengle Zhuang, Yawen Li, Changshui Zhuang, Xinbo Huang, Jing Ye, Fangting Zhang, Yaoting Gui
J. Cancer 2020; 11(7): 1751-1760. doi:10.7150/jca.37958
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Construction and validation of an eight-gene signature with great prognostic value in bladder cancer
Xin Yan, Xun Fu, Zi-Xin Guo, Xiao-Ping Liu, Tong-Zu Liu, Sheng Li
J. Cancer 2020; 11(7): 1768-1779. doi:10.7150/jca.38741
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors
Vincenzo Borgna, Lorena Lobos-González, Francisca Guevara, Eduardo Landerer, Maximiliano Bendek, Rodolfo Ávila, Verónica Silva, Claudio Villota, Mariela Araya, Alexis Rivas, Constanza López, Teresa Socias, Jorge Castillo, Luis Alarcón, Luis O. Burzio, Verónica A. Burzio, Jaime Villegas
J. Cancer 2020; 11(7): 1780-1791. doi:10.7150/jca.38880
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Clinical and functional significance of CHK1-S, an alternatively spliced isoform of the CHK1 gene, in hepatocellular carcinoma
Guanghui Hu, Shuren Wang, Yu Wang, Yang Gao, Hongxia Zhu, Mei Liu, Ningzhi Xu, Liming Wang
J. Cancer 2020; 11(7): 1792-1799. doi:10.7150/jca.39443
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3
Xinye Cui, Han Zhang, An'na Cao, Liang Cao, Xiang Hu
J. Cancer 2020; 11(7): 1800-1807. doi:10.7150/jca.39562
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Comparison of the prognostic difference between ypTNM and equivalent pTNM stages in esophageal squamous cell carcinoma based on the 8th edition of AJCC classification
Dongxian Jiang, Hao Wang, Qi Song, Haixing Wang, Qun Wang, Lijie Tan, Yingyong Hou
J. Cancer 2020; 11(7): 1808-1815. doi:10.7150/jca.34567
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Comparison of the benefits of celecoxib combined with anticancer therapy in advanced non-small cell lung cancer: A meta-analysis
Wei Zhang, Lilan Yi, Jie Shen, Hongman Zhang, Peng Luo, Jian Zhang
J. Cancer 2020; 11(7): 1816-1827. doi:10.7150/jca.35003
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Aminooxyacetic acid (AOAA) sensitizes colon cancer cells to oxaliplatin via exaggerating apoptosis induced by ROS
Taohua Yue, Shuai Zuo, Dingfang Bu, Jing Zhu, Shanwen Chen, Yongchen Ma, Ju Ma, Shihao Guo, Long Wen, Xiaoqian Zhang, Jianwen Hu, Yurong Wang, Zihao Yao, Guowei Chen, Xin Wang, Yisheng Pan, Pengyuan Wang, Yucun Liu
J. Cancer 2020; 11(7): 1828-1838. doi:10.7150/jca.35375
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Study of the S-1 or Capecitabine as First-line Regimen in Patients with Metastatic Colorectal Cancer: A Real World Study
Yanan Guo, Tongsen Zheng, Chunhui Zhang, Yanqiao Zhang
J. Cancer 2020; 11(7): 1839-1845. doi:10.7150/jca.36929
[Abstract] [Full text] [PDF] [PubMed] [PMC]

DEAD-box RNA Helicase 39 Promotes Invasiveness and Chemoresistance of ER-positive Breast Cancer
Xiudi Wang, Peipei Li, Chenying Wang, Dagui Zhang, Linghui Zeng, Xiyong Liu, Jiajin Lin
J. Cancer 2020; 11(7): 1846-1858. doi:10.7150/jca.37247
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Activated STAT3 Could Reduce Survival in Patients with Esophageal Squamous Cell Carcinoma by Up-regulating VEGF and Cyclin D1 Expression
Nan Zhang, Min Zhang, Zhou Wang, Wei Gao, Zhi-Gang Sun
J. Cancer 2020; 11(7): 1859-1868. doi:10.7150/jca.38798
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Novel candidate biomarkers of origin recognition complex 1, 5 and 6 for survival surveillance in patients with hepatocellular carcinoma
Xiang-Kun Wang, Qiao-Qi Wang, Jian-Lu Huang, Lin-Bo Zhang, Xin Zhou, Jun-Qi Liu, Zi-Jun Chen, Xi-Wen Liao, Rui Huang, Cheng-Kun Yang, Guang-Zhi Zhu, Chuang-Ye Han, Xin-Ping Ye, Tao Peng
J. Cancer 2020; 11(7): 1869-1882. doi:10.7150/jca.39163
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Compound Kushen injection combined with platinum-based chemotherapy for stage III/IV non-small cell lung cancer: A meta-analysis of 37 RCTs following the PRISMA guidelines
Hongwei Chen, Xiaojun Yao, Ting Li, Christopher Wai-Kei Lam, Ruonan Zhang, Huixia Zhang, Jue Wang, Wei Zhang, Elaine Lai-Han Leung, Qibiao Wu
J. Cancer 2020; 11(7): 1883-1898. doi:10.7150/jca.40267
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Pulmonary Tuberculosis is Associated with Elevated Risk of Lung cancer in Korea: The Nationwide Cohort Study
Chang-Mo Oh, Yun-Ho Roh, Dohee Lim, Hyun-Joo Kong, Hyunsoon Cho, Bin Hwangbo, Young-Joo Won, Kyu-Won Jung, Kyungwon Oh
J. Cancer 2020; 11(7): 1899-1906. doi:10.7150/jca.37022
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Circular RNA CircHIPK3 Promotes Gemcitabine Sensitivity in Bladder Cancer
Fang Xie, Ning Zhao, Hui Zhang, Dalong Xie
J. Cancer 2020; 11(7): 1907-1912. doi:10.7150/jca.39722
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Histone deacetylase inhibitor MGCD0103 causes cell cycle arrest, apoptosis, and autophagy in liver cancer cells
Bo Liao, Quan Sun, Yufeng Yuan, Yuchun Yin, Jianguo Qiao, Ping Jiang
J. Cancer 2020; 11(7): 1915-1926. doi:10.7150/jca.34091
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Sensitization of Carboplatinum- and Taxol-Resistant High-Grade Serous Ovarian Cancer Cells Carrying p53, BRCA1/2 Mutations by Emblica officinalis (Amla) via Multiple Targets
Alok De, Archana De, Ramratan Sharma, William Suo, Mukut Sharma
J. Cancer 2020; 11(7): 1927-1939. doi:10.7150/jca.36919
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Development and validation of a 4-gene combination for the prognostication in lung adenocarcinoma patients
Xiao-Hong Yin, Li-Ping Yu, Xiao-Hong Zhao, Qin-Mei Li, Xiao-Ping Liu, Li He
J. Cancer 2020; 11(7): 1940-1948. doi:10.7150/jca.37003
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Nanocrystallized Oleanolic Acid Better Inhibits Proliferation, Migration and Invasion in Intracranial Glioma via Caspase-3 Pathway
Ruicheng Fan, Heng Wang, Liyuan Zhang, Teng Ma, Yanping Tian, Hongli Li
J. Cancer 2020; 11(7): 1949-1958. doi:10.7150/jca.38847
[Abstract] [Full text] [PDF] [PubMed] [PMC]

High Expression of Long Noncoding RNA PCNA-AS1 Promotes Non-Small-Cell Lung Cancer Cell Proliferation and Oncogenic Activity via Upregulating CCND1
Chuanyong Wu, Xiao-ting Zhu, Lei Xia, Lin Wang, Wenjun Yu, Qiaomei Guo, Mingna Zhao, Jiatao Lou
J. Cancer 2020; 11(7): 1959-1967. doi:10.7150/jca.39087
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Analysis of Clinical Target Volume Delineation in Local-regional Failure of Nasopharyngeal Carcinoma after Intensity-modulated Radiotherapy
Xiaojing Yang, Hanru Ren, Weiwei Yu, Xiulong Zhang, Yi Sun, Yuhui Shao, Lihua Zhang, Hongling Li, Xinmiao Yang, Jie Fu
J. Cancer 2020; 11(7): 1968-1975. doi:10.7150/jca.39588
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Adverse effects of being underweight on young female breast cancer patients with lymph node metastases
Bo Chen, Jianguo Lai, Liping Guo, Danian Dai, Rong Chen, Guangnan Wei, Ning Liao
J. Cancer 2020; 11(7): 1976-1984. doi:10.7150/jca.38567
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Systematic analysis of genetic variants in cancer-testis genes identified two novel lung cancer susceptibility loci in Chinese population
Zhihua Li, Jianwei Tang, Wei Wen, Weibing Wu, Jun Wang, Jing Xu, Yue Yu, Zhicheng He, Xianglong Pan, Haixing Wei, Yining Zhu, Shuo Hu, Jing Cao, Hongbing Shen, Jun Que, Wei Wang, Quan Zhu, Liang Chen
J. Cancer 2020; 11(7): 1985-1993. doi:10.7150/jca.40002
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Preoperative weight loss is associated with poorer prognosis in operable esophageal cancer patients: A single-center retrospective analysis of a large cohort of Chinese patients
Shuishen Zhang, Yonghuang Tan, Xiaoli Cai, Kongjia Luo, Zhongkai Wu, Jianjun Lu
J. Cancer 2020; 11(7): 1994-1999. doi:10.7150/jca.40344
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

Epstein Barr Virus Associated Lymphomas and Epithelia Cancers in Humans
Richmond Ayee, Maame Ekua Ofori, Edward Wright, Osbourne Quaye
J. Cancer 2020; 11(7): 1737-1750. doi:10.7150/jca.37282
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Role of de novo cholesterol synthesis enzymes in cancer
Jie Yang, Lihua Wang, Renbing Jia
J. Cancer 2020; 11(7): 1761-1767. doi:10.7150/jca.38598
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Erratum

Phosphoglycerate Mutase 1 Predicts the Poor Prognosis of Oral Squamous Cell Carcinoma and is Associated with Cell Migration - Erratum
Dadong Zhang, Heming Wu, Xiaomin Zhang, Xu Ding, Min Huang, Meiyu Geng, Hongwei Li, Zuoquan Xie
J. Cancer 2020; 11(7): 1913-1914. doi:10.7150/jca.42410
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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